Anti Radicals
Mostrando 1-12 de 56 artigos, teses e dissertações.
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1. Quantification of bergenin, antioxidant activity and nitric oxide inhibition from bark, leaf and twig of Endopleura uchi
Phytochemical investigation of Endopleura uchi led to the isolation of a gallic acid derivate, known as bergenin (2) and friedelin (1), a pentacyclic triterpene. The present work also reports the bergenin quantification in different Endopleura uchi bark, twig and leaves extracts. Our findings showed the highest bergenin concentration in bark methanol extract
Quím. Nova. Publicado em: 2020-04
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2. Anti-Helicobacter pylori and Anti-inflammatory Properties of Eugenia uniflora L.
Abstract Helicobacter pylori is a bacterium that reaches half of the world population and it’s recognized as the main cause of chronic gastritis and peptic ulcer. In this study, we evaluated the anti-H. pylori, antioxidant and immunomodulatory activities of the methanolic (MeOH) extract of Eugenia uniflora leaves and chemical profile. Anti-H. pylori activi
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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3. Evaluation of cell damage and modulation of cytokines TNF-α, IL-6 and IL-10 in macrophages exposed to PpIX-mediated photodynamic therapy
Resumo Pouco se sabe se a morte celular induzida pela terapia fotodinâmica (PDT) compromete os macrófagos (MΦ), envolvidos nas respostas imunes induzidas pela PDT. Neste estudo, foram avaliados parâmetros de citotoxicidade dos MΦ mediada pela PDT e a produção de citocinas, frente à protoporfirina IX (PpIX). MΦ peritoneais de camundongos BALB/c foram
Braz. J. Biol.. Publicado em: 26/09/2019
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4. Evaluation of the antioxidant potential of Copaifera multijuga in Ehrlich tumor-bearing mice
RESUMO Copaifera multijuga, ou copaíba, é utilizada popularmente como chá para o tratamento de diversas afecções, o que se deve à presença de substâncias antioxidantes em sua composição, que protegem as células contra danos causados pelos radicais livres. O óleo-resina da árvore é usado como antiinflamatório e antitumoral. O presente estudo av
Acta Amaz.. Publicado em: 2019-03
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5. Oxidative stress in patients with endemic pemphigus foliaceus and healthy subjects with anti-desmoglein 1 antibodies
Abstract: Background: Previous studies have shown oxidative stress in pemphigus vulgaris and pemphigus foliaceus, nevertheless, it remains unknown whether a similar response is characteristic of endemic pemphigus foliaceus in Peru. Objectives: To determine the oxidative stress response in endemic pemphigus foliaceus patients and subjects with positive for
An. Bras. Dermatol.. Publicado em: 2018-03
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6. In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195
BACKGROUND Leishmaniasis, one of the most neglected diseases, is a serious public health problem in many countries, including Brazil. Currently available treatments require long-term use and have serious side effects, necessitating the development of new therapeutic interventions. Because translocator protein (TSPO) levels are reduced in Leishmania amazonen
Mem. Inst. Oswaldo Cruz. Publicado em: 05/02/2018
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7. Preventive Effects of Ellagic Acid on Nucleus Tractus Solitarius Electrical Activity and Oxidative Stress Altered by Cerebral Global Ischemia/Reperfusion in Rat
ABSTRACT Cerebral ischemia commonly occurs when the blood flow to the entire brain or some part of the brain is disrupted. Global cerebral ischemia attenuates the nucleus tractus solitaries (NTS) EEG rhythm, increases the free radicals production and brain inflammation. Ellagic acid (EA) has antioxidative and anti-inflammatory effects against neural damages.
Braz. arch. biol. technol.. Publicado em: 08/01/2018
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8. Selenocysteine modulates resistance to environmental stress and confers anti-aging effects in C. elegans
OBJECTIVE: The free radical theory of aging suggests that cellular oxidative damage caused by free radicals is a leading cause of aging. In the present study, we examined the effects of a well-known anti-oxidant amino acid derivative, selenocysteine, in response to environmental stress and aging using Caenorhabditis elegans as a model system. METHOD: The r
Clinics. Publicado em: 2017-08
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9. Anti-inflammatory activity and chemical composition of dichloromethane extract from Piper nigrum and P. longum on permanent focal cerebral ischemia injury in rats
Abstract White pepper (Piper nigrum L.) and long pepper (Piper longum L.) belong to family Piperaceae and are commonly used as household spices and traditional medicine worldwide, specifically in China and Southeast Asia. In Traditional Chinese Hui Medicine, these herbs are widely used for treatment of stroke. Our present study investigated effects of these
Rev. bras. farmacogn.. Publicado em: 2017-06
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10. HPLC-DAD PROFILE OF PHENOLIC COMPOUNDS, CYTOTOXICITY, ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF THE AMAZON FRUIT Caryocar villosum
Piquiá (Caryocar villosum - Caryocaraceae) is a native fruit from the Amazon region rich in bioactive substances. Fruit pulp extracts were analyzed by HPLC, together with extracts obtained from fruit pulp industry residual parts, byproducts such as husks (shells) and seeds. Extracts were prepared with two ethanolic solvent systems. Phenolic substances ellag
Quím. Nova. Publicado em: 2017-06
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11. An overview about oxidation in clinical practice of skin aging
Abstract Free radicals are unstable chemical species, highly reactive, being formed by cellular entities of different tissues. Increased production of these species without proper effective action of endogenous and exogenous antioxidant systems, generates a condition of oxidative stress, potentially provider of skin disorders that extend from functional impa
An. Bras. Dermatol.. Publicado em: 2017-06
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12. Counteracting effects on free radicals and histological alterations induced by a fraction with casearins
RESUMOCasearia sylvestris Swartz é uma planta medicinal amplamente distribuída no Brasil. Ela possui atividade anti-inflamatória, antiulcerogênica e antitumoral e é popularmente utilizada para tratar envenenamentos ofídicos, ferimentos, diarreia, gripes e resfriados. Suas folhas são ricas em diterpenos clerodânicos tricíclicos oxigenados, particular
An. Acad. Bras. Ciênc.. Publicado em: 15/09/2015