Adenohypophysis
Mostrando 13-24 de 32 artigos, teses e dissertações.
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13. Ontogeny of the prohormone convertases PC1 and PC2 in the mouse hypophysis and their colocalization with corticotropin and alpha-melanotropin.
In the adult pituitary, anterior lobe corticotrophs and intermediate lobe melanotrophs differentially process proopiomelanocortin (POMC). Within the corticotrophs, POMC is processed mainly to corticotropin (ACTH) and beta-lipotropin, while alpha-melanotropin (alpha MSH) and beta-endorphin are the major end products in the melanotrophs. The observed transient
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14. Further observations on the pharyngeal hypophysis and the postsphenoid in the mature male rat.
In an investigation into the pharyngeal hypophysis and the postsphenoid using seven hypophysectiomized mature male rats, a pharyngeal hypophysis and a craniopharyngeal canal was found in each of two rats. Cellular differentiation was noted in the pharyngeal hypophysis in both rats. In one rat the pharyngeal hypophysis was markedly larger than any seen to dat
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15. Incorporation of tritiated thymidine in the hypophysis of the rhesus monkey (Macaca mulatta) embryo.
Proliferation and growth in the neurohypophysis and adenohypophysis, including the pars distalis, pars intermedia and pars tuberalis, were studied in a series of rhesus monkey embryos of stages 13 to 21 (from 26 to 41 days of gestation) and labelled for one hour with a single intrachorionic injection of 3H-thymidine. As early as stage 13 the anlage of the ne
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16. Follicles and related structures in the pars intermedia of the adenohypophysis of the jird (Meriones unguiculatus).
Two types of follicle composed of non-granulated cells are regularly found in the pars intermedia of the mature jird (Meriones unguiculatus). A few (Type I) are large and cystic with a flattened epithelium bearing some microvilli, but most (Type II) are small and irregular in shape with a cuboidal to low columnar epithelium bearing many microvilli. They are
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17. Seasonal changes in the ultrastructure of the thyrotroph in the wookchuck (Marmota monax) adenohypophysis.
Throtrophs of the woodchuck anterior pituitary are described through the four seasons of the year. Evidence of an increase in number and activity in the spring is presented. Activity of the thyrotroph is seen to continue through the summer and decline in the autumn to quiescence during the hibernatory period of winter. The significance of these findings is d
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18. Human gamma-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis.
The amino acid sequence of human gamma-trace, a basic microprotein without known function, was determined by automated Edman degradations of the carboxymethylated polypeptide chain and of fragments obtained by cyanogen bromide treatment and tryptic digestion after blocking of lysine residues. The single polypeptide chain contained 120 residues, and the calcu
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19. Regional distribution of putative vasopressin receptors in rat brain and pituitary by quantitative autoradiography.
Quantitative light microscopic autoradiography was used to map and characterize the distribution of [3H]arginine vasopressin [( 3H]AVP) binding sites in the rat brain. HPLC analysis for possible degradation of AVP during binding indicated that addition of specific peptidase inhibitors prevented metabolism of AVP. Binding sites for [3H]AVP were observed in th
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20. Expression of guanylin in “pars tuberalis-specific cells” and gonadotrophs of rat adenohypophysis‖
The intestinal peptide guanylin regulates the electrolyte/water transport in the gastrointestinal epithelium by paracrine/luminocrine mechanisms. Because guanylin also circulates in the blood, we investigated the rat hypothalamo-pituitary region for expression and cellular localization of this peptide. Reverse transcriptase–PCR analyses with guanylin-speci
The National Academy of Sciences.
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21. Aspects of the human pharyngeal hypophysis in normal and anencephalic fetuses and neonates and their possible significance in the mechanism of its control.
Aspects of the pharyngeal hypophysis in normal and anencephalic human fetuses and neonates have been described. Volumetric and histological changes in the normal gland similar to those observed previously in the adult are noted. The sellar and pharyngeal hypophyses develop in parallel during intrauterine life, but the latter has reached its maximum developme
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22. Quantitation of proenkephalin A messenger RNA in bovine brain, pituitary and adrenal medulla: correlation between mRNA and peptide levels.
Concentrations of mRNA coding for the opioid peptide precursor proenkephalin A were measured in bovine brain areas, pituitary and adrenal medulla. In all tissues, a single hybridizable species of 1400 bases in size was found by Northern blot analysis using as a probe a single-stranded (ss) cDNA complementary to bovine proenkephalin A mRNA. In solution hybrid
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23. Stimulation of Adenosine 3′:5′-Cyclic Monophosphate Accumulation in Anterior Pituitary Gland In Vitro by Synthetic Luteinizing Hormone-Releasing Hormone
A near-maximal dose (20 ng/ml) of synthetic luteinizing hormone(LH)-releasing hormone/follicle-stimulating hormone(FSH)-releasing hormone added to incubated anterior pituitary tissue of male rats leads to concomitant increases of intracellular concentrations of adenosine 3′:5′-monophosphate and of release of both LH and FSH. The stimulatory effect of LH-
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24. Ascorbic acid stimulates gonadotropin release by autocrine action by means of NO
Because high concentrations of ascorbic acid (AA) are found in the adenohypophysis, we hypothesized that it might have an acute effect on the secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the gland, particularly because we have reported that AA rapidly inhibits stimulated LH-releasing hormone (LHRH) release from media
The National Academy of Sciences.