Anti Nociception
Mostrando 1-12 de 56 artigos, teses e dissertações.
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1. RP-HPLC and LC–MS–MS determination of a bioactive artefact from Ipomoea pes-caprae extract
Abstract Solvents play important and critical role in natural product chemistry and could generate artefacts during the extraction and purification of metabolites from a biological matrix. This study aimed to correlate the chromatographic profile with biological activity of Ipomoea pes-caprae (L.) R. Br., Convolvulaceae, extracts obtained with hydroethanolic
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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2. A valepotriate-enriched fraction from Valeriana glechomifolia Meyer inhibits leukocytes migration and nociception in formalin test in rodents
Abstract Previous pre-clinical studies demonstrated that a valepotriates enriched fraction from Valeriana glechomifolia F.G. Mey., Caprifoliaceae, was effective against lipopolysaccharide from Escherichia coli (LPS)-induced sickness behavior as well as significantly decreased the cortical expression of pro inflammatory cytokines interleukin-1β and tumor nec
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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3. Antinociceptive and anti-inflammatory activities of a triterpene-rich fraction from Himatanthus drasticus
Himatanthus drasticus (Mart.) Plumel belongs to the Apocynaceae family and the latex from its trunk bark (Hd) is known as “janaguba milk”. This latex is widely used in Northeast Brazil, mainly in the Cariri region, for its gastroprotective, anti-inflammatory, and antitumor properties. The objective of this study was to investigate a triterpene-rich fract
Braz J Med Biol Res. Publicado em: 16/05/2019
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4. Essential oil of Pterodon polygalaeflorus Benth attenuates nociception in mice
Essential oils (EO) are volatile liquids responsible for the aroma of plants. Pterodon polygalaeflorus seeds have received widespread use in folk medicine for the treatment of inflammatory diseases. For this reason and because Pterodon polygalaeflorus seeds have great EO content, which is frequently pharmacologically active, the present study aimed to evalua
Braz J Med Biol Res. Publicado em: 04/10/2018
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5. Polysaccharide rich fractions from barks of Ximenia americana inhibit peripheral inflammatory nociception in mice Antinociceptive effect of Ximenia americana polysaccharide rich fractions
Abstract Ximenia americana L., Olacaceae, barks are utilized in folk medicine as analgesic and anti-inflammatory. The objective was to evaluate the toxicity and antinociceptive effect of polysaccharides rich fractions from X. americana barks. The fractions were obtained by extraction with NaOH, followed by precipitation with ethanol and fractionation by ion
Rev. bras. farmacogn.. Publicado em: 2017-06
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6. Antinociceptive and anti-inflammatory activities of ethanolic extract of Alafia barteri
This study analyzes the antinociceptive and anti-inflammatory properties of ethanolic leaf extract of Alafia barteri Oliv., Apocynaceae, based on its medicinal use in the treatment of toothaches, inflammation and fevers. The antinociceptive effect was assessed in mice using acetic acid-induced writhing, tail clip, tail immersion and formalin assays. Anti-inf
Rev. bras. farmacogn.. Publicado em: 2014-06
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7. Ethnopharmacological studies of Lippia origanoides
Lippia origanoides Kunth. Verbenaceae, is of great importance in the Brazilian traditional medicine. Because of it, this work had the purpose to contribute to the ethnopharmacological knowledge of L. origanoides through an ethnobotanical survey conducted within quilombola(maroon) communities of Oriximiná, Pará, Brazil. Among 254 plants cited in the survey,
Rev. bras. farmacogn.. Publicado em: 2014-04
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8. Evaluation of antinociceptive and anti-inflammatory activities of extract and fractions of Eugenia jambolana root bark and isolation of phytoconstituents
Eugenia jambolana Lam., Myrtaceae, is a widely distributed and traditionally well known plant in India. The root bark of the plant was extracted with ethanol and then successively fractionated into petroleum ether fraction, chloroform fraction, n-butanol fraction and methanol fraction. The extract and fractions of the plant material were evaluated for the an
Rev. bras. farmacogn.. Publicado em: 20/08/2013
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9. Antinociceptive and anti-inflammatory activities of an aqueous extract of Chiliotrichum diffusum
The flowers of the Chiliotrichum diffusum (G. Forst.) Kuntze, Asteraceae, have long been used in traditional medicine and rituals. In this study, the anti-inflammatory and antinociceptive activities of a decoction of the flowers were evaluated and a phytochemical analysis was performed by HPLC-DAD. In order to evaluate the antinociceptive activity, the aceti
Rev. bras. farmacogn.. Publicado em: 09/08/2013
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10. Atividade antinociceptiva e anti-inflamatória do sesquiterpeno nerolidol em camundongos. / Antinociceptive and anti-inflammatory activities of the sesquiterpeno nerolidol in mice.
Nerolidol, an acyclic sesquiterpene found as the major component in several essential oils, has antineoplastic, antimicrobial and antileishmanial activities, however its action in painful processes has never been studied. This study investigated the antinociceptive and anti-inflammatory activities of nerolidol in experimental pain and inflammation models in
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/12/2012
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11. Efeitos da Lectina da Alga Marinha Vermelha Solieria filiformis (KÃtzing) P.W. Gabrielson na NocicepÃÃo e InflamaÃÃo em Animais / Effects of the Lectin from the Red Marine Alga Solieria filiformis (KÃtzing) P.W. Gabrielson in Nociception and Inflammation in Animals
As algas marinhas sÃo fontes de compostos bioativos, os quais vÃm despertando interesse em aplicaÃÃes farmacolÃgicas. Dentre esses, destacam-se as lectinas, que sÃo (glico)proteÃnas que se ligam a mono ou oligossacarÃdeos especÃficos. O objetivo desse trabalho foi isolar a lectina da alga marinha vermelha Solieria filiformis (LSf), investigar as sua
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/02/2012
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12. Complexos metálicos de hidrazonas, tiossemicarbazonas e lapachol: atividade farmacológica e avaliação de relações estrutura-atividade
The present work comprises the synthesis and characterization of metal compounds with bioactive ligands and the study of their pharmacological profile. Anti-inflammatory, antimicrobial, antiparasitic and antitumor drug candidates were designed. Complex [Zn(LASSBio-466)H2O]2 was synthesized with salicylaldehyde-2-chlorobenzoyl hydrazone (H2LASSBio-466), while
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/02/2012