Accelerated Stability Studies
Mostrando 1-12 de 30 artigos, teses e dissertações.
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1. EXTRACT OF Punica granatum L.: AN ALTERNATIVE TO BHT AS AN ANTIOXIDANT IN SEMISSOLID EMULSIFIED SYSTEMS
Pomegranate (Punica granatum L.) is a fruit which has important pharmacological activities and has been attracting attention due to its important antioxidant activity, a significant feature in relation to cosmetics. Formulations containing different concentrations of an ethanolic extract of pomegranate (0.1, 1.0 and 5.0%) (w/w) as an antioxidant agent showed
Quím. Nova. Publicado em: 2017-01
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2. Development of an oral suspension containing dry extract of Aleurites moluccanus with anti-inflammatory activity
Abstract Aleurites moluccanus L. (Willd.), Euphorbiaceae, is a tree that is native to Indonesia and India. Various parts of this tree are commonly used in traditional medicine to treat pain, fever, inflammation, hepatitis, gastric ulcer and other ailments. An oral suspension containing dried extract of A. moluccanus was developed and in vivo anti-inflammator
Rev. bras. farmacogn.. Publicado em: 2016-02
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3. Simultaneous determination of four phenolic compounds in extracts of aerial parts of Ipomoea pes-caprae (L.) R. Br. (Convolvulaceae) by HPLC-UV
Among other applications, Ipomoea pes-caprae is popularly used to treat jellyfish stings, supporting the development of a product for dermatological use. Hydroethanolic spray-dried extract was chosen for the further development of phytomedicines, and a stability-indicative HPLC-UV method was developed and validated for the determination of isoquercitrin and
Quím. Nova. Publicado em: 2014
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4. Hydroalcoholic extracts of Vellozia squamata: study of its nanoemulsions for pharmaceutical or cosmetic applications
Some species of plants are notable for the wide range of biologically active constituents in their tissues. Chemical and pharmacological studies of Vellozia squamata Pohl, Velloziaceae, popularly known in Brasil as "canela-de-ema" are scarce, but showed the presence of di-and triterpenoid that may be of scientific interest. In the present study the hydroalco
Rev. bras. farmacogn.. Publicado em: 01/02/2013
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5. Effect of accelerated aging on the microhardness and color stability of flexible resins for dentures
Acrylic resins have been widely used due to their acceptable esthetics and desirable characteristics such as easy handling, good thermal conductivity, low permeability to oral fluids and color stability. Flexible resins were introduced on the market as an alternative to the use of conventional acrylic resins in the construction of complete and partial remova
Brazilian Oral Research. Publicado em: 2010-03
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6. Estudo da estabilidade e do perfil de liberação de comprimidos de maleato de enalapril e determinação da concentração plasmática em pacientes
The stability of a pharmaceutical formulation can be a major factor in assuring the quality of a drug product and, as a consequence, the efficacy of the treatment. Enalapril is an anti-hypertensive pro-drug that, after being absorbed, is hydrolised into enalaprilat, an agent responsible for blocking the conversion of angiotensin I into angiotensin II. Stabil
Publicado em: 2008
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7. Development of nanoemulsions containing passion fruit seed oil (Passiflora edulis) and lavender essential oil (Lavandula officinalis) and evaluation of its topical anti-inflammatory activity. / Desenvolvimento de nanoemulsões à base de óleo de maracujá (Passiflora edulis) e óleo essencial de lavanda (Lavandula officinalis) e avaliação da atividade antiinflamatória tópica
Nanotechnology is a phenomenon that applies to mainly all sectors of science and in the cosmetics area the high investment in this field has strengthened the idea that nanotechnology products offer real advantages to consumers. The growing demand of consumers and the advances in knowledge about production and stability of dispersed systems enable the develop
Publicado em: 2008
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8. Caracterização e análises do ascorbato de monometilsilanotriol em formulações cosméticas / Characterization and analysis of monomethylsilanetriol ascorbate in cosmetic formulations
The monomethylsilanetriol ascorbate( MSA) presents the same functional properties of vitamin C. Besides presents antioxidant and depigmentant activity, the monomethylsilanetriol ascorbate presents silanol in it chemical structure. The silanol is a privileged active ingredient for cosmetics because it essential for growth, development and regeneration of cuta
Publicado em: 2007
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9. DEVELOPMENT OF SEMI-SOLID PREPARATIONS CONTAINING EXTRACT OF Sphagneticola trilobata (L.) AND PRUSKI (Acmela brasiliensis, Wedelia paludosa) (ASTERACEAE), AND EVALUATION OF IN VIVO TOPICAL ANTIINFLAMMATORY ACTIVITY / DESENVOLVIMENTO DE PREPARAÇÕES SEMI-SÓLIDAS CONTENDO EXTRATO DE Sphagneticola trilobata (L.) Pruski (Acmela brasiliensis, Wedelia paludosa) (ASTERACEAE) E AVALIAÇÃO DA ATIVIDADE ANTIINFLAMATÓRIA TÓPICA IN VIVO
he development phytotherapeutic dosage forms requires a series of stages in order to obtain an efficient, safe, and high quality preparation. The Sphagneticola trilobata (L.) Pruski (Asteraceae) is a native plant of Brazil, which frequently grows in coastal regions and barren land. In Portuguese, it is popularly known as Pseudo-arnica, Margaridão, Picão da
Publicado em: 2006
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10. Tecnologia de obtenÃÃo de anti-retroviral à base de Mesilato de Nelfinavir
The Protease Inhibitors (PI) constitutes a powerful class of anti-retroviral drugs that changed the therapy and evolution of the infection by HIV. In March of 1997, a new drug of this class, the Nelfinavir Mesylate was approved by the Food and Drug Administration (FDA). Since then, it has been often used, separately or in association with Reverse Transcripta
Publicado em: 2005
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11. Validation of analytical methods for analysis and stability studies of anti-retrovirais in pharmaceutical preparations. / Validação de métodos para análise e estudos de estabilidade de anti-retrovirais em preparações farmacêuticas
The acquired immunodeficiency syndrome is characterized by causing physical and functional depletion of the organisms immune system, through the cytophatic infection of CD4+ cells. Several antiretroviral drugs has been developed and commercially made available. In order to assure the quality control of drugs it is necessary to develop and validate new anal
Publicado em: 2003
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12. ObtenÃÃo, caracterizaÃÃo e avaliaÃÃo microbiolÃgica de uma nova forma farmacÃutica contendo hidroquinona
Hydroquinone (HQ) is a drug reported to possess manifold biological activities, such as depigmenting, antimicrobial and antitumour properties. The PluronicLecithin Organogel (PLOme) is a phospholipidic microemulsion particularly implied when a high cutaneous permeability and systemic absorption of a drug is suitable. Once that HQ is highly unstable i
Publicado em: 2003