Dipyrone
Mostrando 1-12 de 64 artigos, teses e dissertações.
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1. Implantação de um protocolo de manejo de dor e redução do consumo de opioides na unidade de terapia intensiva: análise de série temporal interrompida
RESUMO Objetivo: Avaliar o impacto de um protocolo de manejo da dor e redução do consumo de opioides no consumo geral de opioides e nos desfechos clínicos. Métodos: Estudo em centro único, quasi-experimental, retrospectivo, de coortes antes e depois. Utilizamos uma série temporal interrompida para analisar as alterações no nível e na tendência de
Rev. bras. ter. intensiva. Publicado em: 20/01/2020
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2. Estudo da dor no período pós-operatório de cirurgia de catarata: utilização de dipirona no intraoperatório
Resumo Objetivos: Quantificar a dor dos pacientes submetidos a cirurgia de facoemulsificação sob anestesia tópica e anestesia tópica mais dipirona e avaliar se há correlação da dor com o tempo operatório, a graduação da catarta e a Energia Ultrassônica Dissipada Acumulada. Métodos: Cento e quatro olhos de 52 pacientes foram submetidos a cirurgi
Rev. bras.oftalmol.. Publicado em: 13/05/2019
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3. Pethidine in Low Doses versus Dipyrone for Pain Relief in Labor: A Randomized Controlled Trial
Resumo Objetivo Comparar doses baixas de petidina com dipirona na analgesia de parto. Métodos Em um estudo prospectivo randomizado realizado pela Universidade de Fortaleza, Ceará, Brasil, entre maio e dezembro de 2016, 200 parturientes a termo, com contrações uterinas muito dolorosas e apresentando dilatação do colo uterino ≥ 5 cm, foram selecion
Rev. Bras. Ginecol. Obstet.. Publicado em: 2019-02
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4. Effects of dipyrone on the digestive tract
Dipyrone (metamizole), acting through its main metabolites 4-methyl-amino-antipyrine and 4-amino-antipyrine, has established analgesic, antipyretic, and spasmolytic pharmacological effects, which are mediated by poorly known mechanisms. In rats, intravenously administered dipyrone delays gastric emptying (GE) of liquids with the participation of capsaicin-se
Braz J Med Biol Res. Publicado em: 10/01/2019
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5. The Antinociceptive Effect of the Leaves and Flowers Ethanolic Extracts of Tabebuia aurea (Silva Manso) Benth & Hook. F. ex S. Moore
ABSTRACT In view of the traditional use of Tabebuia aurea for treating pain and inflammation, the antinociceptive pharmacological potential of T. aurea ethanolic extracts (TAEE) was investigated through in vivo experimental models. First, the MTT assay was conducted to determine the potential cytotoxicity of the TAEEs. Afterwards, the acetic acid-induced wri
Braz. arch. biol. technol.. Publicado em: 29/11/2018
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6. Assessment of genetic integrity, splenic phagocytosis and cell death potential of (Z)-4-((1,5-dimethyl-3-oxo-2-phenyl-2,3dihydro-1H-pyrazol-4-yl) amino)-4-oxobut-2-enoic acid and its effect when combined with commercial chemotherapeutics
Abstract The increased incidence of cancer and its high treatment costs have encouraged the search for new compounds to be used in adjuvant therapies for this disease. This study discloses the synthesis of (Z)-4-((1,5-dimethyl-3-oxo-2-phenyl-2,3dihydro-1H-pyrazol-4-yl) amino)-4-oxobut-2-enoic acid (IR-01) and evaluates not only the action of this compound on
Genet. Mol. Biol.. Publicado em: 19/02/2018
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7. Synthesis, X-ray diffraction study and pharmacological evaluation of 3-amino-4-methylthiophene-2-acylcarbohydrazones
ABSTRACT N-acylhydrazone is an interesting privileged structure that has been used in the molecular design of a myriad of bioactive compounds. In order to identify new antinociceptive drug candidates, we described herein the design, synthesis, X-ray diffraction study and the pharmacological evaluation of a series of 3-amino-4-methylthiophene-2-acylcarbohydra
An. Acad. Bras. Ciênc.. Publicado em: 2018
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8. Dipyrone in association with atropine inhibits the effect on gastric emptying induced by hypoglycemia in rats
Atropine (AT) and dipyrone (Dp) induce a delay of gastric emptying (GE) of liquids in rats by inhibiting muscarinic receptors and activating β2-adrenergic receptors, respectively. The objective of the present study was to determine the effects of pretreatment with AT and Dp, given alone or in combination, on the effect of hypoglycemia in the liquid GE in ra
Braz J Med Biol Res. Publicado em: 31/08/2017
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9. Prevalence of potential drug-drug interactions in the intensive care unit of a Brazilian teaching hospital
Abstract Patients in intensive care unit are prescribed large numbers of drugs, highlighting the need to study potential Drug-Drug Interactions in this environment. The aim of this study was to delineate the prevalence and risk of potential drug-drug interactions between medications administered to patients in an ICU. This cross-sectional observational study
Braz. J. Pharm. Sci.. Publicado em: 20/04/2017
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10. Pharmacologic management of pain in patients with Chikungunya: a guideline
Abstract From the arrival of Chikungunya virus in the Americas in 2013 until March 2016, approximately two million cases of the disease have been reported. In Brazil, the virus was identified in 2014 and thousands of people have been affected. The disease has high attack rates, infecting 50% of a population within a few months. Approximately 50% of infected
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-12
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11. Effect of selective β-adrenoceptor blockade and surgical resection of the celiac-superior mesenteric ganglion complex on delayed liquid gastric emptying induced by dipyrone, 4-aminoantipyrine, and antipyrine in rats
There is evidence for participation of peripheral β-adrenoceptors in delayed liquid gastric emptying (GE) induced in rats by dipyrone (Dp), 4-aminoantipyrine (AA), and antipyrine (At). The present study aimed to determine whether β-adrenoceptors are involved in delayed GE induced by phenylpyrazole derivatives and the role of the prevertebral sympathetic ne
Braz J Med Biol Res. Publicado em: 02/02/2016
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12. Degradation of dipyrone by the electro-Fenton process in an electrochemical flow reactor with a modified gas diffusion electrode
A crescente ocorrência de antibióticos e seus metabólitos estão cada vez maiores em águas superficiais e subterrâneas, causando impactos significativos no meio ambiente e necessitando de desenvolvimento de novos tratamentos para a remoção completa de tais contaminantes. Este trabalho apresenta o estudo da eletrogeração de peróxido de hidrogênio (
J. Braz. Chem. Soc.. Publicado em: 2014-09