Demyelination
Mostrando 13-24 de 327 artigos, teses e dissertações.
-
13. NEUROPATOLOGIA DA CINOMOSE CANINA / NEUROPATHOLOGY OF CANINE DISTEMPER
Canine distemper is one of the most prevalent viral diseases of dogs. Several cases are diagnosed in a daily basis in private practices and veterinary hospitals around the country. Most cases of neurological manifestation of canine distemper are fatal and the diagnosis confirmation by histopathology is often necessary. Canine distemper encephalitis is the ma
Publicado em: 2009
-
14. Avaliação da atividade de nucleotidases e parâmetros de estresse oxidativo em pacientes com esclerose múltipla e em modelo experimental de desmielinização em ratos
A esclerose múltipla (EM) é a principal doença desmielinizante do sistema nervoso central (SNC), sendo considerada a principal causa de incapacidade neurológica em adultos jovens. Além das alterações imunes, neurológicas e vasculares que são encontradas na EM, tem sido postulado que o estresse oxidativo pode estar envolvido na patogênese desta doen
Publicado em: 2009
-
15. Efeitos da musicoterapia na qualidade de vida visual de portadores de neurite óptica desmielinizante
Background: Optic neuritis is an acute inflammatory disease of the optic nerve. Demyelinating optic neuritis (DON) is considered an isolated clinical syndrome because it can occur in the absence of any demyelination of the central nervous system or in association with multiple sclerosis (ON-MS). Visual quality of life (VQL) refers to the subjective perceptio
Publicado em: 2009
-
16. Anatomia ultraestrutural do nervo frênico de ratos: alterações decorrentes do diabete experimental crônico.
Streptozotocin (STZ) induced diabetes is known to cause a reduction of both conduction velocity and axon caliber in rat nerves and also a decrease in muscle fiber size. In the present study we investigated the phrenic nerve neuropathy, due to experimental diabetes induced by STZ and the evolution of this neuropathy in diabetic rats treated with insulin. Prox
Publicado em: 2008
-
17. C3c intrathecal synthesis evaluation in patients with multiple sclerosis
INTRODUCTION: Multiple sclerosis (MS) is a chronic, inflammatory and progressive disease of the central nervous system in which local inflammatory injuries of the brain white matter appears, being the most outstanding feature the myeline loss (demyelination). OBJECTIVE: To determine if the complement system might be involved in the MS immunopathogeny favouri
Arquivos de Neuro-Psiquiatria. Publicado em: 2007-09
-
18. O MODELO DESMIELINIZANTE DO BROMETO DE ETÍDIO (BE): ESTUDOS MORFOLÓGICOS EM CAMUNDONGOS C57BL/6 NORMAIS E KNOCKOUT PARA CONEXINA 32 / ETHIDIUM BROMIDE (EB) DEMYELINATING MODEL: MORPHOLOGIC STUDIES IN C57BL/6 NORMAL AND CX 32 KNOCKOUT MICE
Light and ultraestructural changes of central and peripheral nervous system lesions in mice KO for connexin-32 and submitted to the ethidium bromide gliotoxic demyelinating model are described. Their KO condition was tested with PCR and a negative connexin-32 labelling was performed by immunofluorescence. The experimental animals were C57BL/6 normal mice and
Publicado em: 2007
-
19. Efeito do interferon beta, da ciclosporina A, do ebselen e da vitamina E no sistema colinérgico e purinérgico de ratos normais e submetidos à desmielinização pelo brometo de etídio
A esclerose múltipla é a principal doença desmielinizante do sistema nervoso central (SNC). É considerada a principal causa de incapacidade neurológica em adultos jovens. O comprometimento cognitivo é muito comum nessa doença, envolvendo o aprendizado, a memória e a organização cortical do movimento, funções vitais que são reguladas pelo sistema
Publicado em: 2007
-
20. Delayed Schwann cell and oligodendrocyte remyelination after ethidium bromide injection in the brainstem of Wistar rats submitted to streptozotocin diabetogenic treatment
Schwann cell disturbance followed by segmental demyelination in the peripheral nervous system occurs in diabetic patients. Since Schwann cell and oligodendrocyte remyelination in the central nervous system is a well-known event in the ethidium bromide (EB) demyelinating model, the aim of this investigation was to determine the behavior of both cell types aft
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-05
-
21. ENZIMAS QUE HIDROLISAM NUCLEOTÍDEOS DE ADENINA EM SINAPTOSSOMAS DE CÓRTEX CEREBRAL E PLAQUETAS DE RATOS DESMIELINIZADOS PELO BROMETO DE ETÍDIO E TRATADOS COM INTERFERON-β / ENZYMES THAT HYDROLYZE ADENINE NUCLEOTIDES IN SYNAPTOSOMES FROM THE CEREBRAL CORTEX AND PLATELETS OF THE RATS DEMYELINATED BY ETHIDIUM BROMIDE AND TREATED WITH INTERFERON - β.
The activities of the enzymes NTPDase (E.C. 3.6.1.5, apyrase, CD39) and 5-nucleotidase (E.C. 3.1.3.5, CD73) were analyzed in synaptosomes from the cerebral cortex and platelets of rats submitted to demyelination by ethidium bromide (EB) associated with interferon-β (IFN-β) treatment. The following groups were studied: I - control (saline), II - (sa
Publicado em: 2006
-
22. Hepatitis C virus infection, cryoglobulinemia, and peripheral neuropathy: a case report
Hepatitis C virus (HCV) is essentially hepatotropic but its manifestations can extend beyond the liver. It can be associated with autoimmune diseases, such as mixed cryoglobulinemia, membranoproliferative glomerulonephritis, autoimmune thyroiditis, and lymphoproliferative disorders. The mechanisms that trigger these manifestations are not completely understo
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-12
-
23. ASTROCYTIC AND OLIGODENDROGLIAL RESPONSE OF THE BRAIN STEM OF IMMUNOSUPPRESSED WISTAR RATS SUBMITTED TO THE ETHIDIUM BROMIDE DEMYELINATING MODEL / RESPOSTA ASTROCITÁRIA E OLIGODENDROGLIAL NO TRONCO ENCEFÁLICO DE RATOS WISTAR IMUNOSSUPRIMIDOS E SUBMETIDOS AO MODELO DESMIELINIZANTE DO BROMETO DE ETÍDIO
Remielinização após desmielinização com brometo de etídio (BE) no tronco encefálico de ratos é realizada por oligodendrócitos e células de Schwann que invadem o tecido após a morte dos astrócitos. Embora a remielinização por oligodendrócitos seja detectada a partir dos 13 dias pós-intoxicação, a origem das células remielinizantes não é c
Publicado em: 2005
-
24. Evolução clinica da encefalomielite experimental auto-imune em camundongos geneticamente modificados (knockout) para a oxido nitrico sintase induzida
Multiple sclerosis (MS) is the most common human demyelinating disease of the central nervous system (CNS). Based on the fact that it shares similarities in relation to course of the disease and histology, Experimental auto-immune encephalomyelitis (EAE) has been used extensively as an animal model for MS. EAE is a Thl cell-mediated autoimmune disease induce
Publicado em: 2004