Monoamines
Mostrando 1-12 de 45 artigos, teses e dissertações.
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1. Uliginosin B, a natural phloroglucinol derivative with antidepressant-like activity, increases Na+,K+-ATPase activity in mice cerebral cortex
ABSTRACT Uliginosin B, a phloroglucinol isolated from Hypericum polyanthemum Klotzsch ex Reichardt, Hypericaceae, has antidepressant-like effect in the forced swimming test in rodents and inhibits monoamines neuronal reuptake without binding to their neuronal carriers. Studies showed the involvement of Na+,K+-ATPase brain activity in depressive disorders, as
Rev. bras. farmacogn.. Publicado em: 2016-10
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2. G-protein activation revealed by [35S]-GTPγS binding assay is involved on the antidepressant-like effect of Hyperi cum caprifoliatum and Hypericum polyanthemumcyclohexane extracts
AbstractPrevious studies by us demonstrated the antidepressant-like and antinociceptive effects of lipophilic extracts and dimeric acyl-phloroglucinols from species of the genus Hypericum native to Southern Brazil. Uliginosin B and HC1 (an enriched phloroglucinol fraction from Hypericum caprifoliatum) are able to inhibit monoamine synaptosomal uptake without
Rev. bras. farmacogn.. Publicado em: 2015-08
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3. Neurobiochemical mechanisms of a ketogenic diet in refractory epilepsy
A ketogenic diet is an important therapy used in the control of drug-refractory seizures. Many studies have shown that children and adolescents following ketogenic diets exhibit an over 50% reduction in seizure frequency, which is considered to be clinically relevant. These benefits are based on a diet containing high fat (approximately 90% fat) for 24 mon
Clinics. Publicado em: 2014-12
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4. Antidepressant-like effect of Hoodia gordonii in a forced swimming test in mice: evidence for involvement of the monoaminergic system
Hoodia gordonii is a plant species used traditionally in southern Africa to suppress appetite. Recently, it has been associated with a significant increase in blood pressure and pulse rate in women, suggesting sympathomimetic activity. The present study investigated the possible antidepressant-like effects of acute and repeated (15 days) administration of H
Braz J Med Biol Res. Publicado em: 07/11/2014
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5. DISTRIBUIÇÃO DA INERVAÇÃO DA RELAXINA -3 NO TECTUM E TEGMENTUM NO RATO SUGERE ENVOLVIMENTO DO NUCLEO INCERTUS EM REDES DEFENSIVAS CENTRAIS. / DISTRIBUTION INNERVATION OF RELAXIN -3 NO TECTUM E TEGMENTUM SUGGESTS THE RAT NUCLEO INCERTUS INVOLVEMENT IN CENTRAL NETWORKS DEFENSIVE.
Nos mamíferos, as divisões tectal e tegmental do tronco cerebral estão envolvidas em mecanismos de atenção e de respostas a estímulos ameaçadores, como os predadores. Esses centros são regulados por conexões ascendentes, mas os detalhes anatômicos e neuroquímicos desta unidade não são totalmente conhecidos. O núcleo incertus (NI) no tegmento po
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/08/2012
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6. Monoamines in the pedal plexus of the land snail Megalobulimus oblongus (Gastropoda, Pulmonata)
In molluscs, the number of peripheral neurons far exceeds those found in the central nervous system. Although previous studies on the morphology of the peripheral nervous system exist, details of its organization remain unknown. Moreover, the foot of the terrestrial species has been studied less than that of the aquatic species. As this knowledge is essentia
Publicado em: 2010
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7. InvestigaÃÃo dos efeitos centrais e gastroprotetores do isopulegol em camundongos / Evaluation of the central nervous system and gastroprotective effects of isopulegol in mice.
Isopulegol is a monoterpene alcohol present in the essential oils of various plants, and has been used in the manufacture of fragrances with blossom compositions. In order to investigate its effects on animal models of CNS actions, isopulegol was administered to male Swiss mice at single doses of 25 and 50 mg/kg 30 (i.p.) or 60 min (p.o.) before the experime
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/08/2009
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8. Estudo dos efeitos comportamentais e neuroquÃmicos do extrato padronizado de Justicia pectoralis (chambÃ) em camundongos / Behavioral and neurochemical study of standardized extract of justicia pectoralis (CHAMBÃ) in mice.
O extrato padronizado de chambÃ, preparado a partir das partes aÃreas da Justicia pectoralis Jacq. var stenophylla Leonard, foi avaliado em modelos animais clÃssicos para screening de drogas com atividade em ansiedade, depressÃo, sedaÃÃo e convulsÃo, tais como, labirinto em cruz elevado (LCE), claro/escuro, campo aberto, rota rod, nado forÃado, suspe
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/07/2009
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9. AlteraÃÃes comportamentais e neuroquÃmicas provocadas por diferentes perÃodos de retirada apÃs tratamento subcrÃnico com cocaÃna em ratos: envolvimento dos sistemas dopaminÃrgico, serotonÃrgico e noradrenÃrgico / Behavioral and neurochemistry alterations caused by different times of withdrawal after subcronic treatment with cocaine in rats: Involvement of dopaminergic system, serotonergic and noradrenergic
A cocaÃna à uma droga consumida mundialmente e considerada hoje como um problema de saÃde pÃblica. Uma das principais dificuldades enfrentadas no combate ao vÃcio da cocaÃna, na maioria dos casos, està relacionada aos sintomas de abstinÃncia da droga, como ansiedade, depressÃo, irritabilidade, fadiga e insÃnia, fazendo com que o indivÃduo volte a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/07/2009
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10. ROLE OF DOPAMINE UPTAKE AND THEIR METABOLITES IN THE OROFACIAL DYSKINESIA INDUCED BY NEUROLEPTICS IN RATS / PAPEL DA RECAPTAÇÃO E DE METABÓLITOS DA DOPAMINA NA DISCINESIA OROFACIAL INDUZIDA POR NEUROLÉPTICOS EM RATOS
Fluphenazine-induced orofacial dyskinesia (OD) is a putative animal model of tardive dyskinesia (TD) whose pathophysiology has been related to an increase in dopamine hypersensitivity and oxidative stress. Data from literature have shown that patients with TD present a decrease in dopamine transporter (DAT) expression. In a previously study, we have demonstr
Publicado em: 2008
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11. Changes in the biogenic amine content of the prefrontal cortex, amygdala, dorsal hippocampus, and nucleus accumbens of rats submitted to single and repeated sessions of the elevated plus-maze test
It has been demonstrated that exposure to a variety of stressful experiences enhances fearful reactions when behavior is tested in current animal models of anxiety. Until now, no study has examined the neurochemical changes during the test and retest sessions of rats submitted to the elevated plus maze (EPM). The present study uses a new approach (HPLC) by l
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-12
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12. Evaluation of the central effects of yangambin isolated from Ocotea duckei Vattimo: Behavioral and neurochemical study in mice motor cortex and striatum / Avaliação dos efeitos centrais da iangambina isolada de Ocotea duckei Vattimo: Estudo comportamental e neuroquímico em córtex motor e corpo estriado de camundongo
The effects of the acute administration of yangambin (25, 50 and 75 mg/kg intraperitoneal and oral), were studied in some animals behavioral models (open field, rotarod, forced swimming test, barbiturate-induced sleeping time, hole board, elevated plus maze, pentilenotetrazole-induced convulsion). Binding in vitro with differents concentrations of yangambin
Publicado em: 2005