Anti Malarial
Mostrando 1-12 de 43 artigos, teses e dissertações.
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1. Study of erythrocytes as a novel drug carrier for the delivery of artemether
Resealed erythrocytes have been explored in various dimensions of drug delivery, owing to their high biocompatibility and inability to initiate immune response. The present research was designed to evaluate the drug delivery potential of erythrocytes by loading a hydrophobic anti-malarial drug, Artemether. Three different loading techniques were applied to a
Braz. J. Pharm. Sci.. Publicado em: 30/09/2019
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2. Hyperreactive malarious splenomegaly and aids: a case report
Malaria is endemic in the North of Brazil. However, Hyperreactive Malarious Splenomegaly (HMS) has been rarely described. Splenomegaly in HIV/Aids infection has a large differential diagnosis, but malaria is a cause of gross splenomegaly, regardless of the HIV status. In this paper, we report the case of a 50-year-old man, HIV positive, with massive splenome
Braz J Infect Dis. Publicado em: 2014-10
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3. Apoptosis of non-parasitised red blood cells in Plasmodium yoelii malaria
Recently, while studying erythrocytic apoptosis during Plasmodium yoelii infection, we observed an increase in the levels of non-parasitised red blood cell (nRBC) apoptosis, which could be related to malarial anaemia. Therefore, in the present study, we attempted to investigate whether nRBC apoptosis is associated with the peripheral RBC count, parasite load
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-09
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4. The antiplasmodium effects of a traditional South American remedy: Zanthoxylum chiloperone var. angustifolium against chloroquine resistant and chloroquine sensitive strains of Plasmodium falciparum
Zanthoxylum chiloperone var. angustifolium Engl., Rutaceae, is used in traditional medicine to treat fungal and protozoal infections in the central area of South America. Considering the increasing resistance of Plasmodium falciparum in malarial ridden areas, we explored the anti-plasmodial effects of three compounds isolated from Z. chiloperone. The pyranoc
Revista Brasileira de Farmacognosia. Publicado em: 17/06/2011
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5. Reduced protective effect of Plasmodium berghei immunization by concurrent Schistosoma mansoni infection
Studies on concomitant schistosomiasis and human and experimental malaria have shown a variation in the immunospecific response, as well as an increase in the severity of both parasitoses. In the present study, a murine co-infection model was used to determine the effects of a co-infection with Schistosoma mansoni and Plasmodium berghei on the protective imm
Memórias do Instituto Oswaldo Cruz. Publicado em: 2008-11
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6. Avaliation of the vitro and in vivo antimalarial activity of violacein extrated from Chromobacteriuim violaceum / Avaliação in vivo e in vitro da atividade anti-plasmodial da violaceina extraida da Chromobacterium violaceum
Violacein is a violet pigment extracted from the bacteria Gram-negative Chromobacterium violaceum. Growing bodies of evidences have implicated violacein as an antimicrobial, antifungal, antitumoral, and a moderate trypanocidal and leishmanial activity has also been observed. Herein, we evaluated the anti-malarial activity of violacein against murine and huma
Publicado em: 2008
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7. Estudo biofarmacognóstico de Acanthospermum australe (Loefl.) O. Kuntze Asteraceae / Pharmacognostic evaluation of Acanthospermum australe (Loefl.) O. Kuntze Asteraceae
Acanthospermum australe (Loefl.) O. Kuntze, conhecido popularmente no Brasil como carrapichinho pertence à família Asteraceae e é utilizado na medicina popular como hepatoprotetora, diaforética, antiblenorrágica, antimalárica, entre outras funções. O objetivo do presente trabalho foi estudar a espécie sob o aspecto botânico, químico e farmacológi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/02/2006
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8. Acute respiratory distress syndrome due to vivax malaria: case report and literature review
Severe pulmonary involvement in malaria has been frequently reported in cases of Plasmodium falciparum infection, but rarely in vivax malaria. Among the 11 previous cases of vivax-related severe respiratory involvement described in the literature, all except one developed it after the beginning of anti-malarial treatment; these appear to correspond to an exa
Brazilian Journal of Infectious Diseases. Publicado em: 2005-10
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9. Effects of autacoid inhibitors and of an antagonist on malaria infection in mice
The effects of p-chlorophenylalanine, an inhibitor of serotonin synthesis, indomethacin, an inhibitor of prostaglandin synthesis, cyproheptadine, a serotonin, bradykinin and histamine antagonist, were assessed separately and in combination with chloroquine (CQ) in Vom strains of Swiss albino mice (18-22 g) of either sex infected intraperitoneally with 1 x 10
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-08
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10. Seleção, melhoramento e nutrição da Artemisia annua L., para cultivo em região intertropical
Malaria is still one of the greatest causes of mortality in the world; in Brazil there are over 500.000 reported cases per year. Malaria, caused by the protozoa Plasmodfum, has been aggravated by the increasing resistance of Plasmodfum to the traditional drugs cloroquine and mefloquine. The study of new drugs resulted in the identification of antimalarial ac
Publicado em: 1996
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11. Synthesis of small nuclear ribonucleoprotein particles by the malarial parasite Plasmodium falciparum.
Sera from patients with autoimmune diseases have been used to identify small nuclear ribonucleoprotein particles (snRNPs) present in higher eukaryotic cells and also in dinoflagellates. Previously these sera have not detected crossreactive snRNP protein antigens of other lower eukaryotes such as yeast, Tetrahymena, or Dictyostelium. We report that anti-Sm, a
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12. Epidemiological models for the spread of anti-malarial resistance
BioMed Central.