3 Diones
Mostrando 1-12 de 26 artigos, teses e dissertações.
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1. Synthesis and Biological Evaluation of Benzo[f]indole-4,9-diones N-Linked to Carbohydrate Chains as New Type of Antitumor Agents
In this work, we report the synthesis of three series of carbohydrate-based benzo[f]indole-4,9-diones and amino-1,4-naphthoquinone derivatives and evaluated their cytotoxic activity against eight human cancer cell lines. Several compounds showed a promising cytotoxic activity toward the tumor cell lines (half maximal inhibitory concentration (IC50) < 10.0 μ
J. Braz. Chem. Soc.. Publicado em: 2021-03
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2. Insulados e não democráticos: a (im)possibilidade do exercício da social accountability nos Tribunais de Contas brasileiros
Resumo Este artigo tem por objetivo analisar a permeabilidade dos Tribunais de Contas (TCs) brasileiros à sociedade, por meio de 3 perspectivas: a) transparência dos portais; b) transparência da atividade de fiscalização; e c) participação cidadã. Para tanto, foi estruturado um roteiro de observações, a partir de recomendações de organismos inter
Rev. Adm. Pública. Publicado em: 2020-04
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3. Improved Method for Microwave-Assisted Synthesis of Benzodiazepine-2,5-diones from Isatoic Anhydrides Mediated by Glacial Acetic Acid
An improved and simpler method for the synthesis of benzodiazepin-2,5-diones and 7-iodobenzodiazepin-2,5-diones catalyzed by glacial acetic acid using isatoic anhydride and 6-iodoisatoic anhydride, respectively, as starting materials is reported. The target products were achieved in good yields (up to 71%) using microwave irradiation as the activating mode o
J. Braz. Chem. Soc.. Publicado em: 2018-08
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4. Synthesis and Cytotoxic Evaluation of 1H-1,2,3-Triazol-1-ylmethyl-2,3-dihydronaphtho[1,2-b]furan-4,5-diones
ABSTRACT The 1,2-naphthoquinone compound was previously considered active against solid tumors. Moreover, glycosidase inhibitors such as 1,2,3-1H triazoles has been pointed out as efficient compounds in anticancer activity studies. Thus, a series of eleven 1,2-naphthoquinones tethered in C2 to 1,2,3-1H-triazoles 9a-k were designed, synthesized and their cyto
An. Acad. Bras. Ciênc.. Publicado em: 15/02/2018
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5. Suzuki-Miyaura Coupling between 3-Iodolawsone and Arylboronic Acids. Synthesis of Lapachol Analogues with Antineoplastic and Antileishmanial Activities
A series of 2-hydroxy-3-arylnaphthalene-1,4-diones (3-aryllawsones) were synthesized by Suzuki-Miyaura cross coupling reaction of 3-iodolawsone with arylboronic acids/esters. The hydroxylated resulting products were transformed into their corresponding N,N-diethyl carbamates. The antineoplastic and antileishmanial activities of the compounds were evaluated a
J. Braz. Chem. Soc.. Publicado em: 2017-08
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6. Farinha de casca de pequi em dietas para codornas japonesas
RESUMO. Este estudo foi realizado para avaliar os efeitos da farinha de casca de pequi (FCP) em dietas para codornas japonesas sobre o desempenho produtivo, a qualidade dos ovos e o custo dos ovos produzidos. Foram distribuídas 160 codornas (Coturnix coturnix japônica) em um delineamento inteiramente casualizado com quatro tratamentos e cinco repetições
Acta Sci., Anim. Sci.. Publicado em: 2016-03
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7. Synthesis of 1H-benzoxazine-2,4-diones from heterocyclic anhydrides: evaluation of antioxidant and antimicrobial activities
A facile one-step synthesis of 1H-benzoxazine-2,4-diones from heterocyclic anhydrides and TMSA was described. This paper determines their antimicrobial activity against nine human bacterial pathogens by the broth microdilution method; antioxidant activity by DPPH• inactivation and a ferric-reducing power assay; and toxicity by a brine shrimp, Artemia salin
Quím. Nova. Publicado em: 2014
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8. Egg parasitoids of Edessa meditabunda (Fabricius) (Pentatomidae) in lettuce crop
Egg parasitoids of Edessa meditabunda (Fabricius) (Pentatomidae) in lettuce crop. This study evaluated the occurrence of parasitoids in eggs of the stink bug, Edessa meditabunda (Fabricius, 1794) (Heteroptera, Pentatomidae) found on lettuce crop in Mato Grosso State, Brazil. Samples were collected in the vegetable garden "Cheiro Verde", in the municipality o
Rev. Bras. entomol.. Publicado em: 18/06/2013
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9. A multivariate statistical analysis of the QSAR of 2-(substituted phenyl)indan-1,3-diones with hypolipidemic activity
Descritores eletrônicos obtidos de cálculos de orbitais moleculares AM1, juntamente com os parâmetros log P e π, foram empregados para obter relações quantitativas estrutura-atividade (QSAR) para um conjunto de dezesseis derivados de 2-fenil-indan-1,3-dionas possuindo atividade hipolipidêmica. Os descritores AM1 foram obtidos tanto para o modelo da mo
J. Braz. Chem. Soc.. Publicado em: 02/10/2012
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10. Effect of feed restriction on performance of growing rabbits
This experiment assessed the effect of feed restriction in rabbits on performance and economic viability of the activity. Sixty New Zealand White rabbits, weaned at 33 days and slaughtered at 81 days of age, were used. The design was of randomized blocks with four treatments and five replications. The treatments were, as follows: 1 - free feeding, 2 - feed r
Revista Brasileira de Zootecnia. Publicado em: 2012-06
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11. Síntese, caracterização e estudo das propriedades fotoluminescente de complexos de európio com ligantes 2-Acilindan-1,3-Dionatos e Heteroaromáticos
O presente trabalho retrata a síntese, caracterização e o estudo das propriedades fotoluminescentes de complexos de európio(III) com ligantes tris-(2-acilindan-1,3-dionatos) (ACIND = 2-acetilindan-1,3-diona; BIND = 2-benzoilindan-1,3-diona; e PROPIND = 2-propionoilindan-1,3-diona) e heteroaromáticos auxiliares N coordenantes (bipy = 2,2‟-bipiridin
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/12/2011
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12. CaracterizaÃÃo tecnolÃgica e radiomÃtrica de um diabÃsio da regiÃo de ApuiarÃs - CE / Technological characterization and radiometric a region of diabase ApuiarÃs - CE
This paper presents the technological and mineralogical characteristics of a diabase, which outcrop in the form of dike is located in the district CanafÃstula in ApuiarÃs - CE. In order to assess their qualities for application as ornamental, were carried out technological tests of fitness levels and physical-mechanical, based on standards from ABNT, as we
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/01/2011