Sickle Cell Anemia
Mostrando 13-24 de 285 artigos, teses e dissertações.
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13. Prevalence of hemoglobin abnormalities in an apparently healthy population in Benin
ABSTRACT Background: Sickle cell disease is the most common monogenic disorder in humans and is a major public health concern in sub-Saharan Africa. In Benin, the prevalence of sickle cell disease is estimated to be 4.8%. Our study aimed to describe the prevalence of hemoglobin abnormalities in an apparently healthy Benin population. Methods: One thousand
Hematol., Transfus. Cell Ther.. Publicado em: 2020-06
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14. Bacterial meningitis in patients with sickle cell anemia in Salvador, Bahia, Brazil: a report on ten cases
ABSTRACT Sickle cell anemia (SCA) is a common genetic blood disorder, affecting millions worldwide. According to current evidence, individuals with SCA have more than 300 times greater risk to develop bacterial meningitis (BM) than the general population. Herein we have described the characteristics of a series of BM cases in SCA patients in Salvador, Brazil
Hematol., Transfus. Cell Ther.. Publicado em: 2020-06
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15. Chronic transfusion therapy effectiveness as primary stroke prophylaxis in sickle cell disease patients
Abstract Introduction About 10% of sickle cell anemia patients will have ischemic stroke. Adams showed stroke incidence reduction in children receiving monthly erythrocyte transfusions by reducing transcranial Doppler (TCD) velocities. Since then, chronic transfusion is recommended as primary stroke prophylaxis. This study aims to assess the effectiveness o
Hematol., Transfus. Cell Ther.. Publicado em: 2020-03
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16. Higher values of triglycerides:HDL-cholesterol ratio hallmark disease severity in children and adolescents with sickle cell anemia
Dyslipidemia has been described in sickle cell anemia (SCA) but its association with increased disease severity is unknown. Here, we examined 55 children and adolescents with SCA as well as 41 healthy controls to test the association between the lipid profiles in peripheral blood and markers of hemolysis, inflammation, endothelial function, and SCA-related c
Braz J Med Biol Res. Publicado em: 14/10/2019
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17. Iron deficiency, still a rarity in children with sickle cell anemia in Ile-Ife, Nigeria
ABSTRACT In this study, children with sickle cell anemia were evaluated for iron deficiency. Serum ferritin and free erythrocyte protoporphyrin free erythrocyte protoporphyrin (FEP) levels, mean corpuscular volume mean corpuscular volume (MCV) and mean corpuscular hemoglobin mean corpuscular hemoglobin (MCH) were used in determining their iron status. The st
Hematol., Transfus. Cell Ther.. Publicado em: 10/10/2019
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18. Screening on prenatal infections in the South and Southwest macro-regions in the State of Bahia, Brazil: detected on paper filter
Resumo Objetivos: estimar a taxa de detecção de patologias da TPN em papel de filtro nas regiões Sul e Sudoeste do Estado da Bahia, bem como delinear o perfil epidemiológico dessas gestantes, calcular e estimar a taxa de adesão e abrangência de cobertura do Programa. Métodos: estudo descritivo, de agosto 2013 a agosto de 2015, de dados obtidos do La
Rev. Bras. Saude Mater. Infant.. Publicado em: 16/09/2019
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19. Cognitive profile of children with sickle cell anemia compared to healthy controls,
Resumo Objetivo: Avaliar os sistemas cognitivos de crianças e adolescentes com anemia falciforme provenientes de triagem neonatal e compará-las com controles sadios, ajustando-se os resultados para o nível socioeconômico. Método: A avaliação cognitiva foi feita com a escala de Wechsler WISC-III em 64 crianças e adolescentes com anemia falciforme e
J. Pediatr. (Rio J.). Publicado em: 12/09/2019
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20. Avaliação do coping da dor em crianças com Anemia Falciforme
Resumo O enfrentamento (coping) da dor desempenha um papel importante na adaptação à doença crônica e seus efeitos. Este estudo analisou o coping da Anemia Falciforme em 12 crianças com idade entre oito e dez anos, que frequentavam um Hospital Universitário de Vitória, Espírito Santo, pelo Instrumento Informatizado de Avaliação do Enfrentamento da
Estud. psicol. (Campinas). Publicado em: 21/01/2019
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21. Effect of hydroxyurea (HU) on gelatinization mechanism of type I collagen suspensions
ABSTRACT Mutant hemoglobins thermodynamic phase transitions (HbS, HbC, etc.) have been the causes of serious hemoglobinopathies that have been affecting mankind since the dawn of human race. HbS polymerization is the best known of these transitions and the original cause of sickle cell anemia. Hydroxyurea (HU, NH2CONHOH) is widely used as the main drug admin
Matéria (Rio J.). Publicado em: 06/12/2018
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22. Review of a three-year study on the dental care of onco-hematological pediatric patients
The aim of this study was to provide an updated review of dental procedures undertaken at the dental unit of the Onco-hematology service of the Instituto da Criança at the Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (ICr/HC-FMUSP). We retrospectively reviewed 565 of 1902 medical and dental records of patients diagnosed with onc
Clinics. Publicado em: 03/12/2018
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23. Prevalence of anemia in schools of the metropolitan region of Curitiba, Brazil
ABSTRACT Background: Anemia during childhood is one of the biggest public health problems worldwide, including Brazil. Insufficient or abnormal production of hemoglobin, loss of iron and excessive destruction of red blood cells are the most common causes of anemia. Among the reasons of anemia, iron deficiency accounts for 50% of anemia cases in developing c
Hematol., Transfus. Cell Ther.. Publicado em: 2018-06
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24. Aortic Valve Replacement Combined with Ascending Aortic Aneurysmectomy in a Patient with Sickle Cell Disease: a Case Report
Abstract Sickle cell anemia is a haematological disorder characterized by multiple vaso-occlusive complications, resulting in a reduced life expectancy. These patients are exposed to several triggering factors for sickle cell crises when they are submitted to cardiovascular surgeries with extracorporeal circulation. Therefore, meticulous care and perioperati
Braz. J. Cardiovasc. Surg.. Publicado em: 2018-04