Action For Insult
Mostrando 1-10 de 10 artigos, teses e dissertações.
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1. Ação do inibidor da enzima dipeptidil peptidase 4 sobre o pré-condicionamento isquêmico em pacientes portadores de diabetes mellitus tipo 2 e doença arterial coronariana estável / Effect of dipeptidyl peptidase-4 enzyme inhibitor on ischemic preconditioning in patients with type 2 diabetes and symptomatic coronary artery disease
Ischemic preconditioning (IPC) refers to the phenomenon in which short periods of myocardial ischemia and reperfusion promote resistance to a subsequent prolonged ischemic insult. Some hypoglycemic drugs, such as glibenclamide and repaglinide, are able to inhibit this protective phenomenon probably by its effects as blockers of adenosine triphosphate-depende
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/10/2012
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2. Validation of the anti-bacteremic efficacy of an essential oil rinse in a Brazilian population: a cross-over study
This cross-over study was conducted to assess the germ-killing efficacy of an essential oil mouthrinse (EOM) by determining the blood levels of microorganisms associated with induced bacteremia and investigating the prevalence of this event in Brazilians with mild-to-moderate gingivitis. Thirty four (31.19%) subjects positive for bacteremia induced by chewin
Braz. oral res.. Publicado em: 28/08/2012
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3. Esclerosis lateral amiotrófica esporádica: nueva hipótesis relacionada con su etiología y patogenia que sugiere que los astrocitos podrían ser el blanco primario alojando un agente nocivo aun desconocido
This article briefly describes the already known clinical features and pathogenic mechanisms underlying sporadic amyotrophic lateral sclerosis, namely excitoxicity, oxidative stress, protein damage, inflammation, genetic abnormalities and neuronal death. Thereafter, it puts forward the hypothesis that astrocytes may be the cells which serve as targets for th
Arquivos de Neuro-Psiquiatria. Publicado em: 2011-08
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4. ACTION FOR INSULT: A PROCEDURAL MECHANISM OF THE EUROPEAN UNION INSPIRING THE PROCESS OF THE MERCOSUL / AÇÃO POR INCUMPRIMENTO: UM MECANISMO PROCESSUAL DA UNIÃO EUROPÉIA INSPIRANDO O PROCESSO DO MERCOSUL
This work presents the problematic one of the adoption of the action for insult, one of the procedural mechanisms of communitarian justice, in the Latin American right of the Mercosul. For the resolution of the situation problem it was looked to stand out the main characteristics of the European Union and the Mercosul, main with respect to the current struct
Publicado em: 2008
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5. Effects of exogenous free radicals on electromechanical function and metabolism in isolated rabbit and guinea pig ventricle. Implications for ischemia and reperfusion injury.
Oxygen-derived free radicals have been implicated in the pathogenesis of cardiac dysfunction during ischemia, postischemic myocardial "stunning," and reperfusion injury. We investigated the effects of oxygen-derived free radicals on cardiac function in intact isolated rabbit hearts and single guinea pig ventricular myocytes. In the intact rabbit ventricle, e
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6. Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury
Erythropoietin (EPO) plays an important role in the brain's response to neuronal injury. Systemic administration of recombinant human EPO (rhEPO) protects neurons from injury after middle cerebral artery occlusion, traumatic brain injury, neuroinflammation, and excitotoxicity. Protection is in part mediated by antiapoptotic mechanisms. We conducted parallel
National Academy of Sciences.
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7. Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke
Insulin-like growth factors I and II (IGF-I and IGF-II) play an important role in normal growth and brain development and protect brain cells from several forms of injury. The effects of IGFs are mediated by type-I and type-II receptors and modulated by potentially six specific binding proteins that form high-affinity complexes with IGFs in blood and cerebro
The National Academy of Sciences.
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8. Disruption of Sur2-containing KATP channels enhances insulin-stimulated glucose uptake in skeletal muscle
ATP-sensitive potassium channels (KATP) are involved in a diverse array of physiologic functions including protection of tissue against ischemic insult, regulation of vascular tone, and modulation of insulin secretion. To improve our understanding of the role of KATP in these processes, we used a gene-targeting strategy to generate mice with a disruptio
The National Academy of Sciences.
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9. Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced death
Transient global or forebrain ischemia induced experimentally in animals can cause selective, delayed neuronal death of hippocampal CA1 pyramidal neurons. A striking feature is a delayed rise in intracellular free Zn2+ in CA1 neurons just before the onset of histologically detectable cell death. Here we show that α-amino-3-hydroxy-5-methyl-4-isoxazolepropio
National Academy of Sciences.
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10. Fibroblast growth factors: An epigenetic mechanism of broad spectrum resistance to anticancer drugs
Based on the observation that removal of tumors from metastatic organs reversed their chemoresistance, we hypothesized that chemoresistance is induced by extracellular factors in tumor-bearing organs. By comparing chemosensitivity and proteins in different tumors (primary vs. metastases) and different culture systems (tumor fragment histocultures vs. monolay
The National Academy of Sciences.