2 Xanthones
Mostrando 1-12 de 16 artigos, teses e dissertações.
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1. Mangostanaxanthone VIIII, a new xanthone from Garcinia mangostana pericarps, α-amylase inhibitory activity, and molecular docking studies
ABSTRACT A new xanthone: mangostanaxanthone VIIII [1,3,5,6,7-pentahydroxy-2-(3-methylbut-2-enyl)-8-(3-hydroxy-3-methylbut-1-enyl) xanthone] (5) and four known xanthones: mangostanaxanthones I (1) and II (2), γ-mangostin (3), and mangostanaxanthone VII (4) were separated and characterized from the acetone fraction of Garcinia mangostana L., Clusiaceae (mango
Rev. bras. farmacogn.. Publicado em: 27/05/2019
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2. Evaluation of cytogenotoxicity, antioxidant and hypoglycemiant activities of isolate compounds from Mansoa hirsuta D.C. (Bignoniaceae)
ABSTRACT Mansoa hirsuta (Bignoniaceae) is a native plant from caatinga in Brazilian semiarid. This plant has been locally used as antimicrobial and hypoglycemiant agents, but their action mechanisms and toxicity remain largely unknown. Therefore, we evaluated the composition and antioxidant, cytoprotective and hypoglycemiant effects of raw extract, fractions
An. Acad. Bras. Ciênc.. Publicado em: 2017-03
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3. Metabolic profile and β-glucuronidase inhibitory property of three species of Swertia
ABSTRACT β-Glucuronidase inhibitors are suggested as potential hepatoprotective agents. Swertia chirayita (Roxb.) Buch.-Ham. ex C.B. Clarke, Gentianaceae, is known for its hepatoprotective and anti-hepatotoxic activity in Ayurvedic system of medicine for ages. This plant is substituted by other species like S. decussata Nimmo ex C.B. Clarke and S. bimaculat
Rev. bras. farmacogn.. Publicado em: 2017-02
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4. Chemical constituents and leishmanicidal activity from leaves of Kielmeyera variabilis
Many phenolic compounds such as xanthones, quinones and coumarins have been isolated from Kielmeyera species; however the presence of flavonoids have been showed in other genera in the Calophylleae tribe as Caraipa, Mesua and Calophyllum. Six known glycosidic flavonoids: quercetin 3-β-O-galactopyranoside (1), quercetin 3-β-O-glucopyranoside (2), quercetin
Rev. bras. farmacogn.. Publicado em: 16/08/2012
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5. Antitumorigenicity of xanthones-rich extract from Garcinia mangostana fruit rinds on HCT 116 human colorectal carcinoma cells
This study aimed to investigate the antitumorigenicity of xanthones-rich extract from Garcinia mangostana L., Clusiaceae, fruit rinds which was obtained by a simple recrystallization of 75% ethanolic extract. α-Mangostin content of the extract was determined qualitatively by TLC and quantitatively by HPLC, and total xanthones content was quantified by UV sp
Revista Brasileira de Farmacognosia. Publicado em: 09/09/2011
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6. CONTRIBUTION TO THE PHARMACOGNOSTIC STUDY OF Polygala cyparissias Saint-Hilaire &Moquin (POLYGALACEAE): CHEMICAL ASPECTS AND EVALUATION OF THE GASTROPROTECTIVE AND ANTI-HYPERNOCICEPTIVE POTENTIAL / CONTRIBUIÇÃO AO ESTUDO FARMACOGNÓSTICO DE Polygala cyparissias Saint-Hilaire &Moquin (POLYGALACEAE): ASPECTOS QUÍMICOS E AVALIAÇÃO DE SEU POTENCIAL GASTROPROTETOR E ANTI-HIPERNOCICEPTIVO
Polygala cyparissias é uma planta popularmente conhecida como pinheiro da praia ou gelol. É etnofarmacologicamente utilizada como analgésico local de aplicação tópica, já tendo sido evidenciada a atividade antinociceptiva da planta. Caracterizase quimicamente pela presença de xantonas. Considerando que tais metabólitos já possuem atividade anti-úl
Publicado em: 2011
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7. Estudo fitoquÃmico de Vismia brasiliensis Choisy (Clusiaceae). / Phytochemical studies of Vismia brasiliensis Choisy (Clusiaceae).
