1 Antibodies
Mostrando 25-36 de 10994 artigos, teses e dissertações.
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25. Decreased serum levels of IL-27and IL-35 in patients with Graves disease
ABSTRACT Objectives Graves’ disease (GD) is an autoimmune disease causing the overproduction of the thyroid hormone from thyroid gland. This disease is mainly the result of the production of antibodies against TSH receptors. Cytokines play an important role in orchestrating the pathophysiology in autoimmune thyroid disease. The regulatory role of IL-12 o
Arch. Endocrinol. Metab.. Publicado em: 2020-10
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26. Neonatal infection and passive acquisition of serum total IgG and reactive with “Streptococcus” B, anti-LPS of “Klebsiella spp” and “Pseudomonas spp” antibodies in twins
RESUMO OBJETIVOS Descrever o título de anticorpos IgG total e específico anti-Streptococcus B, anti-lipopolissacarídeos(LPS) de Klebsiella e Pseudomonas no cordão umbilical em gêmeos e analisar a possível associação entre os títulos desses anticorpos e a ocorrência de infecção. MÉTODOS Estudo prospectivo transversal de uma coorte de recém-nas
Rev. Assoc. Med. Bras.. Publicado em: 2020-06
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27. Reactivity of sera from dogs living in a leishmaniasis-endemic area to the COOH-terminal region of cysteine proteinase B
ABSTRACT Cysteine proteinases are well-known virulence factors of Leishmania spp. with demonstrated actions in both experimental mouse infection and human infection. However, studies on these enzymes in canine leishmaniasis are scarce. Here, we show, for the first time, the reactivity of sera from dogs living in an endemic area to a recombinant protein from
Braz J Infect Dis. Publicado em: 2020-06
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28. COVID-19: a meta-analysis of diagnostic test accuracy of commercial assays registered in Brazil
ABSTRACT The accuracy of commercially available tests for COVID-19 in Brazil remains unclear. We aimed to perform a meta-analysis to describe the accuracy of available tests to detect COVID-19 in Brazil. We searched at the Brazilian Health Regulatory Agency (ANVISA) online platform to describe the pooled sensitivity (Se), specificity (Sp), diagnostic odds ra
Braz J Infect Dis. Publicado em: 2020-04
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29. Selective case finding versus universal screening for detecting hypothyroidism in the first trimester of pregnancy: a comparative evaluation of a group of pregnant women from Rio de Janeiro
ABSTRACT Objective Maternal hypothyroidism during pregnancy may lead to adverse outcomes. Recently published guidelines by the American Thyroid Association (ATA) do not advocate for universal screening but recommend a case-finding approach in high-risk pregnant women. The present study aims to evaluate the accuracy of this approach in identifying women wit
Arch. Endocrinol. Metab.. Publicado em: 2020-04
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30. Measles, rubella, mumps and Toxoplasma gondii antibodies in saliva of vaccinated students of schools and universities in São Paulo City, Brazil
ABSTRACT Introduction: Vaccines are well-established public health interventions with major impacton the prevalence of infectious diseases, but outbreaks are occurring frequently due to pri-mary and secondary failures, despite high coverage. Surveillance of efficacy and duration ofinduced immunity is a difficult task as it requires invasive blood sampling i
Braz J Infect Dis. Publicado em: 2020-02
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31. Seroprevalence of chikungunya virus infection in five hospitals within Anyigba, Kogi State of Nigeria
ABSTRACT Febrile illnesses in developing countries are often misdiagnosed as malaria or typhoid fever. Although arboviral infections have similar clinical symptoms, they are usually not screened because of limited resources and the fact that there are several viruses in this group. Chikungunya virus (CHIKV) has been isolated in parts of Nigeria, but there is
Braz J Infect Dis. Publicado em: 2020-02
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32. Engineered scPDL1-DM1 drug conjugate with improved in vitro analysis to target PD-L1 positive cancer cells and intracellular trafficking studies in cancer therapy
Abstract Antibody-drug conjugates (ADC), precisely deliver a cytotoxic agent to antigen-expressing tumor cells by using specific binding strategies of antibodies. The ADC has shown the ability of potent bio-therapeutics development but indefinite stoichiometric linkage and full-length antibody penetration compromised the field of its advancement. Single chai
Genet. Mol. Biol.. Publicado em: 17/01/2020
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33. Seroprevalence of arenavirus and hantavirus in indigenous populations from the Caribbean, Colombia
Abstract INTRODUCTION: In Colombia, there is insufficient epidemiological surveillance of zoonotic hemorrhagic viruses. METHODS: We performed a sero-epidemiological study in indigenous populations of Wayuü, Kankuamos, and Tuchin communities using Maciel hantavirus and Junin arenavirus antigens for IgG detection by ELISA. RESULTS IgG antibodies to hanta
Rev. Soc. Bras. Med. Trop.. Publicado em: 20/12/2019
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34. Performance evaluation of an indirect immunofluorescence kit for the serological diagnosis of dengue
RESUMO Objetivo: Avaliar o desempenho da imunofluorescência indireta no diagnóstico sorológico de dengue em uma população com alta prevalência de arboviroses. Métodos: Duzentas amostras de soro de pacientes com suspeita clínica de dengue foram testadas por ensaio imunoenzimático e imunofluorescência indireta mosaico BIOCHIP®. Foram calculados es
Einstein (São Paulo). Publicado em: 20/12/2019
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35. Epidemiological, clinical and immune factors that influence the persistence of antiphospholipid antibodies in leprosy
Abstract Introduction: Antiphospholipid antibodies (aPL) are described in individuals with leprosy without the clinical features of antiphospholipid antibody syndrome (APS), a condition involving thromboembolic phenomena. We have described the persistence of these antibodies for over 5 years in patients with leprosy after specific treatment. Objectives: To
Adv. rheumatol.. Publicado em: 09/12/2019
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36. Prevalence of anti-tissue transglutaminase antibodies in patients with irritable bowel syndrome in Duhok city
Resumo Introdução A síndrome do intestino irritável (SII) é um distúrbio gastrointestinal comum; a doença celíaca é uma enteropatia autoimune que pode imitar qualquer distúrbio gastrointestinal funcional. O objetivo deste estudo foi estimar a prevalência de anticorpos contra a doença celíaca (antitransglutaminase tecidual - tTG) em pacientes co
J. Coloproctol. (Rio J.). Publicado em: 05/12/2019