Excreted Secreted Antigens
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. Leishmaniose visceral canina e doença de Chagas em cães de Araguaína, Tocantins
Neste estudo foram analisadas amostras de soros de 111 cães machos e fêmeas, de idades variadas, provenientes do município de Araguaína, estado do Tocantins, Brasil. O diagnóstico sorológico para leishmaniose visceral canina foi realizado, inicialmente, no Laboratório Central (LACEN) de Araguaína, resultando em 61 amostras positivas na Reação de Im
Rev. Bras. Parasitol. Vet.. Publicado em: 25/06/2013
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2. Evaluation of excreted-secreted antigens of L. (L.) amazonensis, L. (V.) braziliensis and L. (L.) chagasi in immunodiagnosis of human and dog Visceral leishmaniasis. / Avaliação imunodiagnóstica de antígenos excretados-secretados de L. (L.) amazonensis, L. (V.) braziliensis e L.(L.) chagasi na Leishmaniose visceral humana e canina.
A Leishmaniose visceral é um problema que cresce no Estado de São Paulo afetando o homem e o cão. Os exoantígenos da membrana das leishmanias são liberados no meio de cultura. Os exoantígenos são importantes na indução da imunidade mediada pelas células T e B estimulando a produção elevada de anticorpos. Realizamos uma avaliação comparativa por
Publicado em: 2009
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3. Lagochilascaríase Experimental em Camundongos A/J e B10.A
Lagochilascariasis is an infection caused by a parasite from the genus Lagochilascaris and the species is Lagochilascaris minor Leiper 1909 Campos et al (1992) described its experimental evolutive cycle using a model constituted by mice as intermediate hosts and by domestic cats as definitive hosts The availability of murine strains with different genetic ch
Publicado em: 2006
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4. Lagochilascaríase Experimental em Camundongos A/J e B10.A
Lagochilascariasis is an infection caused by a parasite from the genus Lagochilascaris and the species is Lagochilascaris minor Leiper 1909 Campos et al (1992) described its experimental evolutive cycle using a model constituted by mice as intermediate hosts and by domestic cats as definitive hosts The availability of murine strains with different genetic ch
Publicado em: 2006
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5. Proteção imunológica contra a formação de cistos cerebrais em camundongos vacinados pela via nasal com proteínas recombinates de Toxoplasma gondii
Toxoplasma gondii is a protozoan parasite which can invade and reside in a wide range of host cells. It can infect all warm-blooded animals, including human being. Parasite invasion is associated with protein secretion from three organelles: micronemes, rhoptries and dense granules. These excreted/secreted antigens were highly immunogenic in humans and roden
Publicado em: 2006
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6. Análise de antígenos excretados-secretados de Trypanosoma cruzi por immunoblotting em gel bidimensional
Formas tripomastigotas de Trypanosoma cruzi excretam/secretam uma complexa mistura de moléculas antigênicas. Essa mistura é chamada trypomastigote excreted-secreted antigens e contém uma banda de massa molecular em torno de 150-160kDa que possui excelente performance para diagnóstico de doença de Chagas em immunoblotting. No presente estudo foi caracte
Revista da Sociedade Brasileira de Medicina Tropical. Publicado em: 2004-12
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7. Detection of antibodies to the 97 kDa component of Toxoplasma gondii in samples of human serum
This study was carried out to investigate the immune response against 97 kDa (p97) molecular marker of Toxoplasma gondii that has been characterized as a cytosolic protein and a component of the excreted-secreted antigens from this parasite. A total of 60 serum samples from patients were analyzed by enzime-linked immunosorbent assay and Western blot for toxo
Memórias do Instituto Oswaldo Cruz. Publicado em: 2002-10
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8. r-Sm14 - pRSETA efficacy in experimental animals
Previous studies carried out with Sm14 in experimental vaccination against Schistosoma mansoni or Fasciola hepatica infections were performed with recombinant Sm14 (rSm14) produced in Escherichia coli by the pGEMEX system (Promega). The rSm14 was expressed as a 40 kDa fusion protein with the major bacteriophage T7 capsid protein. Vaccination experiments with
Memórias do Instituto Oswaldo Cruz. Publicado em: 2001-09
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9. Protection of nude rats against Toxoplasma infection by excreted-secreted antigen-specific helper T cells.
In the present work we demonstrate the implication of excreted-secreted antigens in eliciting the protective cell-mediated immunity developed by rats toward Toxoplasma gondii. We first showed that 10(4) specific T cells from T. gondii-infected rats conferred to nude rats the ability to resist an infection by the highly virulent RH strain of T. gondii. In a s
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10. Isotypic profiles of antibody responses to Toxoplasma gondii infection in rats and mice: kinetic study and characterization of target antigens of immunoglobulin A antibodies.
The antibody responses to Toxoplasma gondii were investigated in rat and mouse experimental models. The immunoglobulin A (IgA) antibody response was of particular interest because acquisition of Toxoplasma gondii is usually by the oral route. The rat model was used because the natural resistance of rats to the parasite is similar to the natural resistance ex
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11. Shift of excretory-secretory immunogens of Trypanosoma cruzi during human Chagas' disease.
We studied secreted-excreted immunogens in human patients infected with Trypanosoma cruzi. A pair of 45- to 55-kDa antigens and a family of shed acute-phase antigens characterized the acute phase, while antibodies against a 160- to 170-kDa immunogen appeared at the chronic phase of the disease.
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12. Excretory-Secretory Antigens of Trypanosoma cruzi Are Potentially Useful for Serodiagnosis of Chronic Chagas' Disease
The reactivities of sera from chronic chagasic patients against the trypomastigote excreted-secreted antigens (TESA) of Trypanosoma cruzi strains with different biodemes were analyzed by TESA-blot and TESA–enzyme-linked immunosorbent assay (ELISA). Although both tests presented high sensitivity and specificity, TESA-ELISA is more appropriate for screening
American Society for Microbiology.