Absorption Anvisa
Mostrando 1-11 de 11 artigos, teses e dissertações.
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1. Evaluation of Major and Trace Elements in Medicinal Plants
This study presents the elemental concentration results obtained from 59 medicinal plants used in Brazil, determined by instrumental neutron activation analysis (INAA), inductively coupled plasma-optical emission spectrometry (ICP OES) and cold vapor atomic absorption spectrometry (CV AAS). The selected plant species were chosen from the Brazilian National A
J. Braz. Chem. Soc.. Publicado em: 2016-12
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2. Monitoramento ambiental de zinco em produtos agrícolas / Environmental monitoring of zinc in agricultural products
Large areas have been affected by heavy metals in concentrations which may pose environmental hazard. Due to increased industrial activity and highly technical agriculture, it becomes critical to monitor the levels of heavy metals in soil, because plants behave as a mechanism for transfer of contaminants from soil to higher levels of the food chain. Ingestio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/10/2012
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3. Determinação do perfil farmacocinético de anti-inflamatórios não hormonais aplicados à clinica / Determination of the pharmacokinetic profile of the non-steroidal anti-inflammatory drugs related with clinic outcomes
Objective: The present work aims to evaluation the pharmacokinetic profile of the diclofenac-cholestyramine (140mg capsule) and two pharmaceuticals formulations (100mg tablets and 50mg/m oral suspension) of nimesulide in healthy adult subjects related with clinic outcomes in the hepatic enzymes panel and platelet count. Method: The studies were open, randomi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/08/2011
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4. Lithium carbonate: atomic absortion spectrophotometry in bioequivalence and pediatric pattern of use. / Carbonato de lítio: utilização da espectrofotometria de absorção atômica em bioequivalência e perfil de uso na pediatria.
The ideal of this thesis is to benefit patients that use lithium, through two studies: (1) comparison of the bioavailability of two lithium formulations; and (2) investigation of lithium use in children and adolescents. In order to analyze the bioequivalence, healthy volunteers (N=24), of both genders, were treated with two lithium carbonate formulations (30
Publicado em: 2007
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5. Determination of chlorpropamide in plasma, using high-performance liquid chromatography coupled to tandem mass spectrometry (LC/MS/MS) and their application in a study of bioequivalence / Determinação de clorpropamida em plasma empregando empregando cromatografia liquida de alta eficiencia acoplada a espectrometria de massa sequencial (LC/MS/MS) e sua aplicação em um estudo de bioequivalencia
The relative bioavailability between two formulations of chlorpropamide was assessed on the dosage form tablet 250 mg, in healthy volunteers of both sexes. The study was conducted using an open, randomized, two-period crossover design with the 3-week washout interval. Thirty-six subjects were selected. The blood samples were collected at the time prior to do
Publicado em: 2007
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6. Avaliação da bioequivalência de comprimidos contendo 10 mg de cloridrato de ciclobenzaprina / Bioequivalence avaliation of tables contain 10 mg of cyclobenzaprine hydrochloride
Cyclobenzaprine is a centrally acting muscle relaxant that has similarity with a tricyclic antidepressant. The purpose of this study was to evaluate the bioequivalence of two brands of cyclobenzaprine 10 mg tablets in healthy volunteers. The procedure of bioequivalence between test product (Miosan®) and reference product (Flexeril®) was a randomized, open
Publicado em: 2006
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7. Estudo de bioequivalencia de duas formulações de cefadroxil - capsula (500mg) em voluntarios sadios de ambos os sexos
The objective of this study is to compare the bioequivalence of Cefadroxil- capsule 500 mg formulated by Apotex of Brazil Ltda (test formulation) and Cefamox by LaboratoryBristol-Myers Squibb (reference formulation) in volunteers of both sexes. This study was necessary for the commercialization of medicines. The study was conducted with a randomized two-peri
Publicado em: 2005
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8. Estudo de bioequivalencia de duas formulações de cefadroxil - capsula (500mg) em voluntarios sadios de ambos os sexos
The objective of this study is to compare the bioequivalence of Cefadroxil- capsule 500 mg formulated by Apotex of Brazil Ltda (test formulation) and Cefamox by LaboratoryBristol-Myers Squibb (reference formulation) in volunteers of both sexes. This study was necessary for the commercialization of medicines. The study was conducted with a randomized two-peri
Publicado em: 2005
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9. Estudo de bioequivalencia de duas formulações de cefadroxil - capsula (500mg) em voluntarios sadios de ambos os sexos
The objective of this study is to compare the bioequivalence of Cefadroxil- capsule 500 mg formulated by Apotex of Brazil Ltda (test formulation) and Cefamox by LaboratoryBristol-Myers Squibb (reference formulation) in volunteers of both sexes. This study was necessary for the commercialization of medicines. The study was conducted with a randomized two-peri
Publicado em: 2005
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10. Biodisponibilidade como parÃmetro de qualidade e sua importÃncia no registro de medicamentos / Biodisponibility as a quality pattern and its importance to the registration of medicines.
This work will discuss the bioavailability of drug, how it is changed and its importance as a quality pattern to the registration of medicines in Brazil. In this light, bioavailability will be previously conceptualized and discussed together with other topics relevant to the comprehension of this work. Bioavailability can be affected by both the patient cond
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/07/2004
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11. Estudo de bioequivalencia entre duas formulações farmaceuticas (comprimidos) contendo 20mg de Lisinopril, em voluntarios sadios de ambos os sexos
The aim of this study was to evaluate the bioequivalence between two formulations of lisinopril 20 mg. The test formulation was Lisinopril tablet 20 mg, manufactured by Medley S/A Indústria Farmacêutica (Iot # LlC 06/01-1; expiry date: june/03) and the reference formulation was Zestril@ tablet 20 mg, manufactured by Astra Zeneca (Iot # A03534; expiry date:
Publicado em: 2003