Anthelmintics
Mostrando 13-17 de 17 artigos, teses e dissertações.
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13. Validação de metodologia analítica para o doseamento simultâneo de mebendazol e tiabendazol por cromatografia líquida de alta eficiência
The aim of this work was to develop and validate an analytical methodology for simultaneous determination of mebendazole and thiabendazole, two benzimidazoles used as anthelmintics. The method was based on high performance liquid chromatography, using a C18 column, a mobile phase composed of KH2PO4 0.05 mol L-1 and methanol 40:60 (v/v) and UV detection at 31
Química Nova. Publicado em: 2007-10
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14. Resistance of gastrointestinal nematodes to anthelmintics in sheep (Ovis aries)
O teste de redução da contagem de ovos de helmintos por grama de fezes (FECRT) foi usado para testar a eficiência dos antihelmínticos em 42 propriedades produtoras de ovinos, em cinco diferentes regiões no Estado do Paraná, Brasil. O estudo foi realizado entre Julho 1996 a Julho de 2000. Foram avaliados animais com infecção natural. Cinco drogas fora
Brazilian Archives of Biology and Technology. Publicado em: 2004-03
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15. Survey of Chemical Compounds Tested In Vitro against Rumen Protozoa for Possible Control of Bloat
Over 170 chemical agents were screened for antiprotozoal action in bovine ruminal fluid. Compounds were tested at 0.1 and 0.05% concentrations. Tested compounds included inorganic compounds, antibiotics, biocides, neuromuscular agents, arsenicals, plant and animal hormones, antimalarials, surface-active agents, anthelmintics, and many others. The most active
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16. Genetic Variability of the β-Tubulin Genes in Benzimidazole-Susceptible and -Resistant Strains of Haemonchus Contortus
Benzimidazole anthelmintics are the most common chemotherapeutic agents used to remove intestinal helminths from farm animals. The development of drug resistance within helminth populations is wide-spread and can render these drugs essentially useless. The mechanism of benzimidazole resistance appears to be common to many species ranging from fungi to nemato
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17. Screening for Microtubule-Disrupting Antifungal Agents by Using a Mitotic-Arrest Mutant of Aspergillus nidulans and Novel Action of Phenylalanine Derivatives Accompanying Tubulin Loss
The microtubule, which is one of the major targets of anthelmintics, anticancer drugs, and fungicides, is composed mainly of α- and β-tubulins. We focused on a unique characteristic of an Aspergillus nidulans benA33 mutant to screen for microtubule-disrupting antifungal agents. This mutant, which has a β-tubulin with a mutation of a single amino acid, und
American Society for Microbiology.