Leishmania
Mostrando 1-12 de 2385 artigos, teses e dissertações.
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1. Quando suspeitar de leishmaniose visceral e/ou cutânea?
Diante de pessoas provenientes ou vivendo em regiões endêmicas de Leishmaniose, que se apresentem com febre persistente, astenia, adinamia, desnutrição, hepato e/ou esplenomegalia deve-se suspeitar de leishmaniose visceral (LV). Já diante de pessoas que apresentem úlcera indolor em áreas expostas da pele, com formato arredondado ou ovalado, base er
Núcleo de Telessaúde Sergipe. Publicado em: 12/06/2023
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2. Investigation of Chlamydia sp., Morbillivirus sp., Parvovirus sp., Leishmania sp. and Alphacoronavirus sp. in captive giant anteaters (Myrmecophaga tridactyla)
RESUMO Esta pesquisa teve como objetivo investigar a ocorrência de Chlamydia sp., Morbillivirus sp., Parvovirus sp., Leishmania sp. e Alphacoronavirus sp. em tamanduás-bandeira cativos. Foram colhidas amostras de sangue e fezes de 16 animais em instituições dos estados de Minas Gerais, Bahia e Distrito Federal, que estavam em cativeiro há pelo menos um
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2022
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3. Exuberant case of verrucous cutaneous leishmaniasis
Abstract Cutaneous leishmaniasis represents a public health problem that affects 85 countries. It is an endemic disease in Brazil, having an important socioeconomic impact. An exuberant case of cutaneous leishmaniasis is reported herein. A 28-year-old male patient with Down syndrome had had verrucous plaques on the back for over a year, with progressive grow
Anais Brasileiros de Dermatologia. Publicado em: 2022
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4. Axillary papules: an uncommon location of lichen nitidus
Abstract Cutaneous leishmaniasis is characterized by ulcers with raised edges and a granular bottom, mainly on the lower limbs. This is a case report of a male patient with an ulcer on the left plantar region. The diagnosis was confirmed by positive PCR for L. braziliensis and the presence of amastigotes of Leishmania sp. in the histopathological examination
An. Bras. Dermatol.. Publicado em: 2021-06
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5. Plantar ulcer as an atypical manifestation of cutaneous leishmaniasis
Abstract Cutaneous leishmaniasis is characterized by ulcers with raised edges and a granular bottom, mainly on the lower limbs. This is a case report of a male patient with an ulcer on the left plantar region. The diagnosis was confirmed by positive PCR for L. braziliensis and the presence of amastigotes of Leishmania sp. in the histopathological examination
An. Bras. Dermatol.. Publicado em: 2021-06
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6. Isolation and characterization of sesquiterpene lactones from Calea uniflora Less. and their leishmanicidal and trypanocidal activities
Calea uniflora Less., commonly known in Brazil as “erva-de-lagarto” and “arnica-da-praia”, is used in folk medicine to treat internal and external bruises and as anti-inflammatory. However, despite the popular use there is a lack of information in terms of isolation and biological evaluation of its secondary metabolites. Thus, the aims of this study
Quím. Nova. Publicado em: 2021-06
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7. Synthesis, in silico Study and Antileishmanial Evaluation of New Selenides Derived from 7-Chloro-quinoline and N-Phenylacetamides
This study describes a virtual screening performed for two series of selenides (28 compounds), derived from N-phenylacetamides chlorides and 7-chloro-quinoline, to determine their potential for leishmanicidal activity against Leishmania amazonensis and Leishmania donovani. Seven compounds were predicted as potential leishmanicides; therefore, they were synth
J. Braz. Chem. Soc.. Publicado em: 2021-04
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8. Antileishmanial Acetylene Fatty Acid and Acetogenins from Seeds of Porcelia macrocarpa
In the present work five acetylene derivatives (1-5), including three unknowns (1, 3 and 4), were isolated from seeds of Porcelia macrocarpa (Annonaceae). The structures of isolated compounds were determined as docos-13-yn-21-enoic acid (1), 3-hydroxy-4-methylene-2-(eicos-11’-yn-19’-enyl)but-2-enolide (2), 3-hydroxy-4-methylene-2-(octadec-9’-yn-17’-e
J. Braz. Chem. Soc.. Publicado em: 2021-02
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9. ANTIPROMASTIGOTE AND CYTOTOXIC ACTIVITIES OF FLAVONOIDS FROM Fridericia speciosa LEAVES
Fridericia speciosa (Bignoniaceae) is a liana that occurs in humid to dry vegetation in eastern and southeastern Brazil. Species belonging to the genus Fridericia are employed as medicinal plants. This study evaluates the antipromastigote and cytotoxic activities of the crude extract, fractions, and compounds isolated from F. speciosa, and an HPLC (High-Perf
Quím. Nova. Publicado em: 2020-12
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10. Dereplication of Aporphine Alkaloids by UHPLC-HR-ESI-MS/MS and NMR from Duguetia lanceolata St. -Hil (Annonaceae) and Antiparasitic Activity Evaluation
Although the genus Duguetia is well known for producing alkaloids as chemical constituents, there are no reports of alkaloids identified in the species D. lanceolata. Thus, aiming to identify the chemical composition of this species, the dereplication of alkaloidic phase was performed by use of ultra-high performance liquid chromatography high resolution ele
J. Braz. Chem. Soc.. Publicado em: 2020-09
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11. Identification of Leishmania species by high-resolution DNA dissociation in cases of American cutaneous leishmaniasis,
Abstract Background American cutaneous leishmaniasis is an infectious dermatosis caused by protozoa of the genus Leishmania, which comprises a broad spectrum of clinical manifestations depending on the parasite species involved in the infections and the immunogenetic response of the host. The use of techniques for amplification of the parasites DNA based on
An. Bras. Dermatol.. Publicado em: 2020-08
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12. Synthesis, Antileishmanial Activity and Spin Labeling EPR Studies of Novel β-Carboline-Oxazoline and β-Carboline-Dihydrooxazine Derivatives
A series of novel 1-(substituted-phenyl)-3-(4,5-dihydro-1,3-oxazol-2-yl)-9H-β-carboline (8a-8i) and 1-(substituted-phenyl)-3-(5,6-dihydro-4H-1,3-oxazin-2-yl)-9H-β-carboline (9a-9h) derivatives, as well as their respective N-(chloroalkyl)-1-(substituted-phenyl)-9H-β-carboline-3-carboxamide precursors (6a-6i and 7a-7h), were synthesized and evaluated for th
J. Braz. Chem. Soc.. Publicado em: 2020-06