Amaryllidaceae
Mostrando 1-12 de 52 artigos, teses e dissertações.
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1. Isolation, Absolute Configuration and Cytotoxic Activities of Alkaloids from Hippeastrum goianum (Ravenna) Meerow (Amaryllidaceae)
The phytochemical study of Hippeastrum goianum led to the identification of 13 compounds by means of gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR). Compounds 7-demethoxy-9-O-methylhostasine (1) and 7-deoxi-trans-dihydronarciclasine (2) had their absolute configurations determined by vibrational circular dichroism (VCD). Th
J. Braz. Chem. Soc.. Publicado em: 2020-10
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2. Development and Validation of a UPLC-ESI-MS Method for Quantitation of the Anti-Alzheimer Drug Galantamine and other Amaryllidaceae Alkaloids in Plants
Our study aimed at the development of a method based on ultra-performance liquid chromatography coupled to mass spectrometry (UPLC-ESI-MS) using selected ion monitoring for the simultaneous quantitation of the alkaloids galantamine, pseudolycorine, sanguinine and narciclasine in Amaryllidaceae species (Hippeastrum elegans, Habranthus cf. irwinianus, Hymenoca
J. Braz. Chem. Soc.. Publicado em: 2020-02
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3. Galanthamine and other Amaryllidaceae related alkaloids are inhibitors of α7, α4β2 and α3β4 nicotinic acetylcholine receptors
Abstract Galanthamine is an Amaryllidaceae-derived acetylcholinesterase inhibitor used to treat memory impairment in Alzheimer's disease and vascular dementia. There is evidence that galanthamine, in addition to its effects on acetylcholinesterase, may enhance or inhibit brain nicotinic acetylcholine receptors, which could increase or decrease the therapeuti
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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4. [PROVISIONAL] Does the chromosomal position of 35S rDNA sites influence their transcription? A survey on Nothoscordum species (Amaryllidaceae)
Abstract 35S ribosomal DNA (rDNA) sites are the regions where the ribosomal genes 18S, 5.8S and 25S, responsible for the formation of the nucleoli, are found. The fact that rDNA sites have non-random distribution on chromosomes suggests that their position on the chromosome may influence their transcription. In order to identify if the preferentially transcr
Genet. Mol. Biol.. Publicado em: 29/08/2019
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5. In vitro Antiplasmodial Activities of Alkaloids Isolated from Roots of Worsleya procera (Lem.) Traub (Amaryllidaceae)
A combined phytochemical, crystallographic and biological study of Worsleya procera roots was performed. Fifteen alkaloids were identified by gas chromatography mass spectrometry (GC-MS) and seven of them were isolated. The structures of the alkaloids were elucidated by spectroscopic methods, and a detailed crystallographic study of tazettine was carried out
J. Braz. Chem. Soc.. Publicado em: 12/08/2019
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6. Influence of in vitro micropropagation on lycorine biosynthesis and anticholinesterase activity in Hippeastrum goianum
ABSTRACT Hippeastrum goianum (Ravenna) Meerow, Amaryllidaceae, is an endemic species from the Cerrado, Brazil; there are only few studies about its chemistry or biological activity. This study aimed to investigate the occurrence of lycorine in extracts from in vitro H. goianum plantlets, as well as evaluate a possible inhibition of acetylcholinesterase. The
Rev. bras. farmacogn.. Publicado em: 27/05/2019
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7. Aclimatização ex vitro de Hippeastrum reticulatum (Amaryllidaceae) em diferentes substratos
RESUMO: Hippeastrum spp. são espécies herbáceas pertencentes à família Amaryllidaceae, muito comercializadas mundialmente como plantas envasadas para ambientes de interior. Objetivando caracterizar química e fisicamente, e comparar cinco substratos na aclimatização, mudas micropropagadas de Hippeastrum reticulatum var. striatifolium (Herb) Herb., com
Cienc. Rural. Publicado em: 03/12/2018
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8. Rhodolirium andicola: a new renewable source of alkaloids with acetylcholinesterase inhibitory activity, a study from nature to molecular docking
ABSTRACT Acetylcholinesterase is an important target for control of neurodegenerative diseases causing cholinergic signaling deficit. Traditionally, galanthamine has been used as an Amaryllidaceae-derived acetylcholinesterase inhibitor, although new Amaryllidaceae plants could serve as source for better acetylcholinesterase inhibitors. Therefore, the objecti
Rev. bras. farmacogn.. Publicado em: 2018-01
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9. REGISTRO DE Xanthopastis timais EM AMARÍLIS E EFEITO DO EXTRATO DE GRAVIOLA NA MORTALIDADE LARVAL
RESUMO O objetivo deste trabalho foi relatar a ocorrência em Alagoas da espécie Xanthopastis timais (Cramer, 1780) (Lepidoptera: Noctuidae) em amarílis (Hippeastrum hybridum Hort., Amaryllidaceae) e avaliar o uso do extrato de sementes de graviola, Annona muricata L. (Annonaceae), estimando as concentrações letais (CL50 e CL99) para as lagartas, bem com
Rev. Caatinga. Publicado em: 2017-06
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10. Identification of Alkaloids from Hippeastrum aulicum (Ker Gawl.) Herb. (Amaryllidaceae) Using CGC-MS and Ambient Ionization Mass Spectrometry (PS-MS and LS-MS)
Amaryllidaceae alkaloids are well-known isoquinolines which have demonstrated a wide range of biological activities such as antiviral, anticancer, acetylcholinesterase inhibition, antimalarial, among others. Mass spectrometry (MS) studies based on capillary gas chromatography (CGC), paper spray (PS), and leaf spray (LS) ionization were carried out for alkalo
J. Braz. Chem. Soc.. Publicado em: 2017-05
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11. New lycosinine derivative from Hippeastrum breviflorum
AbstractA new lycosinine derivative, 9-O-demethyllycosinine B, was isolated from the native Brazilian Hippeastrum breviflorumHerb., Amaryllidaceae, along with the well-known alkaloids lycosinine B and lycorine. The structure of the new compound was established by physical and spectroscopic methods. 9-O-demethyllycosinine B is the third lycosinine variant ide
Rev. bras. farmacogn.. Publicado em: 2015-08
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12. Habranthus (Amaryllidaceae) do Brasil
Habranthus é um gênero com forte apelo ornamental e apresenta de 30 a 40 espécies distribuídas desde o sudeste dos Estados Unidos, México até a América do Sul. Sua delimitação, bem como das espécies, é confusa e a taxonomia é complicada, com vários casos de tipificação necessitando serem esclarecidos. Os objetivos deste estudo foram realizar o
Rodriguésia. Publicado em: 2015-03