1 3 4 Thiadiazole
Mostrando 1-12 de 12 artigos, teses e dissertações.
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1. SYNTHESIS, ELECTRONIC AND SPECTRAL PROPERTIES OF NEW 1,3,4-THIADIAZOLE COMPOUNDS AND THE SPECTRAL ANALYSIS OF THEIR CONFORMERS USING DENSITY FUNCTIONAL THEORY
In this study, new 1,3,4-thiadiazole compounds were synthesised and characterised by FT-IR, 1H-NMR, UV-vis spectroscopy and elemental analysis, Furthermore, the relationship between the electronic and spectral data of the 16 conformers of each compound was investigated by theoretical calculations; the theoretical data were compared with the experimental resu
Quím. Nova. Publicado em: 2019-02
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2. Selective Adsorption of AuIII from Aqueous Solution Using 2,5-Dimercapto-1,3,4-thiadiazole Modified Persimmon Tannin
A one-pot synthesized persimmon tannin (PT)-based novel biosorbent modified with 2,5-dimercapto-1,3,4-thiadiazole (DMTD) was prepared for the selective adsorption of AuIII from aqueous mixtures. The synthesized biosorbent was designated as DMTD-PT and characterized using elemental analysis, zeta potential, Fourier transform infrared (FTIR) spectroscopy and X
J. Braz. Chem. Soc.. Publicado em: 2018-07
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3. 1,3,4-Thiadiazole and 1,2,4-triazole-3(4 H )-thione bearing salicylate moiety: synthesis and evaluation as anti- Candida albicans
Abstract Dramatically increased occurrence of both superficial and invasive fungal infections has been observed. Candida albicans appear to be the main etiological agent of invasive fungal infections. The anti-C. albicans activity of thiosemicarbazide, 1,3,4-Thiadiazole, and 1,2,4-triazole-3(4H)-thione compounds (compounds 3-23) were investigated. The MIC va
Braz. J. Pharm. Sci.. Publicado em: 20/04/2017
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4. Synthesis, urease inhibition, antioxidant and antibacterial studies of some 4-amino-5-aryl-3H-1,2,4-triazole-3-thiones and their 3,6-disubstituted 1,2,4-triazolo[3,4-b]1,3,4-thiadiazole derivatives
Uma nova série de 4-amino-5-aril-3H-1,2,4-triazol-3-tionas, tendo vários grupos metoxibenzila e metoxifenila, foi sintetizada através de refluxo de sais de hidrazina carboditioato de potássio em solução aquosa diluída de hidrato de hidrazina. Estes sais foram formados pela reação de hidrazinas ácidas e dissulfeto de carbono em solução de hidróxi
Journal of the Brazilian Chemical Society. Publicado em: 2012-05
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5. SÃntese e avaliaÃÃo de atividades Anti-Toxoplama gondii e antimicrobiana de Tiossemicarbazidas, 4-Tiazolidinonas e 1,3,4-TiadiazÃis obidos a partir do Ãster 5-Metil-1H-Imidazol-4-Carboxilato de Etila
Toxoplasmosis is an infection caused by Toxoplasma gondii, a protozoan parasite with very complex biology and wide distribution in several geographical areas of the globe. In 2005, our research group published a paper reporting an exceptional anti-T. gondii activity for thiosemicarbazones and arylhydrazono-4-thiazolidinones, with a nitro group in aryl moiety
Publicado em: 2007
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6. Preparation of a silica gel modified with 2-amino-1,3,4-thiadiazole for adsorption of metal ions and electroanalytical application
Uma silica gel, com área específica de 382 m² g-1 e diâmetro médio de poro de 60 Å, foi modificada quimicamente com 2-amino-1,3,4-tiadiazol, com o propósito de adsorção seletiva de íons de metais pesados e possível utilização como um eletrodo de pasta de carbono quimicamente modificado (CMCPE). São discutidas as seguintes propriedades desta sí
Journal of the Brazilian Chemical Society. Publicado em: 2006-06
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7. Direct evidence of redox mediation between a poly(aniline-co-N-propanesulfonic acid aniline) and 2,5-dimercapto-1,3,4-thiadiazole by UV-visible reflectance spectroscopy
Neste trabalho é apresentado um estudo espectroeletroquímico do comportamento redox de filmes finos de um derivado de polianilina sulfonada, poli(anilina-co-N- ácido propanosulfônico anilina), (PAPSAH) e uma mistura do mesmo derivado com 2,5-dimercapto-1,3,4-tiodiazol (DMcT) por reflectância e transmissão no UV- visível. O estudo mostra as mudanças d
Journal of the Brazilian Chemical Society. Publicado em: 2002-08
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8. THE EFFECT OF INTRAVENOUSLY ADMINISTERED 6063, THE CARBONIC ANHYDRASE INHIBITOR, 2-ACETYLAMINO-1,3,4-THIADIAZOLE-5-SULFONAMIDE, ON FLUID AND ELECTROLYTES IN NORMAL SUBJECTS AND PATIENTS WITH CONGESTIVE HEART FAILURE
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9. Activity of Megazol, a Trypanocidal Nitroimidazole, Is Associated with DNA Damage
DNA damage associated with the trypanocidal activity of megazol [2-amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazole] was shown in experiments in which DNA repair-deficient RAD51−/− Trypanosoma brucei mutants were found to be hypersensitive to the drug. Parasites resistant to megazol were selected and showed modest cross-resistance to other trypa
American Society for Microbiology.
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10. Structure-activity relationships of new antiviral compounds.
In preliminary experiments, the compound 2-amino-5-(2-sulfamoylphenyl)-1,3,4-thiadiazole (G413) was shown to possess high activity against DNA viruses (herpes simplex viruses 1 and 2 and adenovirus 17) and RNA viruses (poliovirus 1, echovirus 2, and coxsackievirus B4). Experiments on the replicative cycle of poliovirus 1 and production of infectious RNA viru
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11. Differential expression of chitinases in Vitis vinifera L. responding to systemic acquired resistance activators or fungal challenge.
The concept of systemic acquired resistance (SAR) enables a novel approach to crop protection, and particular pathogenesis-related proteins, i.e. an acidic chitinase, have been classified as markers of the SAR response. Basic class I (VCHIT1b) and a class III (VCH3) chitinase cDNAs were cloned from cultured Vitis vinifera L. cv Pinot Noir cells and used to p
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12. A Novel Selective Muscarinic Acetylcholine Receptor Subtype 1 Antagonist Reduces Seizures without Impairing Hippocampus-Dependent LearningS⃞
Previous studies suggest that selective antagonists of specific subtypes of muscarinic acetylcholine receptors (mAChRs) may provide a novel approach for the treatment of certain central nervous system (CNS) disorders, including epileptic disorders, Parkinson's disease, and dystonia. Unfortunately, previously reported antagonists are not highly selective
American Society for Pharmacology and Experimental Therapeutics.