Apesar de diversas plantas do gÃnero Vismia serem conhecidas por suas atividades contra diferentes tipos de fitopatÃgenos, ainda nÃo havia qualquer relato na literatura sobre as propriedades biolÃgicas Vismia brasiliensis Choisy. ConseqÃentemente, foram realizados testes biolÃgicos com o extrato metanÃlico das folhas de tal espÃcie vegetal com o obje
Publicado em: 2009
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8. Pre-clinical study of gastroprotective effect of mangiferin, a glucosylxanthone from Mangifera indica L., in experimental models of acute gastric mucosal injury / Estudos prÃ-clÃnicos do efeito gastroprotetor da mangiferina, uma glicosilxantona isolada de Mangifera indica L., em modelos experimentais de lesÃo gÃstrica aguda
Mangiferin, a glucosylxanthone from the fruiting tree Mangifera indica Linn. (Anacardiaceae), was evaluated for the first time in acute models of gastric injury. Mangiferin (3, 10 and 30 mg/kg, p.o.) significantly attenuated (p<0,001) the gastric damage induced by ethanol (30, 35 and 63% of reduction), acidified ethanol (27, 44 and 78% of inhibition), indome
Publicado em: 2008
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9. Anti-carie and antiproliferative effect of 7-epiclusianone, isolated from Rheedia genus plant / Avaliação das atividades anticarie e antiproliferativa da 7-epiclusianona isolada da planta do genero Rheedia
Considering the great use of plants as medicinal substances in the popular medicine, it is critical to investigate their biological and chemical properties in order to not only help to enhance our understanding of the therapeutic potential of these natural products, but also how to make them more effective pharmacological agents. The enormous biodiversitiy o
Publicado em: 2008
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10. Coumarins and xanthones from the seeds of Mammea siamensis
Uma cumarina inédita, mammea E/BB ciclo D (1), juntamente com cinco compostos conhecidos, mammea E/BA ciclo D (2), suragina C (3), terapina B (4), 1,7-dihidroxixantona (5) e 1-hidróxi-5-metoxyxantona (6), foram isolados de sementes de Mammea siamensis. Suas estruturas foram caracterizadas usando dados de RMN 1D e 2D. Suragina C e terapina B mostraram ativi
Journal of the Brazilian Chemical Society. Publicado em: 2007
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11. Antibacterial xanthones from Kielmeyera variabilis mart. (Clusiaceae)
The bioassay-guided fractionation of stems from Kielmeyera variabilis, traditionally used in Brazilian folk medicine, yielded assiguxanthone-B (1), kielcorin (4), 2,5-dihydroxybenzoic acid (3), and a mixture of xanthones containing assiguxanthone-B (1) and 1,3,5,6-tetrahydroxy-2-prenylxanthone (2) (1:1 w/w). The xanthone mixture inhibited Staphylococcus aure
Memórias do Instituto Oswaldo Cruz. Publicado em: 2003-06
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12. Estudo fitoquímico e avaliação da atividade moluscicida da Kielmeyera variabilis Mart (Clusiaceae)
Methanol extract obtained from Kielmeyera variabilis stems showed significant molluscicidal activity against Biomphalaria glabrata. The phytochemical studies of the plants stem to the isolation of three xanthones (assiguxanthone-B, kielcorin and 1,3,5,6-tetrahtydroxy-2-prenylxanthone) and a organic acid (2,5-dihydroxy benzoic acid). The structures of these c
Química Nova. Publicado em: 2003-03