Adrenal Function
Mostrando 13-24 de 222 artigos, teses e dissertações.
-
13. Neural regulation of the stress response: glucocorticoid feedback mechanisms
The mammalian stress response is an integrated physiological and psychological reaction to real or perceived adversity. Glucocorticoids are an important component of this response, acting to redistribute energy resources to both optimize survival in the face of challenge and to restore homeostasis after the immediate challenge has subsided. Release of glucoc
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-04
-
14. Molecular mechanisms of RET receptor-mediated oncogenesis in multiple endocrine neoplasia 2
Multiple endocrine neoplasia type 2 is an inherited cancer syndrome characterized by tumors of thyroid and adrenal tissues. Germline mutations of the REarranged during Transfection (RET) proto-oncogene, leading to its unregulated activation, are the underlying cause of this disease. Multiple endocrine neoplasia type 2 has been a model in clinical cancer gene
Clinics. Publicado em: 2012
-
15. Variable clinical expression in patients with a germline MEN1 disease gene mutation: clues to a genotype-phenotype correlation
Multiple endocrine neoplasia type 1 is an inherited endocrine tumor syndrome, predominantly characterized by tumors of the parathyroid glands, gastroenteropancreatic tumors, pituitary adenomas, adrenal adenomas, and neuroendocrine tumors of the thymus, lungs or stomach. Multiple endocrine neoplasia type 1 is caused by germline mutations of the multiple endoc
Clinics. Publicado em: 2012
-
16. Estudo dos efeitos da exposição materna à nicotina na lactação sobre a função da medula adrenal e dos adipócitos de ratos machos e fêmeas / Programming of the adrenal function and leptin production by nicotine exposure during lactation: gender differences in rats
Alterações nutricionais, hormonais e ambientais nos períodos críticos do desenvolvimento como a gestação e/ou lactação podem influenciar a estrutura e a fisiologia de órgãos e tecidos, predispondo ao aparecimento de doenças na vida adulta. Esse fenômeno é conhecido como programação metabólica. O fumo materno na gestação/lactação tem sido
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/02/2011
-
17. Early life stress, HPA axis, and depression
Considerable evidence from various studies suggests a preeminent role for early adverse experiences in the development of psychopathology, especially depression. The most recent studies reviewed herein suggest that early life stressors are associated with an increased risk for mood disorders in adulthood. This review examines the emerging literature on the r
Psychology & Neuroscience. Publicado em: 2011
-
18. Maternal undernutrition and the offspring kidney: from fetal to adult life
Maternal dietary protein restriction during pregnancy is associated with low fetal birth weight and leads to renal morphological and physiological changes. Different mechanisms can contribute to this phenotype: exposure to fetal glucocorticoid, alterations in the components of the renin-angiotensin system, apoptosis, and DNA methylation. A low-protein diet d
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-11
-
19. Expression of mdr isoforms in mice during estrous cycle and under hormone stimulation
The multidrug resistance (MDR) phenotype is associated with the expression of P-glycoprotein (Pgp), coded by the multigenic mdr family. Mice present the isoforms mdr1 and mdr3, which are responsible for multidrug resistance, and mdr2, that is involved in the transport of phospholipids. mdr1 expression has more recently been associated also with the secretion
Publicado em: 2010
-
20. Comparação de duas doses do teste ACTH para diagnóstico de insuficiência de corticoesteróides durante choque séptico em crianças
Objetivo: Revisar a literatura sobre insuficiência corticosteróide em choque séptico incluindo sua definição, quadro clínico, diagnóstico e tratamento. Após isso, objetivamos comparar os resultados do teste diagnóstico de estimulação adrenal com ACTH 1 mcg/ 1,73m2 em relação ao teste em dose padrão atualmente mais utilizado na literatura (250 m
Publicado em: 2009
-
21. Influência de fatores individuais e sociais sobre as respostas endócrina e comportamental de callithrix jacchus a desafios ambientais físicos e sociais
Regarding the growing number of human beings with physical and mental pathologies associated to different stressor agents, attempts are being made to validate animal models with a close phylogenetic resemblance to man, to study stress response. Callithrix jacchus has been widely used in biomedical research, including on stress, but there is scarce informatio
Publicado em: 2009
-
22. Estudo do sistema neuroimunoendócrino na caquexia neoplásica e da resposta ao tratamento com esteróides
The anorexia-cachexia syndrome (ACS), of multifactorial source and complex, is common in chronic diseases, like advanced cancer. Is associated with weight loss and decrease food intake, sometimes causing death. The objective of the present study was to evaluate the influence of neoplastic cachexia over the hypothalamus-pituitary-adrenal axis and immune syste
Publicado em: 2008
-
23. Efeitos da exposição pré-púbere ao herbicida glifosato no desenvolvimento reprodutivo de ratos Wistar machos / Effects of the prepubertal exposure to glyphosate herbicide on reproductive development of male Wistar rats
The glyphosate-Roundup is a widely pesticide used in several culturas agrícolas. Its reproductive toxicity is associated to inhibition of StAR protein and aromatase enzime that cause in vitro significantly reduction in testosterone and estradiol production. The objective of this study was to evaluate the in vivo effects of inhibition of StAR protein and aro
Publicado em: 2007
-
24. Repercussões sistêmicas da orquiectomia bilateral, em ratos
This investigation belongs to a line of research, and its purpose was to evaluate the effects of hypogonadism secondary to orchiectomy on the organism of rats. 178 male Wistar rats were used. Of these, 54 were young (Y) and 124 were mature (M). These animals were divided into the following groups: Group 1 control, animals submitted only to incision and sutur
Publicado em: 2007