Haplotypes
Mostrando 1-12 de 1026 artigos, teses e dissertações.
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1. HLA DQ2/DQ8 haplotypes and anti-transglutaminase antibodies as celiac disease markers in a pediatric population with type 1 diabetes mellitus
ABSTRACT Objectives: Evaluate the celiac disease (CD) markers, within the scope of its screening, in a pediatric population with diagnosis of type 1 diabetes (T1D) at Hospital de Braga (HB) and determine the prevalence of CD in the sample. Reflect on CD screening algorithm applied in this pediatric population. Subjects and methods: Retrospective observatio
Archives of Endocrinology and Metabolism. Publicado em: 2022
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2. Polymorphisms rs2010963 and rs833061 of the VEGF gene in polycystic ovary syndrome
SUMMARY OBJECTIVE: The polycystic ovary syndrome is the most common endocrine disorder, characterized by the dysregulation of ovarian angiogenesis. This alteration can be related to changes in the activities of the vascular endothelial growth factor (VEGF) gene. Single-nucleotide polymorphisms have been observed in the promoter, intronic, and untranslated r
Revista da Associação Médica Brasileira. Publicado em: 2022
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3. Genetic Diversity and Phyletic Evolution of Eleven Chinese Indigenous and Three Commercial Chicken Breeds by mtDNA Sequences
ABSTRACT Chinese indigenous chicken breeds are geographically widespread, and a total of 116 indigenous chicken breeds are listed as Chinese national genetic resources. However, these indigenous chicken breeds are facing serious challenges as declining population and germplasm degeneration because lots of commercial chicken breeds had been introduced. In thi
Braz. J. Poult. Sci.. Publicado em: 20/12/2019
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4. THE SINGLE NUCLEOTIDE POLYMORPHISMS OF MYOSTATIN GENE AND THEIR ASSOCIATIONS WITH GROWTH AND CARCASS TRAITS IN DAHENG BROILER
ABSTRACT Myostatin (MSTN) is a negative regulator of skeletal muscle growth. In order to investigate whether there is a correlation between MSTN polymorphisms and chicken production performance, in this study, single nucleotide polymorphisms (SNPs) in MSTN gene were examined across 180 Daheng broilers by direct sequencing of PCR product, and the correlations
Braz. J. Poult. Sci.. Publicado em: 05/12/2019
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5. Gene pool sharing and genetic bottleneck effects in subpopulations of Eschweilera ovata (Cambess.) Mart. ex Miers (Lecythidaceae) in the Atlantic Forest of southern Bahia, Brazil
Abstract Forest loss and fragmentation are the main threats to the maintenance of the Atlantic Forest, an important global biodiversity hotspot. Because of the current critical level of deforestation, ecological corridors are needed to facilitate species dispersion and gene flow among fragments. This study was conducted to investigate the genetic variability
Genet. Mol. Biol.. Publicado em: 14/11/2019
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6. Molecular survey of tick-borne pathogens in small mammals from Brazilian Amazonia
Resumo Pequenos mamíferos não voadores (marsupiais e pequenos roedores) foram capturados em três diferentes períodos, ao longo de 23 fragmentos florestais de três municípios (Alta Floresta, Sinop e Cláudia), localizados no bioma amazônico do Estado de Mato Grosso, no centro-oeste do Brasil. Os tecidos dos animais (fígado e baço) e sangue foram sele
Rev. Bras. Parasitol. Vet.. Publicado em: 07/11/2019
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7. Mancha areolada de Thanatephorus da seringueira na Amazônia: identificação filogenética e variação genética em populações do patógeno
RESUMO A mancha areolada de Thanatephorus é uma das doenças mais importantes da seringueira (Hevea brasiliensis) na Amazônia. Apesar disso, questão importante sobre o real posicionamento filogenético deste patógeno ainda não foi respondida. Neste estudo, nós analisamos os padrões de variação genética em seqüências da região ITS-5.8S do rDNA de
Summa phytopathol.. Publicado em: 14/10/2019
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8. Genetic diversity of Echinococcus vogeli in the western Brazilian Amazon
Human polycystic echinococcosis is a parasitic infection caused by the larval stage of Echinococcus vogeli, which occurs in rural areas of Central and South America. Until now, little information on the genetic variability of E. vogeli is available. Here, 32 samples from human-excised E. vogeli cysts had a 396-bp sequence of the mitochondrial cytochrome oxid
Mem. Inst. Oswaldo Cruz. Publicado em: 26/09/2019
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9. [PROVISIONAL] -866G/A and Ins/Del polymorphisms in the UCP2 gene and diabetic kidney disease: case-control study and meta-analysis
Abstract Uncoupling protein 2 (UCP2) decreases reactive oxygen species (ROS) formation by mitochondria. ROS overproduction is a key contributor to the pathogenesis of diabetic kidney disease (DKD). Thus, UCP2 polymorphisms are candidate risk factors for DKD; however, their associations with this complication are still inconclusive. Here, we describe a case-c
Genet. Mol. Biol.. Publicado em: 02/09/2019
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10. Does the widely distributed rodent Calomys tener (Cricetidae: Sigmodontinae) constitute a single evolutionary unit?
ABSTRACT The nominal species Calomys tener (Winge, 1887) ranges broadly in open lands of the Caatinga, Cerrado, Pantanal and Mata Atlântica of Brazil, and was recently reported from the Pampas of southern Brazil, and in the Selva Paranaense of eastern Paraguay and northeastern Argentina. This rodent can be infected with the pathogenic Araraquara hantavirus
Zoologia (Curitiba). Publicado em: 06/06/2019
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11. Association between MBL2 haplotypes and dengue severity in children from Rio de Janeiro, Brazil
BACKGROUND Dengue is an arthropod-borne viral disease with a majority of asymptomatic individuals and clinical manifestations varying from mild fever to severe and potentially lethal forms. An increasing number of genetic studies have outlined the association between host genetic variations and dengue severity. Genes associated to viral recognition and ent
Mem. Inst. Oswaldo Cruz. Publicado em: 23/05/2019
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12. Polymorphisms in the IL17A gene are not involved in the development of preeclampsia in the Brazilian population
RESUMO Introdução: A pré-eclâmpsia (PE) é definida pelo desenvolvimento de hipertensão arterial associada à proteinúria após a semana de gestação em mulheres previamente normotensas. A interleucina 17A (IL17A) é um potente indutor de inflamação tecidual, e polimorfismos no gene IL17A podem modular a expressão gênica e afetar o funcionamento
J. Bras. Patol. Med. Lab.. Publicado em: 23/05/2019