Amebicidal Activity
Mostrando 1-10 de 10 artigos, teses e dissertações.
-
1. Terpenóides em espécies do gênero salvia (lamiaceae) / Terpenoids in the genus Salvia (Lamiaceae)
O gênero Salvia L. (Lamiaceae), constituido de aproximadamente 900 espécies, possui 60 representantes no Brasil. Dentre suas propriedades medicinais destacam-se as atividades antitumoral, anti-inflamatória, cicatrizante e antibacteriana. Óleos essenciais e diterpenos de núcleos abietano, clerodano, primarano estão entre os principais constituintes quí
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
-
2. Estudo químico e biológico de espécies de croton (euphorbiaceae) nativas do Rio Grande do Sul / Chemical and biological study of species of croton (Euphorbiaceae) native of Rio Grande do Sul
The family Euphorbiaceae has been highlighted by the production of compounds of industrial interest and importance for the food. Several representatives species are of interest due to production of volatile oils. Examples are species of Croton that have medicinal properties, such as anti-inflammatory, antifungal, antimicrobial and healing. Some species of th
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
-
3. Atividade de pterocaulon polystachyum DC. (asteraceae) frente a acanthamoeba castellanii
O gênero Pterocaulon agrupa cerca de 20 espécies sendo 10 delas encontradas no Rio Grande do Sul. Várias espécies de Pterocaulon, conhecidas como "Quitoco", são utilizadas na medicina popular na forma de infusão ou decocto com diferentes fins terapêuticos. O extrato metanólico bruto e as frações de Pterocaulon polystachyum apresentam largo espectro
Publicado em: 2009
-
4. Cytokine activation of murine macrophages for in vitro killing of Entamoeba histolytica trophozoites.
Macrophage-mediated effector mechanisms against the protozoan parasite Entamoeba histolytica were studied. Unstimulated macrophages were inefficient at killing E. histolytica trophozoites in vitro and were killed by the trophozoites. Conversely, immature cells of the mononuclear phagocyte lineage (promonocytes) were shown to display a strong spontaneous ameb
-
5. Human T-lymphocyte proliferation, lymphokine production, and amebicidal activity elicited by the galactose-inhibitable adherence protein of Entamoeba histolytica.
We studied human T-lymphocyte responses to the purified Entamoeba histolytica galactose-inhibitable adherence protein. Individuals having serum anti-adherence protein antibodies possess peripheral blood lymphocytes which demonstrate antigen-specific responses to the purified adherence protein (10 micrograms/ml) and whole soluble amebic antigen (100 microgram
-
6. Tumor necrosis factor alpha augments nitric oxide-dependent macrophage cytotoxicity against Entamoeba histolytica by enhanced expression of the nitric oxide synthase gene.
Nitric oxide (NO measured as nitrite, NO2-) is the major effector molecule produced by activated macrophages for in vitro cytotoxicity against Entamoeba histolytica trophozoites. In this study, we determine whether tumor necrosis factor alpha (TNF-alpha) produced by activated bone marrow-derived macrophages (BMM) is involved in the induction of the inducible
-
7. The tumor necrosis factor alpha-stimulating region of galactose-inhibitable lectin of Entamoeba histolytica activates gamma interferon-primed macrophages for amebicidal activity mediated by nitric oxide.
Entamoeba histolytica adheres via galactose-lectin (Gal-lectin) to human colonic mucins and intestinal epithelial cells as a prerequisite to amebic invasion. Native Gal-lectin is a protective antigen in the gerbil model of amebiasis. Amino acids 596 to 1082 of Gal-lectin mediate E. histolytica adherence to target cells and stimulate tumor necrosis factor alp
-
8. Effects of magainins on ameba and cyst stages of Acanthamoeba polyphaga.
Amebic keratitis produced by Acanthamoeba spp. is an increasingly important ocular infection in extended-use contact lens wearers. Problems associated with the infection are compounded by the lack of effective and well-tolerated chemotherapeutic agents. The magainins, a group of naturally occurring and synthetic membrane-active peptide compounds, have been s
-
9. Inhibition of Acanthamoeba species by Pseudomonas aeruginosa: rationale for their selective exclusion in corneal ulcers and contact lens care systems.
Cocultivation of Acanthamoeba castellanii and Acanthamoeba polyphaga with live Pseudomonas aeruginosa and with broth filtrates of P. aeruginosa proved equally lethal to the Acanthamoeba spp. The P. aeruginosa-induced amebicidal activity is apparently toxin mediated and has two operative modes: it can function through binding of P. aeruginosa to the ameba mem
-
10. In Vitro And In Vivo Activity of 5-Fluorocytosine on Acanthamoeba
The results of our studies indicated that the avirulent Neff strain of Acanthamoeba was more susceptible to the activity of the anti-metabolite 5-fluorocytosine (5-FC) than was the virulent A-1 strain or a mouse brain reisolate of this strain, designated A-3. Results of competition experiments in which cultures were exposed simultaneously to 5-FC and either