Microarray
Mostrando 1-12 de 1736 artigos, teses e dissertações.
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1. Identification of genomic imbalances in oral clefts
Abstract Objective This article presents a clinical and cytogenomic approach that focuses on the diagnosis of syndromic oral clefts (OCs). Methods The inclusion criteria were individuals with OC presenting four or more minor signs and no major defects (non-syndromic oral clefts [NSOCs]) as well as individuals with OC presenting at least another major defec
J. Pediatr. (Rio J.). Publicado em: 2021-06
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2. Merging Pediatric Index of Mortality (a physiologic instability measure), lactate, and Systemic Inflammation Mortality Risk to better predict outcome in pediatric sepsis
Abstract Objective This article presents a clinical and cytogenomic approach that focuses on the diagnosis of syndromic oral clefts (OCs). Methods The inclusion criteria were individuals with OC presenting four or more minor signs and no major defects (non-syndromic oral clefts [NSOCs]) as well as individuals with OC presenting at least another major defec
J. Pediatr. (Rio J.). Publicado em: 2021-06
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3. NADPH Oxidase 5 upregulation is associated with lymphoma aggressiveness
RESUMO OBJETIVOS Os linfomas são um grupo heterogêneo de neoplasias malignas de células linfoides B e NK/T maduras e imaturas em vários estágios de diferenciação. Ferramentas de biologia molecular e genética são usadas para classificar adequadamente o tipo e o prognóstico dos linfomas, os quais têm implicações na eficácia terapêutica. Entre
Rev. Assoc. Med. Bras.. Publicado em: 2020-02
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4. Expression of stromal elements of prostatic adenocarcinoma in different gleason scores
Abstract Purpose: To quantify and compare the expression of stromal elements in prostate adenocarcinoma of different Gleason scores with non-tumor area (control). Methods: We obtained 132 specimens from samples of prostate peripheral and transition zone. We analyzed the following elements of the extracellular matrix: collagen fibers, elastic system, smooth
Acta Cir. Bras.. Publicado em: 13/12/2019
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5. Genome-wide identification and characterization of R2R3-MYB genes in Medicago truncatula
Abstract MYB is a large family of plant transcription factors. Its function has been identified in several plants, while there are few reports in Medicago truncatula. In this study, we used RNA-seq data to analyze and identify R2R3-MYB genes in the genome of Medicago truncatula. Phylogenetic analysis classified 150 MtMYB genes into 21 subfamilies with homolo
Genet. Mol. Biol.. Publicado em: 14/11/2019
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6. [PROVISIONAL] Overexpression of rice F-box protein OsFBX322 confers increased sensitivity to gamma irradiation in Arabidopsis
Abstract Ionizing radiation has a substantial effect on physiological and biochemical processes in plants via induction of transcriptional changes and diverse genetic alterations. Previous microarray analysis showed that rice OsFBX322, which encoded a rice F-box protein, was downregulated in response to three types of ionizing radiation: gamma irradiation, i
Genet. Mol. Biol.. Publicado em: 02/09/2019
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7. IMUNOMARCAÇÃO DE TGF-β EM PRÓSTATAS CANINAS NORMAIS E COM LESÕES PROLIFERATIVAS
Resumo O fator de crescimento transformador-β (TGF-β), um mediador do crescimento prostático, induz a angiogênese e inibe a proliferação celular. Neste estudo, esse marcador foi utilizado com o objetivo de avaliar sua imunomarcação no tecido normal e com lesões proliferativas benignas, pré-neoplásicas e neoplásicas da próstata canina. Para isso,
Ciênc. anim. bras.. Publicado em: 22/08/2019
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8. Alterations in the Transcriptional Profile of the Liver Tissue and the Therapeutic Effects of Propolis Extracts in Alcohol-induced Steatosis in Rats
Abstract Abstract: The hepatoprotective effects of the ethanolic extracts of propolis (EEP) on alcohol-induced liver steatosis were investigated in Wistar rats. Chronic alcoholic fatty liver was induced by administration of 52% alcohol to male Wistar rats at the dose of 1% body weight for 7 weeks. Then animals were simultaneously treated with 50% ethanol sol
An. Acad. Bras. Ciênc.. Publicado em: 12/08/2019
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9. Gene expression profiling reveals upregulated FUT1 and MYBPC1 in children with pancreaticobiliary maljunction
Pancreaticobiliary maljunction (PBM) is associated with high risk of epithelial atypical growth and malignant transformation of the bile duct or gallbladder. However, overall changes in genetic expression have not been examined in children with PBM. Genome-wide expression was analyzed using peripheral blood samples from 10 children with PBM and 15 pediatric
Braz J Med Biol Res. Publicado em: 29/07/2019
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10. Population genomics and gene introgression in goat herds naturally adapted to Brazil
RESUMO Objetivou-se aplicar Chip SNP caprinos 50 K da Illumina para analisar a estrutura genômica populacional em dois rebanhos de caprinos Marota, um particular e outro de conservação oficial, localizados no Piauí, e na investigação de indícios de erosão genética provocada pela raça Anglonubiana nesses rebanhos. Para isso, 86 animais Marota e 10 A
Rev. Ciênc. Agron.. Publicado em: 04/07/2019
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11. Immunoexpression of TS, p53, COX2, EGFR, MSH6 and MLH1 biomarkers and its correlation with degree of differentiation, tumor staging and prognostic factors in colorectal adenocarcinoma: a retrospective longitudinal study
ABSTRACT BACKGROUND: There are cases of colorectal tumors that, although small, show more aggressive evolution than large tumors. This motivated us to study whether there are any proteins capable of alerting about these changes. The aim here was to correlate the immunoexpression of the TS, p53, COX2, EGFR, MSH6 and MLH1 biomarkers in tumors in patients wit
Sao Paulo Med. J.. Publicado em: 08/05/2019
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12. Expression analysis of long non-coding RNAs in a renal ischemia-reperfusion injury model
Abstract Purpose: To investigate the long non-coding RNAs (lncRNAs) profile on renal ischemia reperfusion in a mouse model. Methods: Microarray analysis was used to study the expression of misregulated lncRNA in a mouse model of renal ischemia reperfusion(I/R) with long ischemia time. Quantitative real-time PCR (qPCR) was used to verify the expression of
Acta Cir. Bras.. Publicado em: 29/04/2019