Adrenal Glands
Mostrando 13-24 de 176 artigos, teses e dissertações.
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13. Estudo da proteína P450 óxido-redutase e dos citocromos hepáticos 2C19 e 3A4 como possíveis moduladores do fenótipo da deficiência da 21-hidroxilase / Study of P450 oxidoreductase protein and hepatic cytochromes 2C19 and 3A4 as a potential modulatory factors in 21-hydroxylase deficiency phenotype
A deficiência da 21-hidroxilase é uma doença genética comum, causada por mutações no gene CYP21A2, que codifica a enzima 21-hidroxilase (P450c21). A deficiência da 21-hidroxilase afeta a síntese de cortisol e aldosterona e promove acúmulo de precursores, que são desviados para a síntese de andrógenos. Observa-se três principais fenótipos: a for
Publicado em: 2009
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14. Síntese, análise, purificação e biodistribuição em modelo animal do Radiofármaco 177Lu3+-dotatato para uso diagnóstico e terapêutico em tumores neuroendócrinos / SYNTHESIS, ANALYSIS, PURIFICATION AND BIODISTRIBUTION IN AN ANIMAL MODEL OF RADIOPHARMACEUTICAL 177Lu3+- DOTATATO FOR DIAGNOSTIC AND THERAPEUTIC USE IN NEUROENDOCRINE TUMORS
The aim of this work was to propose rationalization in the synthesis, analysis and purification of radiopharmaceutical 177Lu3+-DOTATATO for diagnostic and therapeutic use in neuroendocrine tumors, as well as for evaluating biodistribution of this radiopharmaceutical in an animal-model. The complexation reaction for the synthesis of radiopharmaceutical was ca
Publicado em: 2009
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15. Análise da ação do ACTH e do peptídeo N-terminal da POMC na proliferação, morte celular e na expressão das proteínas de genes de resposta secundária na supra-renal de ratos hipofisectomisados ou tratados com dexametasona. / Analysis of ACTH and the peptide N-terminal POMC in proliferation, cell death, and expression of secondary response genes in adrenal glands of hypophysectomized or dexamethasone treated rats.
Different experimental models have been used to study the trophic action of ACTH in adrenal, which seems to be important in proliferation and cell death in vivo. This hypothesis was tested using hypophysectomized or dexamethasone treated rats, and through IHC we evaluate: 1-the BrdU incorporation in different adrenal cortex zone after i.p. of ACTH, FGF2 or N
Publicado em: 2008
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16. Avaliação da resposta inflamatória pulmonar e do transporte mucociliar em modelo de inflamação alérgica pulmonar: modulação pelo estresse induzido pela natação forçada / Evaluation of pulmonary inflammatory responses and mucociliary transport in a model of chronic allergic inflammation: modulation by stress induced by forced swimming
Background: It has increasing evidence linking the role of stress in the onset of asthma exacerbation and in the maintenance of asthmatic crises, as well as the importance of mucus production and the mucociliary clearance in the asthma physiopathology. Objectives: So, we consider relevant to evaluate in guinea pigs with pulmonary chronic allergic inflammatio
Publicado em: 2008
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17. Inhibition mechanism of the nicotinic acetylcholine receptor α3β4 tacrine / Mecanismos de inibição do receptor nicotínico de acetilcolina α3β4 pela tacrina
Neuronal nicotinic acetylcholine (cholinergic) receptors (nAChRs) are integral membrane proteins and belong to the family of ligand-gated cation channels composed by α and β subunits. These receptors play a key role in the signal transmission between neurons in the central and peripheral nervous system. The α3β4 subtype, for example, is t
Publicado em: 2008
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18. Association study between a genetic polymorphism in aldosterone sinthase and resistance to anti-hypertension treatment / Estudo de associação entre polimorfismo no gene da aldosterona sintase e resistencia ao tratamento anti-hipertensivo
Introduction: Resistant hypertension is characterized by elevated blood pressure concurrent with the use of 3 different anti-hypertensive drugs, being one of them a diuretic. There are genetic factors that interfere in the arterial pressure control system and may have a significant role in resistant hypertension. Renin-Angiotensin-Aldosterone System plays a
Publicado em: 2008
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19. Bilateral afrenal nodules due to histoplasmosis in an elderly
We report a case history of an 84-year-old elderly male patient that presented with a clinical picture suggestive of adrenal failure and bilateral adrenal nodules detected by abdominal computed tomography. A fine needle-guided biopsy was inconclusive for achieving a final diagnosis. The patient died due to septic shock and the autopsy disclosed histoplasmosi
Brazilian Journal of Infectious Diseases. Publicado em: 2007-02
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20. Search of prostatic tissue in 46,XX congenital adrenal hyperplasia patients / Pesquisa de tecido prostático em pacientes 46,XX portadoras da forma clássica de hiperplasia congênita das supra-renais
Introduction: The presence of prostatic tissue in 46,XX congenital adrenal hyperplasia (CAH) patients has already been reported. The development of this tissue is due to androgenic stimulation in Skenes paraurethral glands by dihydrotestosterone. These glands have histological and enzymatic homology with the prostate. So far, two cases with alterations of pr
Publicado em: 2007
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21. Comprometimento Adrenal na Paracoccidioidomicose: Estudo Clínico, Laboratorial e por Tomografia Computadorizada / Commitment adrenal in Paracoccidioidomycosis: Clinical study, laboratory and by computed tomographic
Paracoccidioidomicose, micose sistêmica endêmica no Brasil, particularmente na sua forma crônica do adulto, é causa freqüente de comprometimento das glândulas adrenais, podendo levar à insuficiência adrenal crônica primária (doença de Addison). O objetivo deste trabalho foi reavaliar os pacientes com diagnóstico de paracoccidiodomicose e diagnós
Publicado em: 2007
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22. Herpesvirus simplex Type 1 (HSV-1) in marmosets (Callithrix jacchus and Callithrix penicillata) - Pathological and molecular characterization / Herpesvirus simplex Tipo 1 (HSV-1) em sagüis (Callithrix jacchus e Callithrix penicillata) - Caracterização anatomopatológica e molecular
The introduction of wild animals in the conviviality with humans represents serious risk to the health of both. The objective of this work was to prove the hypothesis of the HSV-1 is the agent of vesicular and ulcerative lesion in the skin and mucous membranes, associated with neurological signs observed in marmosets in Brazil. Six white-tufted-ear marmosets
Publicado em: 2007
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23. Hiperplasia congenita das supra-renais por deficiencia da 21-hidroxilase : crescimento e composição corporal de crianças com a forma classica, variante perdedora de sal / Congenital adrenal hyperplasia due to 21-hydroxylase deficiency : growth and body composition of children with salt wasting classification
o objetivo do presente estudo foi avaliar o crescimento e a composição corporal de crianças com Hiperplasia Congênita das Supra-renais. Foram incluídas no estudo 21 crianças pré-puberes (8M/I3F) entre 2,1 e 10,2 anos de idade, portadoras de Hiperplasia Congênita das Supra-renais por deficiência de 21-hidroxilase forma clássica perdedora de sal, que
Publicado em: 2007
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24. Primary hydatid disease in the adrenal gland: a case report
Hydatid cysts may be found in almost any part of the body, but most often they are found in the liver and lungs. Other organs that are occasionally affected include the brain, muscle, kidney, heart, pancreas, and adrenal and thyroid glands. We report a case of hydatid cyst of the adrenal gland.
Brazilian Journal of Infectious Diseases. Publicado em: 2006-10