Dehydroepiandrosterone
Mostrando 1-12 de 100 artigos, teses e dissertações.
-
1. Total cholesterol/high-density lipoprotein and inflammatory parameters in patients with polycystic ovary syndrome
SUMMARY OBJECTIVE: In this study, the hormone profile, lipid profile, and inflammatory parameters of patients with polycystic ovary syndrome were compared with those of non-polycystic ovary syndrome patients to determine predictive markers in young polycystic ovary syndrome patients who have not yet had children. METHODS: Patients’ age, height, weight, b
Revista da Associação Médica Brasileira. Publicado em: 2022
-
2. Metabolic and hormonal assessment of adolescent and young adult women with prior premature adrenarche
OBJECTIVE: Follow-up studies of girls with premature adrenarche have reported the development of polycystic ovary syndrome, insulin resistance, and dyslipidemia and a propensity to cardiovascular disease. The aim of this study was to analyze the presence of these conditions in patients previously treated at the Universidade Federal do Triângulo Mineiro. M
Clinics. Publicado em: 19/06/2019
-
3. Relationship between sexual hormones, quality of life and postmenopausal sexual function
Resumo Objetivo Avaliar a relação entre hormônios sexuais, função sexual e qualidade de vida em mulheres na pós-menopausa. Métodos Estudo transversal com amostra de conveniência de 36 mulheres na pós-menopausa, com idades entre 45 e 65 anos, em seguimento ambulatorial de climatério. Humor, qualidade de vida, função sexual e perfil hormonal fo
Trends Psychiatry Psychother.. Publicado em: 30/05/2019
-
4. Low levels of dehydroepiandrosterone sulfate are associated with the risk of developing cardiac autonomic dysfunction in elderly subjects
ABSTRACT Objective: To assess the relationships between serum dehydroepiandrosterone sulfate (DHEA-S) levels and heart rate variability (HRV) among different age groups. Subjects and methods: Forty-five healthy men were divided into 3 groups: young age (YA; 20-39 yrs; n = 15), middle age (MA; 40-59 yrs; n = 15) and old age (OA; ≥ 60 yrs; n = 15). Hemodyn
Arch. Endocrinol. Metab.. Publicado em: 2019-01
-
5. Assessing endocrine and immune parameters in human immunodeficiency virus-infected patients before and after the immune reconstitution inflammatory syndrome
ABSTRACT Objective The present study compares immune and endocrine parameters between HIV-infected patients who underwent the Immune Reconstitution Inflammatory Syndrome (IRIS-P) during antiretroviral therapy (ART) and HIV-patients who did not undergo the syndrome (non-IRIS-P). Materials and methods Blood samples were obtained from 31 HIV-infected patients
Arch. Endocrinol. Metab.. Publicado em: 2018-02
-
6. DHEA and frontal fibrosing alopecia: molecular and physiopathological mechanisms
Abstract The transforming growth factor-beta 1 (TGFβ1) promotes fibrosis, differentiating epithelial cells and quiescent fibroblasts into myofibroblasts and increasing expression of extracellular matrix. Recent investigations have shown that PPAR (peroxisome proliferator-activated receptor*) is a negative regulator of fibrotic events induced by TGFβ1. Dehy
An. Bras. Dermatol.. Publicado em: 2016-12
-
7. A high corticosterone/DHEA-s ratio in young rats infected with Trypanosoma cruzi is associated with increased susceptibility
We have previously established that young male rats are more susceptible to the effects of Trypanosoma cruzi infection than adult rats. To explore underlying age-associated differences in disease outcome, we simultaneously assessed hormone levels and cytokine release throughout the acute infection period in young and adult rats infected with T. cruzi. Young
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-06
-
8. Evaluation in vitro and in vivo of the combined action of the hormones Dehydroepiandrosterone (DHEA) and Melatonin (MEL) against Trypanosoma cruzi. / Análise in vitro e in vivo da ação conjunta dos hormônios Dehidroepiandrosterona (DHEA) e Melatonina (MEL) contra Trypanosoma cruzi
Estudos prévios mostram que tanto a melatonina (MEL) como a Dehidroepiandrosterona (DHEA) aumentaram a resposta imune contra distintos parasitas. O presente estudo investigou a atividade in vitro da MEL e DHEA associados em um período de 24 horas e in vivo durante o curso da infecção por T. cruzi. A atividade in vitro da MEL e DHEA sozinhos, bem como jun
Publicado em: 2009
-
9. Administration of zinc and dehydroepiandrosterone (DHEA): would they exert a synergic role in the immune response of aged Wistar rats infected with Trypanosoma cruzi? / Administração de zinco de dehidroepiandrosterona (DHEA): exerceriam eles um papel sinérgico na resposta imune de ratos senis infectados com Trypanosoma cruzi?
A modulação das respostas imunológicas frente à administração de substâncias farmacologicamente ativas em modelos experimentais infectados por Trypanossoma cruzi tem contribuído de maneira importante nas investigações de novas terapias para a doença de Chagas. O presente estudo teve como objetivo avaliar um possível efeito sinérgico imunoestimul
Publicado em: 2008
-
10. Músculo esquelético e envelhecimento: vias de sinalização da insulina e IGF 1 nos diferentes tipos de fibras musculares, perfil morfológico e efeito do DHEA em ratos apresentando sarcopenia. / Skeletal muscle and insulin action: intracellular pathway in type 1 and type 2 muscle fibers, morphological pattern, and effect of DHEA in sarcopenic rats.
Reductions in skeletal muscle mass, increased insulin resistance, and decrements in several hormones serum levels, including DHEA, are features observed in aging. Twelve to fourteen months old rats present specific regulation in the insulin and the IGF-1 intracellular pathway in distinct skeletal muscle fiber composition and show reductions in size and propo
Publicado em: 2008
-
11. Efeito in vitro do deidroepiandrosterona (DHEA) sobre a via IRS/PI3-K/Akt e secreção de insulina em ilhotas pancreáticas de ratos. / Effect in vitro of dehydroepiandrosterone (DHEA) on IRS/PI3-K/Akt pathway and insulin secretion on rats pancreatic islets.
A administração de deidroepiandrosterona (DHEA) tem resultado em efeitos anti-diabetogênicos em animais de experimentação e no homem. Assim, o objetivo desse trabalho é avaliar o efeito do DHEA in vitro na expressão protéica do IR, do IRS-1, IRS-2, PI3-K, Akt, ERK-1/2; na expressão gênica do PDX-1, do PGC-1, da insulina, do GLUT-2 e da glicocinase;
Publicado em: 2008
-
12. Evaluation of the treatment with dehydroepiandrosterone in males and females Wistar rats during experimental Chagasdisease. / Avaliação do tratamento com dehidroepiandrosterona em ratos Wistarmachos e fêmeas durante a infecção chagásica experimental
Dehidroepiandrosterone (DHEA) has been considered for many researchers as the steroid of multiple functions. The immunologic stimulation triggered by DHEA has been demonstrated not only in animal models but also in humans. DHEA has been used as an alternative therapy to up-modulate immune response in host bearing viral, bacterial and parasitic infections. Th
Publicado em: 2007