Alkaloids
Mostrando 13-24 de 558 artigos, teses e dissertações.
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13. 3-Aminofurostane Alkaloids from Solanum paniculatum (“Jurubeba Verdadeira”) Roots
The roots of Solanum paniculatum (Solanaceae) have extensively been used in folk medicine to treat liver infections and as a diuretic. Ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS/MS) were used for the profiling and structural characterization of alkaloids from the roots of S. paniculatum. Six
J. Braz. Chem. Soc.. Publicado em: 2020-05
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14. An analytical study of iboga alkaloids contained in Tabernanthe iboga-derived products offered by ibogaine treatment providers
Abstract Background Therapeutic properties of ibogaine in the treatment of addiction are attracting both clinicians and patients to its use. Since ibogaine is not an authorized medicine, the quality of these products is not always known, increasing the probability of adverse reactions. Objective This study collects different types of iboga-derived sample
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2020-04
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15. Minutifloroside, a New Bis-Iridoid Glucoside with Antifungal and Antioxidant Activities and Other Constituents from Palicourea minutiflora
A new bis-iridoid glucoside minutifloroside (1) was isolated from Palicourea minutiflora, together with asperuloside, (-)-epicatechin, catechin, quercetin, rutin, ursolic acid, oleanolic acid, daucosterol and two monoterpenic indole alkaloids strictosidinic acid and vincosamine. Structural characterization of the compounds was established on their spectral d
J. Braz. Chem. Soc.. Publicado em: 2020-03
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16. Development and Validation of a UPLC-ESI-MS Method for Quantitation of the Anti-Alzheimer Drug Galantamine and other Amaryllidaceae Alkaloids in Plants
Our study aimed at the development of a method based on ultra-performance liquid chromatography coupled to mass spectrometry (UPLC-ESI-MS) using selected ion monitoring for the simultaneous quantitation of the alkaloids galantamine, pseudolycorine, sanguinine and narciclasine in Amaryllidaceae species (Hippeastrum elegans, Habranthus cf. irwinianus, Hymenoca
J. Braz. Chem. Soc.. Publicado em: 2020-02
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17. CALISTEGINAS, ALCALÓIDES POLIHIDROXILADOS PRESENTES EM HORTALIÇAS: FRUTOS E TUBEROSAS
Calystegines are nortropane alkaloids with three to five hydroxyl groups. These alkaloids are recognized as glycosidase inhibitors and thus may have therapeutic potential to be exploited. There are also reports of its possible toxic effects when they are present in foods. Commercial cultivars of human consumption in Brazil have been analyzed for calystegines
Quím. Nova. Publicado em: 2020-01
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18. Integrative Approach Based on Leaf Spray Mass Spectrometry, HPLC-DAD-MS/MS, and NMR for Comprehensive Characterization of Isoquinoline-Derived Alkaloids in Leaves of Onychopetalum amazonicum R. E. Fr.
Onychopetalum is an Amazonian botanical genus close-related with Bocageopsis and Unonopsis, whose species are used in traditional medicine. Although these genera are widely investigated from the phytochemical viewpoint, the knowledge about Onychopetalum remains almost unexplored. In order to perform a comprehensive characterization of isoquinoline-derived al
J. Braz. Chem. Soc.. Publicado em: 2020-01
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19. Synthesis, Characterization and Conformational Analysis of Two Novel 4(1H)‑Quinolinones
Quinolinones are a class of organic compounds known as alkaloids found in several plants and also can be synthesized. Their large use in therapies regards their wide biological potential like antitumor, psychiatric and neurological agents. Two substances were structurally characterized: (E)-3-(2-nitrobenzylidene)-2-(4-methoxyphenyl)-1-(phenylsulfonyl)-2,3-di
J. Braz. Chem. Soc.. Publicado em: 2020-01
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20. Phytochemical study of Waltheria viscosissima and evaluation of its larvicidal activity against Aedes aegypti
Abstract The species Waltheria viscosissima A.St.–Hil, Malvaceae, which is known as ‘malva-branca', is traditionally used in the Brazilian northeast for the treatment of coughs. This research looks towards reporting the isolation of phytoconstituents of W. viscosissima, as well as the quantification of its phenolics, total flavonoid content, and free rad
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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21. Lantana camara: Phytochemical Analysis and Antifungal Prospective
RESUMO: Neste estudo, foi feita uma análise fitoquímica e do potencial antifúngico in vitro de frutos, folhas e caule de Lantana camara L. A análise fitoquímica indicou a presença de alcaloides, flavonoides, taninos, saponinas, glicosídeos e terpenoides em frutos, caule e folhas de L. camara. A atividade antifúngica in vitro de frutos, caule e folhas
Planta daninha. Publicado em: 02/12/2019
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22. Experimental poisoning by Crotalaria lanceolata and Crotalaria pallida seeds in broilers
RESUMO: Crotalaria lanceolata E. Mey. e Crotalaria pallida Aiton. são leguminosas da família Fabaceae presentes na maioria do território brasileiro. Inicialmente foram utilizadas como adubação verde e devido sua fácil disseminação são consideradas invasoras de culturas. Através da colheita mecanizada da soja e milho pode ocorrer a contaminação de
Pesq. Vet. Bras.. Publicado em: 02/12/2019
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23. Isolation of erythrinan alkaloids from the leaves and flowers of Erythrina speciosa
Abstract In this paper, we describe the extraction of three alkaloids from the leaves and flowers of Erythrina speciosa, a plant documented in the literature to possess a range of potential medicinal applications. Two alkaloids were isolated from both leaves and flowers, with erythrartine being isolated from both plant parts. In agreement with the literature
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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24. GC–MS and LC–MS/MS workflows for the identification and quantitation of pyrrolizidine alkaloids in plant extracts, a case study: Echium plantagineum
Abstract Workflows based on gas and liquid chromatography coupled to mass spectrometry for the identification of toxic pyrrolizidine alkaloids present in plants were developed and applied to Echium plantagineum L., Boraginaceae, extracts. GC–MS based determinations need reduction and derivatization steps prior to MS analysis, which is performed using a Ful
Rev. bras. farmacogn.. Publicado em: 17/10/2019