Rat
Mostrando 1-12 de 18688 artigos, teses e dissertações.
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1. Is the Wistar Rat a more Suitable Normotensive Control for SHR to Test Blood Pressure and Cardiac Structure and Function?
Abstract Background: There are divergences in the literature regarding the experimental model (Wistar-WIS or Wistar Kyoto-WKY) to be used as a Spontaneously Hypertensive Rat (SHR) control. The characterization of these models in terms of cardiovascular parameters provides researchers with important tools at the time of selection and application in scientifi
International Journal of Cardiovascular Sciences. Publicado em: 2022
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2. Impressions of the chronic 900-MHz electromagnetic field in the prenatal period on Purkinje cells in male rat pup cerebella: is it worth mentioning?
SUMMARY OBJECTIVE: The aim of this study was to examine the changes on the Purkinje cells in the cerebella of male rat pups born to pregnant dams that were exposed to an electromagnetic field in the prenatal period. METHODS: The first stage of the study involved 12 Sprague-Dawley rats, 6 male and 6 female, weighing between 180 and 250 g. The female rats in
Revista da Associação Médica Brasileira. Publicado em: 2022
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3. Occurrence of the mite Acanthonyssus proechimys (Mesostigmata: Macronyssidae) on a spiny rat in Brazil
RESUMO Os ácaros macronissídeos são ectoparasitas de vertebrados terrestres. Nós montamos e reexaminamos material de ácaros coletado em uma expedição entre 1987-1989 à Estação Ecológica de Maracá, Estado de Roraima, Brasil. Os espécimes foram identificados como Acanthonyssus proechimys Yunker e Saunders (Mesostigmata: Macronyssidae), que haviam
Acta Amazonica. Publicado em: 2022
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4. Molecular mechanism of benign biliary stricture inhibition by rosiglitazone-activated peroxisome proliferator-activated receptor gamma
SUMMARY OBJECTIVE: The aim of this study was to investigate whether rosiglitazone-activated peroxisome proliferator-activated receptor gamma can inhibit the occurrence of benign biliary stricture and further elucidate the relevant molecular signaling mechanism. METHODS: The primary cultured rat biliary fibroblasts following experiments were performed using
Revista da Associação Médica Brasileira. Publicado em: 2022
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5. The Induction of Hypothyroidism during Gestation Decreases Outer Hair Cell Motility in Rat Offspring
Abstract Introduction Perinatal hypothyroidism has a negative repercussion on the development and maturation of auditory system function. However, its long-term effect on auditory function remains unsettled. Objective To evaluate the effect of prenatal hypothyroidism on the auditory function of adult offspring in rats. Methods Pregnant Wistar rats were gi
International Archives of Otorhinolaryngology. Publicado em: 2022
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6. Antitumor activity of irinotecan with ellagic acid in C6 glioma cells
SUMMARY OBJECTIVE: Irinotecan-based combination chemotherapies in malignant gliomas need to be examined. The aim of this study was to investigate the synergetic effect of ellagic acid, a natural polyphenolic antioxidant compound, with irinotecan, an inhibitor of topoisomerase I enzyme, on the growth, cadherin switch, and angiogenic processes of a glioma cel
Revista da Associação Médica Brasileira. Publicado em: 2022
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7. Bioflavonoid exerts analgesic and antiinflammatory effects via transient receptor potential 1 channel in a rat model
Resumo Antecedentes A dor é uma sensação desconfortável no corpo. Kaempferol é um flavonoide com efeitos antinociceptivos. Canais receptores de potencial transitório têm sido caracterizados no sistema sensorial. Objetivo Este estudo avaliou o efeito antinociceptivo central do kaempferol e os possíveis mecanismos de ação do TRPV1. Métodos Capsai
Arquivos de Neuro-Psiquiatria. Publicado em: 2022
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8. Antioxidant Effect of Curcumin on the Prevention of Oxidative Damage to the Cochlea in an Ototoxic Rat Model Based on Malondialdehyde Expression
Abstract Introduction Aminoglycoside, as an antimicrobial medication, also has side-effects on the inner ears, bringing about hearing disorders. Curcumin has been proven to be a strong scavenger against various reactive oxygen species (ROS), and the increase in ROS production is considered to play an important role in the process of hearing disorder. Objec
International Archives of Otorhinolaryngology. Publicado em: 2022
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9. Cardioprotective Effect of Cilostazol on Ischemia-Reperfusion Injury Model
Abstract Introduction: To clarify the potential protective role of cilostazol on rat myocardial cells with ischemia-reperfusion injury (IRI) models. Methods: The study was conducted with three groups of 10 Wistar rats (control group, rats without any coronary ischemia; sham group, rats with coronary ischemia but without cilostazol administration; and cilos
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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10. Indoleamine-2,3-dioxygenase-related anti-inflammatory effects of 3-aminobenzamide and infliximab in experimental colitis
SUMMARY OBJECTIVE: This study aimed to investigate the presence of indoleamine-2,3-dioxygenase and bacterial translocation after the administration of 3-aminobenzamide and infliximab in the TNBS model of rat colitis. METHODS: The study group was divided into five categories as follows: group 1: (control), group 2: colitis+saline, group 3: colitis+3-aminobe
Revista da Associação Médica Brasileira. Publicado em: 2022
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11. Radioprotective Effect of Nigella Sativa Oil on Heart Tissues of Rats Exposed to Irradition
Abstract Background Various studies are ongoing related to the radioprotective agents. Herbal preparations are currently becoming popular because of their beneficial effects with fewer side effects compared to the synthetic/semi-synthetic medicines, and Nigella sativa oil (NSO) is only one of them. Objective To investigate NSO for its antioxidant effects
International Journal of Cardiovascular Sciences. Publicado em: 2022
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12. Effects of nigella sativa oil on allergic rhinitis: an experimental animal study
Abstract Objectives: Nigella sativa oil is known antiallergic and immunomodulatory effects. We aimed to compare this oil with mometasone furoate, a topical steroid, on a rat model in the prevention of allergic rhinitis symptoms. Methods: A total of 28 two-to-four-month-old Wistar Hannover rats weighing 250–350 g were randomly divided into four groups of
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022