Amphotericin B
Mostrando 13-24 de 1327 artigos, teses e dissertações.
-
13. Drug-induced nephrotoxicity
RESUMO A lesão renal aguda é um diagnóstico muito comum, presente em até 60% dos pacientes críticos, e sua terceira maior causa é a toxicidade de medicamentos. A nefrotoxicidade pode ser definida como qualquer lesão renal causada por medicamentos, direta ou indiretamente, tendo a insuficiência renal aguda, tubulopatias e glomerulopatias como apresent
Rev. Assoc. Med. Bras.. Publicado em: 13/01/2020
-
14. Essential Oils from Croton Species: Chemical Composition, in vitro and in silico Antileishmanial Evaluation, Antioxidant and Cytotoxicity Activities
Chemotherapy treatment of leishmaniasis is based on the use of pentavalent antimonials, but these drugs present low efficacy and high toxicity. In the search for new antileishmanial agents, essential oils (EOs) from four Croton species (C. argyrophylloides, C. jacobinensis, C. nepetifolius and C. sincorensis) were evaluated against Leishmania infantum chagas
J. Braz. Chem. Soc.. Publicado em: 24/10/2019
-
15. PEDOMETRIA APLICADA A ESTUDO COMPARATIVO ENTRE MORFINA E TRAMADOL EM BOVINOS
Resumo A analgesia com opioides é limitada ou indefinida em ruminantes. Neste trabalho, objetivou-se a realização de um estudo comparativo entre dois analgésicos opioides: a morfina e o tramadol, com base nas avaliações clínica e pedométrica de animais submetidos a artrite e sinovite experimental transitórias, desenvolvidas na articulação interfal
Ciênc. anim. bras.. Publicado em: 30/09/2019
-
16. Amphotericin-B and vancomycin-loaded chitosan nanofiber for antifungal and antibacterial application
In the present study, a mucoadhesive non-woven fiber mat (d= 116 nm) was fabricated by the electrospinning method using chitosan (80% Wt), polyethylene oxide (10% Wt), cysteine (4% Wt) and drugs (6% Wt), respectively. In addition, a comparative study was conducted to define effect of drugs and mucoadhesive agent on the nanofiber formation. FTIR, SEM, DSC and
Braz. J. Pharm. Sci.. Publicado em: 09/09/2019
-
17. Fusarium solani keratitis: role of antifungal susceptibility testing and identification to the species level for proper management
ABSTRACT We report a patient with fungal keratitis caused by a multiresistant Fusarium solani in a tertiary care hospital located in southern Brazil. A 55-year-old man with a history of ocular trauma presented with keratitis in left eye. The patient has a complicated clinical course and failed to respond to local and systemic antifungal treatment, and requir
Braz J Infect Dis. Publicado em: 09/09/2019
-
18. American tegumentary leishmaniasis: severe side effects of pentavalent antimonial in a patient with chronic renal failure
Abstract: Pentavalent antimonials are the first-line drug treatment for American tegumentary leishmaniasis. We report on a patient with chronic renal failure on hemodialysis who presented with cutaneous lesions of leishmaniasis for four months. The patient was treated with intravenous meglumine under strict nephrological surveillance, but cardiotoxicity, acu
An. Bras. Dermatol.. Publicado em: 29/07/2019
-
19. Yeasts isolated from tropical fruit ice creams: diversity, antifungal susceptibility and adherence to buccal epithelial cells
Resumo Os sorvetes à base de frutas são produtos amplamente consumidos em países tropicais e, devido à sua composição, podem ser uma boa fonte de crescimento microbiano, incluindo patógenos oportunistas. Os objetivos deste estudo foram caracterizar as populações de leveduras presentes nos sorvetes brasileiros à base de frutas e investigar sua susce
Braz. J. Food Technol.. Publicado em: 04/07/2019
-
20. Synergistic effect of terbinafine and amphotericin B in killing Fonsecaea nubica in vitro and in vivo
ABSTRACT Chromoblastomycosis is a chronic fungal infection. Itraconazole and terbinafine are the most recommended antifungal drugs for chromoblastomycosis, while amphotericin B is not usually recommended. A patient with chromoblastomycosis in our hospital showed poor clinical responses to itraconazole and terbinafine. The fungus isolated from the lesions o
Rev. Inst. Med. trop. S. Paulo. Publicado em: 19/06/2019
-
21. Candida on oral cavity of pediatric individuals with ALL and its susceptibility to nystatin and amphotericin B
RESUMO Objetivo: o objetivo deste estudo foi avaliar a prevalência e colonização de Candida na cavidade oral de indivíduos pediátricos com leucemia linfocítica aguda (LLA) e sua susceptibilidade/resistência à nistatina e à anfotericina B. Métodos: estudo transversal observacional com abordagem descritiva e analítica. A saliva foi coletada de 40
RGO, Rev. Gaúch. Odontol.. Publicado em: 06/05/2019
-
22. Cost-effectiveness analysis of diagnostic-therapeutic strategies for visceral leishmaniasis in Brazil
Abstract INTRODUCTION: Visceral leishmaniasis (VL) is fatal if not diagnosed and treated. This study aimed to estimate the cost-effectiveness of diagnostic-therapeutic alternatives for VL in Brazil. METHODS: A decision model estimated the life expectancy and costs of six diagnostic-therapeutic strategies. RESULTS: IT LEISH + liposomal amphotericin B em
Rev. Soc. Bras. Med. Trop.. Publicado em: 11/04/2019
-
23. First case report of cryptococcosis due to Cryptococcus decagattii in a pediatric patient in Argentina
Abstract We report the first case of cryptococcosis due to Cryptococcus decagattii in an immunocompetent pediatric patient from an indigenous community in Argentina with a successful outcome. Two isolates (blood, cerebrospinal fluid) were genotyped by restriction fragment length polymorphism of the orotidine monophosphate pyrophosphorylase (URA5) gene as VGI
Rev. Soc. Bras. Med. Trop.. Publicado em: 28/03/2019
-
24. Nitro-Heterocyclic compounds induce apoptosis-like effects in Leishmania (L). amazonensis promastigotes
Abstract Background: Three drugs - pentavalent antimonials, amphotericin B and pentamidine - are currently used for leishmaniasis treatment. They are administered for long periods, only parenterally, and have high cardiac, renal and hepatic toxicities. Therefore, the investigation of new compounds is required. Nitro-heterocyclic derivatives have been used a
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 11/03/2019