131 Iodine
Mostrando 13-24 de 55 artigos, teses e dissertações.
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13. Radioiodine plus recombinant human thyrotropin do not cause acute airway compression and are effective in reducing multinodular goiter
Recombinant human thyrotropin (rhTSH) reduces the activity of radioiodine required to treat multinodular goiter (MNG), but acute airway compression can be a life-threatening complication. In this prospective, randomized, double-blind, placebo-controlled study, we assessed the efficacy and safety (including airway compression) of different doses of rhTSH asso
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-03
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14. Aplicação de método Monte Carlo para cálculos de dose em folículos tiroideanos
The Monte Carlo method is an important tool to simulate radioactive particles interaction with biologic medium. The principal advantage of the method when compared with deterministic methods is the ability to simulate a complex geometry. Several computational codes use the Monte Carlo method to simulate the particles transport and they have the capacity to s
Publicado em: 2008
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15. Influencia do metimazol na distribuicao dos radionuclideos 131I E 99m Tc em ratos / Influence of methimazole in distribution of radionuclides131I E 99m Tc in laboratorial rats
Radionuclides, such as 99mTc and 131I, being administered as radiopharmaceuticals have been used in Nuclear Medicine to diagnose and treat many diseases in humans. Syntheticâs drugs as methymazole are used in treatment of hiperthyroidism so as to reduces hormones before the radioactive treatment. Interaction between medicines and radionuclides can modify ra
Publicado em: 2007
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16. Efeito do metimazol na eficácia do tratamento com iodo radioativo e nos níveis séricos do TRAb na doença de Graves
O hipertireoidismo da doença de Graves é a forma mais comum de hipertireoidismo em pacientes entre 20-50 anos. Três abordagens terapêuticas são atualmente utilizadas, drogas antitireoidiana, cirurgia e iodo radioativo (131I). O iodo radioativo tem sido cada vez mais aceito como primeira escolha terapêutica, porque é um tratamento seguro, definitivo e
Publicado em: 2007
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17. Radiolabeling and biodistribution of monoclonal antibody (MAb) anti-CD20 with iodine-131
Radioisótopos de iodo, principalmente iodo-131 foram muito utilizados em vários procedimentos de marcação de anticorpos monoclonais usando diferentes métodos tais como o de Cloramina-T(CT). Neste estudo, observamos a influência de tempo de incubação, massa de CT, relação anticorpo/actividade na pureza radioquímica no anticorpo anti-CD20 marcado co
Brazilian Archives of Biology and Technology. Publicado em: 2005-10
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18. Leucemia Mielóide Aguda t(8;21) após tratamento de hipertiroidismo com iodo radioativo: Leucemia secundária?
Acute leukemia following treatment with Iodine131 is a rare event. The possible carcinogenic effect of Iodine131 is still not clear and a large series of cases did not show an increased incidence of cancer. A case of AML t(8;21), three years after Iodine131 treatment for hyperthyroidism, is reported. Secondary AML with t(8;21) is described following exposure
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2002-04
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19. UtilizaÃÃo da sonda a cintilaÃÃo na captaÃÃo de 131I pela TireÃide / Use of gamma probe in 131I thyroid uptake studies
Evaluation of thyroid uptake by administration of radioactive iodine is a well-defined procedure to assess patient thyroid function. In general, nuclear medicine institutions use gamma cameras coupled to pinhole collimators to perform uptake studies. With the growing use of intraoperative gamma probes in the radioguided surgical techniques, several instituti
Publicado em: 2002
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20. Otimizacao da dose terapeutica com 131I para carcinoma diferenciado da tireoidee
I-131 thyroid cancer therapy is based on the strategy of concentrating radioactive iodine in the thyroid tissue, to completely eliminate thyroid tissue and functioning thyroid cancer metastases remaining after thyroidectomy. In Brazil, fixed activities of 131 I generally are given, sometimes either delivering insufficient activities to ablate all of the remn
Publicado em: 2002
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21. Action of soybean on the thryroid of rats: inluence of the iodine of the ration / Ação da soja sobre a tireóide de ratos: influência do iodo da ração
Defatted autoclaved soybean flour presented a water/acetone soluble fraction which is able to depress I-131uptake by rat thyroids tested in 24hs "in vivo" or in 3hs "in vitro" assays. When this fraction was given to rats in ration with either normal or deficient iodine content for periods from 7 to 84 days no significant action was detected. On the other han
Publicado em: 1985
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22. A method for I131 conversion ratio utilizing the plasma inorganic I131 fraction
A method for calculating I131 conversion ratios by utilizing the inorganic I131 counts in the plasma at 24 hours is presented. Its chief advantage over previously used methods is that in cases of low conversion ratio it eliminates the large error introduced by fluctuations in the background of the counting equipment. The principle of the method depends upon
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23. Effects of 3-nitro-l-tyrosine on thyroid function in the rat: an experimental model for the dehalogenase defect
The effects on thyroid function of an inhibitor of tyrosine dehalogenase, 3-nitro-L-tyrosine (MNT) have been investigated in rats. In preliminary studies, marked inhibition of iodotyrosine deiodination was demonstrated in rats drinking 8 mM MNT. A series of experiments was then performed in which rats received Remington low iodine diet and 8 mM MNT as drinki
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24. EARLY EFFECTS OF THYROTROPIN ON PROTEIN-BOUND IODINE131 AND PLASMA IODIDE131*