Acetyl Tetrapeptide 5
Mostrando 1-5 de 5 artigos, teses e dissertações.
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1. Application of peptides in cosmetics: development of formulations, stability and efficacy / Aplicação de peptídeos em cosméticos: desenvolvimento de formulações, estabilidade e eficácia
The aim of this study was the development, evaluation of the stability and the efficacy of cosmetic formulations containing acetyl hexapeptide-3 (AHP), or acetyl tetrapeptide-5 (ATP) or mixture of di- and peptides (DTP). For this purpose the 6 following formulations (F) were developed: F1- containing hydroxyethyl cellulose (HEC), methylphenyl polysiloxane (M
Publicado em: 2008
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2. A microsomal endoprotease that specifically cleaves isoprenylated peptides.
A microsomal enzymatic activity is described that can specifically cleave the tetrapeptide N-acetyl-S-farnesyl-L-Cys-L-Val-L-Ile-L-Ser between the isoprenylated cysteine residue and the valine residue. Km and Vmax values are measured as 5.8 microM and 251 pmol/min per mg of protein, respectively. Proteolytic cleavage of the substrate is stereospecific becaus
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3. Acute angiotensin-converting enzyme inhibition increases the plasma level of the natural stem cell regulator N-acetyl-seryl-aspartyl-lysyl-proline.
Angiotensin I-converting enzyme (ACE) has two homologous active NH2- and COOH-terminal domains and displays activity toward a broad range of substrates. The tetrapeptide N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) has been shown to be hydrolyzed in vitro by ACE and to be a preferential substrate for its NH2-terminal active site. This peptide is a regulat
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4. The carbohydrates of mouse hepatitis virus (MHV) A59: structures of the O-glycosidically linked oligosaccharides of glycoprotein E1.
Two size classes of O-glycosidically linked oligosaccharides were liberated from glycoprotein E1 of mouse hepatitis virus (MHV) A59 by reductive beta-elimination and separated by h.p.l.c. The structures of the reduced oligosaccharides were determined by successive exoglycosidase digestions and by methylation analyses involving combined capillary gas chromato
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5. Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers
Hepsin is a membrane-anchored, trypsin-like serine protease with prominent expression in the human liver and tumours of the prostate and ovaries. To better understand the biological functions of hepsin, we identified macromolecular substrates employing a tetrapeptide PS-SCL (positional scanning-synthetic combinatorial library) screen that rapidly determines
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