Amyloid
Mostrando 1-12 de 1130 artigos, teses e dissertações.
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1. Evaluation of 10-minute post-injection 11C-PiB PET and its correlation with 18F-FDG PET in older adults who are cognitively healthy, mildly impaired, or with probable Alzheimer’s disease
Objective: Positron emission tomography (PET) allows in vivo evaluation of molecular targets in neurodegenerative diseases, such as Alzheimer’s disease. Mild cognitive impairment is an intermediate stage between normal cognition and Alzheimer-type dementia. In vivo fibrillar amyloid-beta can be detected in PET using [11C]-labeled Pittsburgh compound B (11C
Brazilian Journal of Psychiatry. Publicado em: 2022
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2. Retinal amyloid angiopathy
Arquivos de Neuro-Psiquiatria. Publicado em: 2022
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3. Anti-amyloid agents for treating incipient Alzheimer’s disease: a new hope?
Brazilian Journal of Psychiatry. Publicado em: 2022
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4. Are we ready to use anti-amyloid therapy in Alzheimer's disease?
RESUMO A doença de Alzheimer (DA) é a doença neurodegenerativa mais comum. Os biomarcadores demonstraram que a patologia da DA existe ao longo do continuum da doença, desde um estágio anterior à sintomatologia, ao longo de 15 a 25 anos, até os estados sintomáticos progressivamente mais prejudicados, comprometimento cognitivo leve (CCL) e demência. E
Arquivos de Neuro-Psiquiatria. Publicado em: 2022
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5. Pure neural leprosy or amyloid neuropathy? Systematic review and clinical case report
SUMMARY OBJECTIVE: To review the literature and to report a clinical case with initial suspicion of pure neural leprosy and final diagnosis of amyloid neuropathy. METHODS: The study was conducted in two stages. In stage one, a systematic literature review was carried out, with searches performed in the PubMed, Medline, and Lilacs databases, as well as in t
Rev. Assoc. Med. Bras.. Publicado em: 2021-01
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6. Clinical Profile of Patients with Head and Neck Amyloidosis: A Single-Institution Retrospective Chart Review
Abstract Introduction Isolated amyloidosis involving the head and neck is a rare entity. The pathophysiology of the localized disease appears to be distinct from that of the systemic counterpart. Systemic progression of the localized disease is unusual, and the prognosis of the localized form is excellent. Objective To describe the demographic and clinicop
Int. Arch. Otorhinolaryngol.. Publicado em: 2020-12
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7. Hybrid Hydrogels Based on Polyethylene Glycol Bioconjugated with Silylated-Amyloidogenic Peptides
Hybrid-peptide hydrogel arrangements are a promising alternative to obtaining biocompatible structures at the nanoscopic scale. In this work, a new class of hybrid hydrogels was obtained through the sol-gel process based on the reaction between an amyloid-like octapeptide sequence [RF]4 (where R = arginine and F = phenylalanine) covalently bonded with glycin
J. Braz. Chem. Soc.. Publicado em: 2020-11
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8. Evaluation of monocyte to HDL cholesterol ratio and other inflammatory markers in patients with psoriasis,
Abstract Background Psoriasis is a chronic systemic inflammatory disease frequently associated with serious comorbidities. Objectives To investigate the systemic inflammatory burden in psoriasis and to assess the correlation between traditional and novel inflammatory markers and the severity of the disease. Methods This cross-sectional study was conducted
An. Bras. Dermatol.. Publicado em: 2020-10
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9. Early diagnosis and treatment of Alzheimer’s disease: new definitions and challenges
The prevalence of Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is expected to more than double by 2050. Studies on the pathophysiology of AD have been changing our understanding of this disorder and setting a new scenario for drug development and other therapies. Concepts like the “amyloid cascade” and the “continuum of AD,”
Braz. J. Psychiatry. Publicado em: 2020-08
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10. Transient focal neurological episodes - “amyloid spells”: a TIA mimic that should be recognized
Arq. Neuro-Psiquiatr.. Publicado em: 20/01/2020
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11. Episódios neurológicos focais transitórios - “amyloid spells”: Um AIT mimic que deve ser reconhecido
Resumen El accidente cerebrovascular isquémico (ACVi) es una importante causa de morbi-mortalidad a nivel mundial. La reperfusión con trombólisis endovenosa es utilizada desde 1996. Más recientemente, la reperfusión con trombectomía mecánica (TM) ha demostrado un beneficio consistente extendiendo la ventana terapéutica. En nuestro país existen dific
Arq. Neuro-Psiquiatr.. Publicado em: 2020-01
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12. Usefullnes of atherogenic indices and Ca-LDL level to predict subclinical atherosclerosis in patients with psoriatic arthritis?
Abstract Background: To investigate the link between carbamylated low-density lipoprotein (ca-LDL), atherogenic index of plasma (AIP), atherogenic coefficient (AC), Castelli's risk indices I and II (CRI I and II) and subclinic atherosclerosis in psoriatic arthritis (PsA). Methods: Thirty-ninepatients and 19 age, sex, body mass index matched healthy control
Adv. rheumatol.. Publicado em: 28/11/2019