Aberrant Crypts
Mostrando 1-10 de 10 artigos, teses e dissertações.
-
1. Gum arabic and red propolis protecteting colorectal preneoplastic lesions in a rat model of azoxymethane
Abstract Purpose: To evaluate red propolis, gum arabic and L-lysine activity on colorectal preneoplastic lesions induced by azoxymethane (AOM). Methods: The study featured 4 control groups (I-IV) and 4 experimental groups (V-VIII), totaling 48 rats. Once a week for 2 weeks, animals on control groups received saline, while animals in experimental groups re
Acta Cir. Bras.. Publicado em: 28/02/2019
-
2. Effect of probiotics on the development of dimethylhydrazine-induced preneoplastic lesions in the mice colon
PURPOSE: To determine the effect of probiotics on the development of chemically induced (1, 2-dimethylhydrazine) colonic preneoplastic lesions, in mice. METHODS: The animals were divided into five groups. The control group was injected with carcinogen alone and the other groups also received probiotics (1- Lactobacillus delbrueckii UFV-H2b20; 2- Bifidobacter
Acta Cir. Bras.. Publicado em: 2013-05
-
3. Efficacy of geraniol but not of β-ionone or their combination for the chemoprevention of rat colon carcinogenesis
β-ionone (βI), a cyclic isoprenoid, and geraniol (GO), an acyclic monoterpene, represent a promising class of dietary chemopreventive agents against cancer, whose combination could result in synergistic anticarcinogenic effects. The chemopreventive activities of βI and GO were evaluated individually or in combination during colon carcinogenesis induced by
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-06
-
4. Efeito da fibra como alimento funcional na prevenção da incidência de focos de criptas aberrantes (FCA) no cólon de camundongos induzida por 1,2- dimetilhidrazina / Effect of fiber as a functional food in preventing the incidence of aberrant crypt foci (ACF) in colon of mice induced by 1,2-dimethylhydrazine
The use of healthy diets has been a great ally in the prevention and treatment of various diseases, including colorectal cancer (CRC), a disease that affects much of the world population, configuring it as a public health problem. Genetic and environmental factors are cited as the main causes of the CRC. Among the diet can highlight the environmental. The us
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/08/2010
-
5. Efeito da dieta hipercalÃrica e hiperlipÃdica na formaÃÃo de criptas aberrantes induzidas por azoximetano em mucosa cÃlica de ratos / Effect of a hypercaloric and hyperlipidic diet, rich in polyunsaturated fat, ω-3 and ω-9, aberrant crypt on formation in colonic mucosa, azoxymethane-induced in rats
O cÃncer colorretal (CCR) à a quinta neoplasia mais incidente no Brasil e sua freqÃÃncia vem aumentando em paÃses industrializados. A lesÃo prÃ-neoplÃsica mais precoce com presenÃa de displasia à o foco de cripta aberrante (FCA), estando relacionada como lesÃo precursora de adenomas colorretais e cÃncer em humanos. O entendimento destas lesÃes �
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/11/2008
-
6. Long-term aerobic swimming training by rats reduces the number of aberrant crypt foci in 1,2-dimethylhydrazine-induced colon cancer
We determined the effect of long-term aerobic swimming training regimens of different intensities on colonic carcinogenesis in rats. Male Wistar rats (11 weeks old) were given 4 subcutaneous injections (40 mg/kg body weight each) of 1,2-dimethyl-hydrazine (DMH, dissolved in 0.9% NaCl containing 1.5% EDTA, pH 6.5), at 3-day intervals and divided into three ex
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-11
-
7. Intrinsic denervation of the colon is associated with a decrease of some colonic preneoplastic markers in rats treated with a chemical carcinogen
Denervation of the colon is protective against the colon cancer; however, the mechanisms involved are unknown. We tested the hypothesis that the denervated colonic mucosa could be less responsive to the action of the chemical carcinogen dimethylhydrazine (DMH). Three groups of 32 male Wistar rats were treated as follows: group 1 (G1) had the colon denervated
Brazilian Journal of Medical and Biological Research. Publicado em: 14/02/2008
-
8. Efeitos da atividade física em marcadores biológicos da carcinogênese química do cólon de ratos Wistar / Physical activity effects on chemical colon carcinogenesis biomarkers in rats.
Estudos epidemiológicos vêm demonstrando que quantidades apropriadas de atividade física regular estão associadas a significativa redução do risco para o desenvolvimento de câncer de cólon em até 40% entre os indivíduos mais fisicamente ativos. Por outro lado, tem sido observado que o exercício físico exaustivo aumenta a produção sistêmica de
Publicado em: 2005
-
9. Aberrant crypt foci and colon cancer: comparison between a short- and medium-term bioassay for colon carcinogenesis using dimethylhydrazine in Wistar rats
Aberrant crypt foci (ACF) in the colon of carcinogen-treated rodents are considered to be the earliest hallmark of colon carcinogenesis. In the present study the relationship between a short-term (4 weeks) and medium-term (30 weeks) assay was assessed in a model of colon carcinogenesis induced by dimethylhydrazine (DMH) in the rat. Six-week-old male Wistar r
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-03
-
10. Feeding of soy protein isolate to rats during pregnancy and lactation suppresses formation of aberrant crypt foci in their progeny's colons: interaction of diet with fetal alcohol exposure
Soy protein isolate (SPI) in the diet may inhibit colon tumorigenesis. We examined azoxymethane (AOM)-induced aberrant crypt foci (ACF) in male rats in relation to lifetime, pre-weaning, or post-weaning dietary exposure to SPI and also within the context of fetal alcohol exposure. Pregnant Sprague Dawley rats were fed AIN-93G diets containing casein (20%, th
BioMed Central.