Antibothropic Serum
Mostrando 1-6 de 6 artigos, teses e dissertações.
-
1. Envenenamento experimental por Bothrops jararaca em camundongos prenhes: Eficácia do soro antibotrópico / Experimental Bothrops jararaca envenomation in pregnant mice: The effectiveness of antibothropic serum
Introdução: Neste estudo foi avaliada a eficácia do soro antibotrópico (SAB) em camundongos prenhes submetidos ao veneno bruto da serpente Bothrops jararaca (Bj). Para tanto, o veneno foi administrado em camundongos no 7,5 dia de prenhez (dp), data importante, onde, de acordo com a literatura, alterações teratogênicas podem ocorrer. Métodos: Na manh�
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/03/2011
-
2. Detection and neutralization of venom by ovine antiserum in experimental envenoming by Bothrops jararaca
In this study we optimized an enzyme-linked immunosorbent assay (ELISA) to evaluate bothropic venom levels in biological samples. These samples were obtained by two distinct protocols. In the first one, Swiss mice were injected with 1 LD50 of Bothrops jararaca (B. jararaca) venom and 15 minutes later, animals were treated with ovine antibothropic serum. Bloo
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2006
-
3. Assessment of the neutralizing potency of ovine antivenom in a swiss mice model of Bothrops jararaca envenoming
Alternative sources of anti-ophidic serum are being investigated due to the secondary effects associated with types I and II hypersensitivity reactions. In the present study we raised and evaluated the protective effect of an ovine antibothropic serum in a Swiss mice envenoming model. Ovine antiserum was obtained by immunization with seven increasing doses o
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2005-09
-
4. Efeito renal do veneno da Brothrops erythromelas e bloqueio induzido pelo fator antibotrópico do Didelphis marsupialis / Renal effect of Bothrops erythromelas venom and blockage induced by antibothropic factor from Didelphis marsupialis
Some animals present natural resistance to the effects of snake venoms that can be explained by the presence of neutralizing factors in their blood serum. The resistance of South American Didelphis marsupialis, against crotalid venoms, especially of the genus Bothrops, of utmost medical importance in Brazil, has been object of investigation in the last few y
Publicado em: 2004
-
5. Structural studies of DM43: a snake venom metalloprotease inhibitor extracted from Didelphis marsupialis opossum serum. / Estudos estruturais de DM43: Um inibidor de metaloprotease de veneno de serpente extraído do soro do gambá Didelphis marsupialis.
The natural resistance of the opossum, Didelphis marsupialis, towards snake venom is due to antibothropic factors present in the blood serum, of which DM43 is one. It is responsible for the inhibition of the hemorrhagic activity of the venom. With a view to better understanding the mechanism of action of this protein against venom metalloproteases, one of th
Publicado em: 2000
-
6. Estudos bioquimico e farmacologico da peçonha de Bothrops erythromelas
B. elythromelas is a snake found exc1usivelyin the Northeast of Brazil (from Bahia to Ceará). In this Thesis, some of the biochemical and pharmacological characteristics of this venom were examined. B. erythromelas venom possesses coagulant activity as well as proteolytic (caseinolytic), phospholipase and TAME-esterase activities. Practionation of the venom
Publicado em: 1991