Pharmacology
Mostrando 13-24 de 516 artigos, teses e dissertações.
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13. Toona sinensis: a comprehensive review on its traditional usages, phytochemisty, pharmacology and toxicology
Abstract Toona sinensis (Juss.) M.Roem, Meliaceae, a deciduous plant native to eastern and southeastern Asia, is widely used in Traditional Chinese Medicine. This paper was aimed to summarize the current advances in traditional usage, phytochemistry, pharmacology and toxicology of T. sinensis. In this review, various types of data of T. sinensis are discusse
Rev. bras. farmacogn.. Publicado em: 2019-02
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14. Analysis of the asynchronous dental teleconsulting of Telehealth Brazil Networks in Minas Gerais
Abstract: This cross-sectional study aimed to evaluate the asynchronous dental teleconsulting of Telehealth Brazil Networks Program in Minas Gerais. Data were collected from secondary databases of the Clinical Hospital of the Universidade Federal de Minas Gerais (CH/UFMG) and Medical School of UFMG (MS/UFMG), from July 2015 to July 2017. The variables analyz
Braz. oral res.. Publicado em: 17/12/2018
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15. Phage therapy: progress in pharmacokinetics
ABSTRACT The concept of phage therapy exists in the history and it has been ignored for a long time, but the consequence of drug resistance in pathogen bacteria has forced the forgotten kingdom of phage therapy to be re-explored. However, for the successful implementation and acceptance of phage therapy worldwide, the number of factors need to be addressed.
Braz. J. Pharm. Sci.. Publicado em: 14/05/2018
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16. Assessment of Metabolism of the Eastern Oyster and Eastern Elliptio Using NMR Spectroscopy
Metabolites are known to characterize the functional responses of a cell. Therefore, a quantitative measurement of metabolite profiles can provide insight into the underlying effect of genetic or environmental actions on cell metabolism. It follows then that the study of the metabolite profiles of bivalve mollusks, such as oysters, can be particularly worthw
J. Braz. Chem. Soc.. Publicado em: 2017-07
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17. The importance of animal studies in Exercise Science
Abstract The validity and relevance of research with animals for the development of knowledge in Exercise Science have for long been discussed. Given the complexity of the biological systems, the use of animal models offers a significant contribution to uncover new findings about acute and chronic effects of exercise, particularly when these studies in human
Motriz: rev. educ. fis.. Publicado em: 02/05/2017
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18. Natural Compounds from Mexican Medicinal Plants as Potential Drug Leads for Anti-Tuberculosis Drugs
ABSTRACT In Mexican Traditional Medicine 187 plant species are used in the treatment of respiratory conditions that may be associated with tuberculosis. In this contribution, we review the ethnobotany, chemistry and pharmacology of 63 species whose extracts have been assayed for antimycobacterial activity in vitro. Among these, the most potent is Aristolochi
An. Acad. Bras. Ciênc.. Publicado em: 09/02/2017
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19. Non-clinical studies in the process of new drug development - Part II: Good laboratory practice, metabolism, pharmacokinetics, safety and dose translation to clinical studies
The process of drug development involves non-clinical and clinical studies. Non-clinical studies are conducted using different protocols including animal studies, which mostly follow the Good Laboratory Practice (GLP) regulations. During the early pre-clinical development process, also known as Go/No-Go decision, a drug candidate needs to pass through severa
Braz J Med Biol Res. Publicado em: 12/12/2016
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20. Review on research of the phytochemistry and pharmacological activities of Celosia argentea
ABSTRACT Celosia argentea L., Amaranthaceae, is widely used as traditional medicine with a long history in China. It is a unique source of Semen Celosiae whose contributions include purging the hepatic pathogenic fire, improving eyesight, and treating other eye diseases. Over 79 compounds from this plant were isolated and identified, mainly including saponin
Rev. bras. farmacogn.. Publicado em: 2016-12
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21. ADME studies and preliminary safety pharmacology of LDT5, a lead compound for the treatment of benign prostatic hyperplasia
This study aimed to estimate the absorption, distribution, metabolism and excretion (ADME) properties and safety of LDT5, a lead compound for oral treatment of benign prostatic hyperplasia that has previously been characterized as a multi-target antagonist of α1A-, α1D-adrenoceptors and 5-HT1A receptors. The preclinical characterization of this compound co
Braz J Med Biol Res. Publicado em: 24/11/2016
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22. Scientific Performance of Brazilian Researchers in Pharmacology with grants from CNPq: A comparative study within the Brazilian categories
RESUMO No Brasil, o desempenho científico dos pesquisadores é um dos critérios importantes para a tomada de decisões na concessão de bolsas. Neste contexto, este trabalho teve como objetivo avaliar e comparar o perfil de 82 pesquisadores sêniors (nível 1A-D), os quais recebem bolsa de produtividade CNPq (Conselho Nacional de Desenvolvimento Científic
An. Acad. Bras. Ciênc.. Publicado em: 15/08/2016
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23. Several aspects of Zingiber zerumbet: a review
Abstract Zingiber zerumbet (L.) Roscoe ex Sm., Zingiberaceae, is a perennial, aromatic and tuberose plant that grows in humid locations. Also known as bitter ginger, Z. zerumbet is traditionally found throughout Asia, where it is widely used in foods, beverages and for ornamental purposes. The viscous juice present in the inflorescence of the plant is rich i
Rev. bras. farmacogn.. Publicado em: 2016-06
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24. Casinga-cheirosa organic extract impairment over Balb-c male mice behavioral phenotype
ABSTRACT Laetia suaveolens (Poepp.) Benth., Salicaceae, popularly known as "casinga-cheirosa", "caferana", or "laranjinha", is native to Brazil but not endemic to this country. A crude organic extract was obtained from the leaves and stem and intraperitoneally administered in male Balb-c mice. Its behavioral effects were evaluated in the open field and eleva
Rev. bras. farmacogn.. Publicado em: 2016-04