Lipase
Mostrando 1-12 de 1354 artigos, teses e dissertações.
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1. Como manejar paciente com pancreatite crônica não alcoólica?
O objetivo do tratamento da pancreatite crônica concentra-se no alívio da dor e na correção da má-absorção.
Há 4 passos iniciais para o tratamento da pancreatite: suspender o uso de álcool, dieta hipolipídica, normalização dos triglicerídeos (triglicerídeos maior que 500mg/dL necessitam início imediato de medicação), e suspender dro
. Publicado em: 12/06/2023
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2. A fitoterapia pode ser uma opção terapêutica para obesidade?
O tratamento da obesidade é complexo e multidisciplinar, sendo que pode incluir intervenções não medicamentosas e medicamentosas. A fitoterapia, entre outros, é um tratamento não medicamentoso que pode estar associado a outros tratamentos da obesidade.¹ Há estudos que avaliam algumas plantas medicinais para o tratamento da obesidade, dentre as q
Núcleo de Telessaúde Santa Catarina. Publicado em: 12/06/2023
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3. A Colorimetric and Fluorescent Dual-Signal Sensor for Detecting Lipase Activity Based on Inner Filter Effect
We developed a colorimetric and fluorescence dual-signal sensor for detecting lipase activity based on methyl thioglycolate (MT) functionalized gold nanoparticles (MT-AuNPs) and CdS quantum dots (CdS QDs). It is the first time that was developed a dual-signal sensing strategy for lipase activity based on the inner-filter effect (IFE) between MT-AuNPs and CdS
Journal of the Brazilian Chemical Society. Publicado em: 2022
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4. PLANEJAMENTO FATORIAL NA SÍNTESE DO OLEATO DE ETILA CATALISADA PELA LIPASE NATIVA DE Aspergillus niger
This work reports the use of the Octave, a free computational software, to optimize the experimental design in the synthesis of ethyl oleate from oleic acid and ethanol catalyzed by a native lipase from Aspergillus niger. The central composite factorial design (CCD) was performed with 2 levels and 3 variables (temperature, mass of native A. niger lipase and
Química Nova. Publicado em: 2022
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5. Lysosomal acid lipase deficiency in pediatric patients: a scoping review
Abstract Objective: Lysosomal acid lipase deficiency (LAL-D) is an underdiagnosed autosomal recessive disease with onset between the first years of life and adulthood. Early diagnosis is crucial for effective therapy and long-term survival. The objective of this article is to recognize warning signs among the clinical and laboratory characteristics of LAL-D
Jornal de Pediatria. Publicado em: 2022
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6. Supercritical Carbon Dioxide Effect on Lipase-Catalyzed Geranyl Acetate Synthesis
This work provides a general insight on lipase-catalyzed synthesis of geranyl acetate through esterification of geraniol with acetic acid. Although this reaction is relatively well known, the replacement of organic solvents by supercritical fluids is fairly recent and the role of CO2 is still not completely understood. Therefore, reactions were performed wit
Journal of the Brazilian Chemical Society. Publicado em: 2022
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7. Obesity-associated Pathways of Anthocyanins
Abstract Anthocyanins have a great potential for human health, as a sub-group of phenolic compounds. Interactions of anthocyanin involved in digestion and thus in obesity consist of inhibition of pancreatic lipase, regulation of lipolysis and lipogenesis, activation of an activated protein kinase enzyme, controlling of digestion hormones (leptin, insulin, gh
Food Sci. Technol. Publicado em: 2021-06
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8. Chemoenzymatic Synthesis of Apremilast: A Study Using Ketoreductases and Lipases
The key step in the chemoenzymatic synthesis of apremilast was to produce the chiral alcohol (R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanol, (R)-3. Two enzymatic approaches were evaluated to obtain (R)-3, one using ketoreductases and the other lipases. Bioreduction of 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone (2), using ketoreductas
J. Braz. Chem. Soc.. Publicado em: 2021-05
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9. HSCCC Separations of Rutin Esters Obtained by Enzymatic Reaction Catalyzed by Lipase
The flavonoid rutin presents several pharmacological effects, despite this, its application in the pharmaceutical industry can be significantly limited by its low bioavailability. The development of lipophilic derivatives by esterification of hydroxyl groups with fatty acid chains may be an effective strategy to change their physicochemical properties. This
J. Braz. Chem. Soc.. Publicado em: 2021-03
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10. Pseudomonas SP. in uninspected raw goat’s milk in Rio de Janeiro, Brazil
Abstract Although quite controversial from the point of view of food safety, a considerable number of people across different age and socioeconomic groups consume raw goat’s milk. Even if refrigerated after milking, raw goat's milk may still be susceptible to the lipolytic and proteolytic actions of psychrotrophic microorganisms, such as Pseudomonas. In th
Food Sci. Technol. Publicado em: 2020-12
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11. Corticosteroid associated lupus pancreatitis
RESUMO A relação entre pancreatite aguda e a administração de glicocorticoides é incerta pois a maioria dos casos relatados foram diagnosticados com doenças vasculares sistêmicas, como lúpus eritematoso sistêmico, que pode causar pancreatite. Uma paciente de 22 anos com envolvimento ocular e lúpus eritematoso sistêmico recém-diagnosticado foi adm
Rev. Assoc. Med. Bras.. Publicado em: 2020-10
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12. IMPROVING THE CATALYTIC FEATURES OF THE LIPASE FROM Rhizomucor miehei IMMOBILIZED ON CHITOSAN-BASED HYBRID MATRICES BY ALTERING THE CHEMICAL ACTIVATION CONDITIONS
The lipase from Rhizomucor miehei (RML) has been immobilized on chitosan-based hybrid (sodium alginate or carrageenan) matrices activated with glycidol (GLY), epichlorohydrin (EPI) or glutaraldehyde (GLU) groups. Then, the properties of the different biocatalysts have been evaluated and compared with the soluble RML. Thermal stability (at pH 7.0 and 60 °C)
Quím. Nova. Publicado em: 2020-09