Amino Acid Sequence
Mostrando 1-12 de 13732 artigos, teses e dissertações.
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1. A novel mutation in PRKAR1A gene in a patient with Carney complex presenting with pituitary macroadenoma, acromegaly, Cushing's syndrome and recurrent atrial myxoma
SUMMARY Carney complex (CNC) is a rare syndrome of multiple endocrine and non-endocrine tumors. In this paper we present a 23-year-old Iranian woman with CNC who harbored a novel mutation (c.642dupT) in PRKAR1A gene. This patient presented with pituitary macroadenoma, acromegaly, recurrent atrial myxoma, Cushing's syndrome secondary to primary pigmented nodu
Arch. Endocrinol. Metab.. Publicado em: 2021-06
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2. Isolation and molecular characterization of Campylobacter jejuni from chicken and human stool samples in Egypt
Abstract Two hundred broiler chicken samples, 160 laying chicken samples and 75 human stool samples were collected in Egypt. The samples were microbiologically examined, and the C. jejuni isolates were confirmed biochemically and by PCR targeting the mapA gene of C. jejuni. The prevalence of the cadF virulence gene was then determined using PCR. A total of 1
Food Sci. Technol. Publicado em: 2021-03
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3. Galium spurium and G. aparine Resistance to ALS-Inhibiting Herbicides in Northern Greece
RESUMO: O conhecimento do nível de resistência das populações de plantas daninhas e dos herbicidas aos quais eles sobrevivem é importante para recomendar conselhos adequados aos agricultores e permitir a seleção de estratégias de gestão apropriadas. Experimentos de resposta de plantas inteiras foram realizados para estudar os níveis de resistência
Planta daninha. Publicado em: 17/10/2019
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4. In silico prediction of the functional and structural consequences of the non-synonymous single nucleotide polymorphism A122V in bovine CXC chemokine receptor type 1
Resumo O presente estudo objetivou avaliar se o polimorfismo causal A122V promove alterações nas propriedades funcionais e estruturais da proteína receptora de quimiocina CXC do tipo 1 (CXCR1) de bovino Bos taurus por análises in silico. Duas sequências de aminoácidos da CXCR1 bovina foram selecionadas a partir do banco de dados UniProtKB/Swiss-Prot:
Braz. J. Biol.. Publicado em: 18/04/2019
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5. Purification and enzymatic characterization of a novel metalloprotease from Lachesis muta rhombeata snake venom
Abstract Background: Lachesis muta rhombeata (Lmr) is the largest venomous snake in Latin America and its venom contains mainly enzymatic components, such as serine and metalloproteases, L-amino acid oxidase and phospholipases A2. Metalloproteases comprise a large group of zinc-dependent proteases that cleave basement membrane components such as fibronectin
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 17/12/2018
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6. Cell migration inhibition activity of a non-RGD disintegrin from Crotalus durissus collilineatus venom
Abstract Background: In recent decades, snake venom disintegrins have received special attention due to their potential use in anticancer therapy. Disintegrins are small and cysteine-rich proteins present in snake venoms and can interact with specific integrins to inhibit their activities in cell-cell and cell-ECM interactions. These molecules, known to inh
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 29/11/2018
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7. Detection and genetic characterization of Mamastrovirus 5 from Brazilian dogs
Abstract Mamastrovirus 5 (MAstV5), belonging to the Astroviridae (AstV) family, previously known as canine astrovirus or astrovirus-like particles, has been reported in several countries to be associated with viral enteric disease in dogs since the 1980s. Astroviruses have been detected in fecal samples from a wide variety of mammals and birds that are assoc
Braz. J. Microbiol.. Publicado em: 2018-09
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8. Improved antifungal activity of barley derived chitinase I gene that overexpress a 32 kDa recombinant chitinase in Escherichia coli host
Abstract Agricultural crops suffer many diseases, including fungal and bacterial infections, causing significant yield losses. The identification and characterisation of pathogenesis-related protein genes, such as chitinases, can lead to reduction in pathogen growth, thereby increasing tolerance against fungal pathogens. In the present study, the chitinase I
Braz. J. Microbiol.. Publicado em: 2018-06
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9. Genetic engineering of Theileria parva lactate dehydrogenase gene: a new anti-theilerial target
ABSTRACT: Theileria parva is the causative agent of East Coast Fever (ECF), a tick borne disease, which results in major economic losses in cattle. Major problems in dealing with this illness are the high cost of drugs, development of resistance, and absence of effective vaccines. Thus, exploiting new targets for cost effective and higher therapeutic value d
Pesq. Vet. Bras.. Publicado em: 2018-05
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10. HSF1 and HSPA6 as functional candidate genes associated with heat tolerance in Angus cattle
ABSTRACT The purpose of this study was to access and characterize single nucleotide polymorphisms (SNP) located within the HSF1 and HSPA6 candidate genes for adaptability in Angus breed raised in subtropical climate. Samples of DNA from 20 animals representing extreme phenotypes for adaptability traits were obtained. Sequence variations in the candidate gene
R. Bras. Zootec.. Publicado em: 05/03/2018
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11. Biofilm production by clinical isolates of Pseudomonas aeruginosa and structural changes in LasR protein of isolates non biofilm-producing
ABSTRACT Introduction: Biofilm production is an important mechanism for the survival of Pseudomonas aeruginosa and its relationship with antimicrobial resistance represents a challenge for patient therapeutics. P. aeruginosa is an opportunistic pathogen frequently associated to nosocomial infections, especially in imunocompromised hosts. Objectives: Analyz
Braz J Infect Dis. Publicado em: 2018-03
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12. BaltDC: purification, characterization and infrared spectroscopy of an antiplatelet DC protein isolated from Bothrops alternatus snake venom
Abstract Background: Snake venoms are a complex mixture of proteins, organic and inorganic compounds. Some of these proteins, enzymatic or non-enzymatic ones, are able to interact with platelet receptors, causing hemostatic disorders. The possible therapeutic potential of toxins with antiplatelet properties may arouse interest in the pharmacological areas.
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 08/02/2018