Galectin 3
Mostrando 1-12 de 48 artigos, teses e dissertações.
-
1. Serum galectin-3 levels are decreased in schizophrenia
Objective: To determine whether changes in serum galectin-3 (gal-3) concentrations in schizophrenia patients have etiopathogenetic importance. Since very little research has assessed the connection between galectins and schizophrenia, we wanted to examine alterations in the inflammatory marker gal-3 in schizophrenia and investigate possible correlations bet
Braz. J. Psychiatry. Publicado em: 2020-08
-
2. Effect of Artemisia apiacea Hance on growth performance, cecal opportunistic bacteria, and microbicidal peptides in rabbits
ABSTRACT This study aimed to investigate the effect of Artemisia apiacea Hance supplementation on growth performance, cecal opportunistic bacteria, and antimicrobial defense using 120 rabbits. There were four experimental diets containing a control and A. apiacea Hance added at doses of 25, 50, and 75 g kg−1 of feed. The trial lasted for 70 days. The resul
R. Bras. Zootec.. Publicado em: 28/11/2019
-
3. Galectin 3: an extraordinary multifunctional protein in dermatology. Current knowledge and perspectives
Abstract: Galectin 3 is a unique ~31 kDa protein that recognizes the N-acetyl-lactosamine structure of several glycoconjugates. It mainly occurs in epithelial and myeloid cells, but is also found in a variety of human cell types. In view of the crucial role played by galectin 3 in the regulation of cellular processes of essential importance and in the pathog
An. Bras. Dermatol.. Publicado em: 29/07/2019
-
4. Evaluation of Galectin-3 and Myocardial Fibrosis in Patients with Hypertrophic Cardiomyopathy
Abstract Background: Galectin-3 is the designation given to the protein that binds to ß-galactosides, expressed by activated macrophages and described as a cardiac fibrosis mediator. In hypertrophic cardiomyopathy (HCM), myocardial fibrosis is an independent predictor of adverse outcome; however, the association between Galectin-3 and myocardial fibrosis
Int. J. Cardiovasc. Sci.. Publicado em: 18/02/2019
-
5. Overexpression of ezrin and galectin-3 as predictors of poor prognosis of cervical cancer
The aim of this study was to explore the correlation of ezrin and galectin-3 expressions with prognosis in cervical cancer. The immunohistochemical method was applied to detect ezrin and galectin-3 expressions in normal cervix tissues (n=30), cervicitis tissues (n=28), cervical intraepithelial neoplasia (CIN) tissues (classified as I-III, n=89), and cervical
Braz J Med Biol Res. Publicado em: 23/03/2017
-
6. Expression and possible functional role of galectin-3 in the / Expressão e possível papel funcional da galectina-3 no timo de camundongos diabéticos não-obesos (NOD)
Galectin-3 belongs to a family of endogenous lectins which bind to -galactosides presented on the cell surface and extracellular matrix glycoproteins. It is involved in multiple biological functions such as cell growth, adhesion, proliferation and apoptosis. Moreover, galectin-3 is found in several tissues and organs, being highly conserved among animal spec
Publicado em: 2010
-
7. Immunolocalization of galectin-3 in mouse public symphysis during pregnancy and post-partum / Imunolocalização de galectina-3 na sinfise pubica de camundongos durante a prenhez e pos-parto
It is recognized that the pubic symphysis of some mammal species, including mice, undergoes structural transformations during pregnancy and post-partum. These transformations include the emerging of an interpubic ligament and softening of this tissue in the two last days of pregnancy. This ligament allows the pelvic bones separation, warranting fetus self pa
Publicado em: 2009
-
8. Analise de possiveis mecanismos e consequencias funcionais da expressão de galectina-3 em celulas de glioma expostas a condições hipoxicas / Analysis of possible mechanisms and functional consequences of galectin-3 expression in glioma cells exposed to hypoxia
Gliomas are primary Central Nervous System tumors. Among them, glioblastomas are the most common clinical forms and have the worst prognosis. In an attempt to understand glioma biology, the NG97 cell line was established. This cell line presents glioblastoma s characteristics, showing nuclear atipia and high growth rate. Recently, it was discovered that this
Publicado em: 2009
-
9. Expressão de galectina-1 e -3 na leucemia mielóide crônica e sua contribuição para a progressão da doença. / Expression of galectin-1 and -3 in chronic myeloid leukemia and its contribution to disease progression.
A galectina-1 (LGALS1) participa em diferentes etapas da neoplasia, mas sua função na leucemia mielóide crônica (LMC) é desconhecida. Neste trabalho, a expressão etópica de BCR-ABL selvagem, mas não de BCR-ABL quinase deficiente, em linhagens celulares hematopoéticas, resultou em aumento de LGALS1. O efeito foi revertido com a inibição da tirosina
Publicado em: 2009
-
10. Avaliação da progressão tumoral do câncer de laringe associada à infecção pelo Papilomavírus Humano (HPV) / Evaluation of tumor progression in laryngeal carcinoma associated with human Papilomavirus (HPV) infection.
Para que ocorra a transição do epitélio normal de laringe para carcinoma escamoso é necessário um processo de múltiplas etapas tal como exposição prolongada ao fumo e álcool e uma possível associação à infecção pelo HPV. Vários tipos de marcadores moleculares vêm sendo estudados na carcinogênese da laringe, entre eles proteínas associadas
Publicado em: 2009
-
11. Avaliação do papel da galectina-3 sobre funções de neutrófilos durante a infecção por cepa virulenta RH de Toxoplasma gondii em camundongos C57BL/6
Galectins are beta-galactoside-binding animal lectins involved in several biological processes, and Gal-3 has been related to modulation of immune reactions and inflammatory responses. The present study aimed to evaluate the influence of Gal-3 in neutrophil viability, early apoptosis and cell death in parallel with its biological functions after in vivo and
Publicado em: 2009
-
12. Avaliação do papel diagnóstico e prognóstico da expressão imunoistoquímica de NDRG1, osteonectina, VEGF-A, VEGF-C, Flk-1/KDR, HIF-1 e galectina-3 em espécimes tireoideanos por tissue microarrays / Study of the diagnostic and prognostic role of immunohistochemical expression of NDRG1, osteonectin, VEGF-A, VEGF-C, Flk-1/KDR, HIF-1 and galectin-3 in thyroid specimens by tissue microarray
INTRODUÇÃO: O crescimento e a progressão de diversos tipos de tumores dependem da angiogênese, isto é, a formação de novos vasos sanguíneos. Fatores da família do VEGF (VEGF-A, VEGF-C, Flk-1/KDR) são potentes mediadores da angiogênese e níveis elevados destes fatores podem ser detectados em vários tumores humanos. Outras proteínas como NDRG1, o
Publicado em: 2009