4 Nitroquinoline Noxide
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Antimutagenic activity of cashew apple (Anacardium occidentale Sapindales, Anacardiaceae) fresh juice and processed juice (cajuína) against methyl methanesulfonate, 4-nitroquinoline N-oxide and benzo[a]pyrene
Cashew apple juice (CAJ), produced from the native Brazilian cashew tree (Anacardium occidentale), and has been reported to have antibacterial, antifungal, antitumor, antioxidant and antimutagenic properties. Both the fresh unprocessed juice and the processed juice (cajuína in Portuguese) has been shown to consist of a complex mixture containing high concen
Genetics and Molecular Biology. Publicado em: 2008
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2. Ensaio cometa em microalgas marinhas: danos no DNA de Dunaliella tertiolecta Butcher 1959 causados pela exposição à 4-nitroquinolina-N-óxido e ao benzo [a] pireno / Comet assay in marine microalgae: DNA damage in Dunaliella tertiolecta Butcher 1959 caused by exposure to 4-nitroquinoline-N-oxide and benzo[a]pyrene
Dunaliella tertiolecta, uma alga verde fitoplanctônica de ampla distribuição no ambiente marinho, foi escolhida como organismo teste para estudar a possibilidade de ser utilizada no ensaio cometa, um teste de detecção de danos no DNA em células individualizadas muito utilizado na ecotoxicologia. Essas algas foram facilmente lisadas pela solução de li
Publicado em: 2007
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3. 2-(p-Nitrophenyl)-2'-deoxyadenosine, a new type of mutagenic nucleoside.
A crude preparation of 2-phenyladenosine was found to be mutagenic in the Ames Salmonella assay. In the purification of this preparation, it was revealed that 2-phenyladenosine itself was nonmutagenic but that 2-(m- and p-nitrophenyl)-adenosines (5m,p) contaminating the sample were the mutagenic principles. A structure-activity relationship study was carried
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4. The bZip Transcription Factor Cap1p Is Involved in Multidrug Resistance and Oxidative Stress Response in Candida albicans
Candida albicans is an opportunistic pathogenic yeast which frequently develops resistance to the antifungal agent fluconazole (FCZ) in patients undergoing long-term therapy. FCZ-resistant strains often display a reduced intracellular FCZ accumulation which correlates with the overexpression of the ATP-binding cassette transporters CDR1 and CDR2 or the major
American Society for Microbiology.