Alloimmunization
Mostrando 1-12 de 25 artigos, teses e dissertações.
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1. Maternal-fetal alloimmunization: perinatal outcomes in a reference hospital in Northeastern Brazil
SUMMARY OBJECTIVE: To assess the prevalence of maternal alloantibodies in pregnant women at a maternity hospital in northeastern Brazil and describe their perinatal outcomes. METHODS: A retrospective cohort study reviewed maternal and newborn medical records between January 2017 and October 2018 to assess for the presence of maternal alloantibodies. RESUL
Revista da Associação Médica Brasileira. Publicado em: 2022
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2. Non-RhD (anti-E) red cell alloimmunization following platelet transfusion: a case report and implications on quality of the platelet concentrates and antibody screening protocols
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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3. Platelet antibodies identification: comparison between two laboratory tests
ABSTRACT Introduction: Platelet antibody identification is indispensable for diagnosing the human platelet antigen (HPA) or human leukocyte antigen (HLA) immunization, mostly because it can restrict the compatibility and results of transfusions. Correct detection of these antibodies is of utmost importance for the diagnosis and treatment. Method: We presen
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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4. Serologic strategy in detecting RHD altered alleles in Brazilian blood donors
ABSTRACT Background: We evaluated different technological approaches and anti-D clones to propose the most appropriate serologic strategy in detecting the largest numbers of D variants in blood donors. Methods: We selected 101 samples from Brazilian blood donors with different expressions of D in our donor routine. The tests were performed in immediate spi
Hematol., Transfus. Cell Ther.. Publicado em: 2020-10
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5. Chronic transfusion therapy effectiveness as primary stroke prophylaxis in sickle cell disease patients
Abstract Introduction About 10% of sickle cell anemia patients will have ischemic stroke. Adams showed stroke incidence reduction in children receiving monthly erythrocyte transfusions by reducing transcranial Doppler (TCD) velocities. Since then, chronic transfusion is recommended as primary stroke prophylaxis. This study aims to assess the effectiveness o
Hematol., Transfus. Cell Ther.. Publicado em: 2020-03
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6. Methods for blood group antigens detection: cost-effectiveness analysis of phenotyping and genotyping
Abstract Background Alloimmunization is a major problem in transfusion practice due to the clinical complications of the patients and the difficulty of choosing a unit of compatible blood product. Serological methods are widely used in blood banks, but they not always determine the phenotype. Thus, genotyping is an important complement to the serology tool
Hematol., Transfus. Cell Ther.. Publicado em: 15/04/2019
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7. Clinical and epidemiological profile of alloimmunized and autoimmunized multi-transfused patients against red blood cell antigens in a blood center of Minas Gerais
ABSTRACT Background: The large diversity of red blood cell antigens favors, especially in multi-transfused patients, the occurrence of autoimmunization and alloimmunization with the risk of hemolytic transfusion reactions. Thus, this study aimed to determine the rates of alloimmunization and autoimmunization in these individuals, as well as the types of all
Hematol., Transfus. Cell Ther.. Publicado em: 2018-06
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8. Erratum to “Alloimmunization screening after transfusion of red blood cells in a prospective study” [Rev Bras Hematol Hemoter. 2012;34(3):206-211]
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-06
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9. Red blood cell storage and alloimmunization: a fact or a myth?
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-12
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10. Transfusion of older red blood cell units, cytokine burst and alloimmunization: a case-control study
BACKGROUND: Experimental data have shown that the transfusion of older red blood cell units causes alloimmunization, but the clinical applicability of this statement has never been properly assessed in non-sickle cell patients. It has been hypothesized that older units have higher numbers of cytokines, increasing the risk of alloimmunization related to antig
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-10
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11. Impact of a confirmatory RhD test on the correct serologic typing of blood donors
BACKGROUND: The RHD gene is highly polymorphic, which results in a large number of RhD variant phenotypes. Discrepancies in RhD typing are still a problem in blood banks and increase the risk of alloimmunization. In this study, the RhD typing strategy at a blood bank in Brazil was evaluated.METHODS: One-hundred and fifty-two samples typed as RhD negative and
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-10
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12. Red blood cell and leukocyte alloimmunization in patients awaiting kidney transplantation
Objective: To determine the rates of red blood cell and leukocyte alloimmunization in patients with chronic kidney disease awaiting kidney transplantation. Methods: In this cross-sectional and prospective study, the serum of 393 chronic kidney
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013-06