Adenoid Cystic Carcinoma
Mostrando 13-24 de 48 artigos, teses e dissertações.
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13. Estudo da angiogenese em carcinomas salivares com e sem diferenciação mioepitelial / Angiogenesis in salivary carcinomas with and without myoepithelial differentiation
To investigate whether salivary carcinomas with and without myoepithelial differentiation could present differences regarding degree of angiogenesis, we compared tumor vascularization between adenoid cystic (31 cases) and epithelial- myoepithelial carcinomas (14) versus mucoepidermoid (37) carcinoma. The expression of peroxiredoxin I was also studied to veri
Publicado em: 2009
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14. Adesão e atividade de protease são reguladas pelo peptídeo derivado da laminina AG73, sindecan-1 e integrina 1 em linhagem celular derivada de carcinoma adenóide cístico / Ahesion and protease activity are regulated by the laminin-derived peptide AG73, syndecan-1 and bintegrin in cell line derived from adenoid cystic carcinoma.
We studied induction of MMP activity by b1-laminin peptide AG73 in adenoid cystic carcinoma cell line (CAC2). Cells grown inside AG73-enriched laminin-111 exhibited pseudocystics spaces. MMP inhibitor decreased those spaces, suggesting MMPs action. Cells grown on AG73 showed a dose-dependent increase of MMP9 secretion. MMP9 siRNAi decreased remodeling in 3D
Publicado em: 2009
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15. Laminin peptide C16 regulates migration, invasion and protease activity of adenoid cystic carcinoma cells through integrins, AKT and ERK. / Peptídeo C16 derivado da laminina regula migração, invasão e secreção de protease em linhagem celular derivada de carcinoma adenóide cístico humano através de integrinas e das vias de sinalização AKT e ERK.
Avaliamos a capacidade de indução de migração, invasão e secreção de protease pelo peptídeo derivado da laminina, C16 (KAFDITYVRLKF, cadeia g1) em linhagem celular (CAC2) de carcinoma adenóide cístico humano. Laminina g1 foi imunolocalizada no carcinoma adenóide in vivo e in vitro. Ensaio de ferida, em câmara bipartite e em vídeo microscopia (ti
Publicado em: 2009
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16. Estudo retrospectivo de 3091 casos de neoplasias epiteliais primarias de glandulas salivares maiores e menores intra-orais / Retrospective study of 3091 cases of primary epithelial salivary gland tumors involving the major and minor glands
The aim of this study was to analyse retrospectively the histological and epidemiological characteristics of 3091 cases of intraoral primary epithelial neoplasms of the minor and major salivary glands. It was included on this study, 1766 cases from Brazil, 544 from the U.S., 405 from Uruguay, 151 from Peru, 134 from Guatemala and 91 from Mexico. Benign tumor
Publicado em: 2009
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17. Measurement of annexin V uptake and lactadherin labeling for the quantification of apoptosis in adherent Tca8113 and ACC-2 cells
Phosphatidylserine (PS) exposure occurs during the cell death program and fluorescein-labeled lactadherin permits the detection of PS exposure earlier than annexin V in suspended cell lines. Adherent cell lines were studied for this apoptosis-associated phenomenon to determine if PS probing methods are reliable because specific membrane damage may occur duri
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-09
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18. c-Jun and junB immunoprofile in adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma of salivary glands / Estudo da imunoexpressão das proteínas C-JUN e JUNB em carcinoma adenóide cístico e adenocarcinoma polimorfo de baixo grau de malignidade de glândulas salivares
Adenoid cystic carcinoma and polymorphous low grade are salivary gland neoplasms. ACC can arise in both, major or minor salivary glands. However, Polymorphous lowgrade adenocarcinoma, occurs specifically in minor salivary glands dispersed in the oral cavity. They share many common histologic features, as infiltrating solid, tubular and cribiform patterns and
Publicado em: 2008
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19. Alterations of E-cadherin and β-catenin genes in pleomorphic adenoma and adenoid cystic carcinoma: molecular and immunohistochemical study / Alterações nos genes da E-caderina e β-catenina em adenoma pleomórfico e carcinoma adenóide cístico: estudo molecular e imuno-histoquímico
Pleomorphic adenoma and adenoid cystic carcinoma represent a benign and malignant salivary gland neoplasm, respectively, that shares the same histological origin, however with distinct biological behavior. The aim of the present study was identify the -160 C/A polymorphism in the gene CDH1, mutational analysis of CTNNB1 gene and evaluation the expression of
Publicado em: 2008
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20. Estudo da expressão imunoistoquímica da proteína galectina-3 associada à -catenina e ciclina D1 em carcinoma adenóide cístico e adenocarcinoma polimorfo de baixo grau de malignidade de glândulas salivares / Differential expression of galectin-3, -catenin and cyclin D1 in adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma of salivary glands
Neoplasias malignas das glândulas salivares são lesões raras e o mecanismo pelo qual esses tumores progridem ainda não está completamente esclarecido na literatura. A galectina-3 é uma proteína multifuncional expressa em uma grande quantidade de tecidos normais, mas que também tem sido associada à progressão tumoral de neoplasias malignas da tireó
Publicado em: 2008
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21. Estudo clínico-epidemiológico de neoplasias de glândula salivar menor no estado da Bahia. / Intraoral menor salivary gland tumors in a Brazilian population: a retrospective study
Minor salivary gland tumors are relatively rare and comprise a diverse group of neoplasms exhibiting complex morphology. The aim of this study was to investigate the clinical and epidemiological features of the minor salivary gland tumors diagnosed at Aristides Maltez Hospital, Salvador, Bahia, between 1976 and 2007. Data regarding the age and sex distributi
Publicado em: 2008
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22. Avaliação do potencial metastático e da vascularização nas neoplasias epiteliais de glândulas salivares.
Tumoral angiogenesis represents a potential bimolecular marker for prognosis and predictive factor for metastasis in human solid tumors. Recently, endothelial markers and growth vascular factors such as the vascular endothelial growth factor (VEGF) and the platelet derived endothelial growth factor (PDEGF), as well as the vascular endothelial markers CD34 an
Publicado em: 2007
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23. Prognostic factors in salvage surgery for recurrent salivary gland carcinoma / Fatores prognósticos em carcinomas de glândulas salivares recidivados submetidos à cirurgia de resgate
Salivary gland carcinomas are rare and the main treatment option is surgery with or without postoperative radiotherapy. Almost half of the cases present recurrences of tumors and the majority are local. The only potentially curative treatment for recurrent tumors is salvage surgery. However, few papers were published on this subject. The aim of this study is
Publicado em: 2007
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24. Predictive factors and prognostic importance of limph node metastasis in salivary gland carcionomas / Fatores preditivos e importancia prognostica das metastases linfonodais em carcinomas das glandulas salivares
Benign and malignant salivary gland neoplasias comprises 4?10% of all the neoplasias affecting humans. The parotid glands are the most commonly affected, followed by minor salivary and submandibular glands. Regional metastasis, tumor extension, presence of pain, and age older than 55 years have been considered poor prognostic indicators. The aim of this stud
Publicado em: 2007