Coumarin
Mostrando 1-12 de 178 artigos, teses e dissertações.
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1. Use of Paper Spray Mass Spectrometry for Determining the Chemical Profile of Green Cavendish Banana (Musa AAA) Peel and Pulp Flours and Evaluation of Its Functional Potential
Green Cavendish banana peel and pulp flours were obtained by three drying methods: oven dryer at 70 °C; air fryer at 180 °C and domestic oven at 180 °C, being the latter two new possibilities. Bioactive constituents using paper spray ionization mass spectrometry (PS-MS), phenolic identification and quantification by ultra-performance liquid chromatography
J. Braz. Chem. Soc.. Publicado em: 2021-05
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2. Inhibition of Acetylcholinesterase by Coumarin-Linked Amino Acids Synthetized via Triazole Associated with Molecule Partition Coefficient
A previous study for the identification of acetylcholinesterase (AChE) inhibitors demonstrated that the hybrid between tyrosol, the 1,2,3-triazole nucleus, and the coumarin group, namely 7-({1-[2-(4-hydroxyphenyl)ethyl]-1H-1,2,3-triazol-4-yl}methoxy)-4-methyl-2H-chromen-2-one (10), has a high enzyme inhibitory activity. Here, we synthesized analogues of 10 v
J. Braz. Chem. Soc.. Publicado em: 2021-03
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3. A IMPORTÂNCIA DAS CUMARINAS PARA A QUÍMICA MEDICINAL E O DESENVOLVIMENTO DE COMPOSTOS BIOATIVOS NOS ÚLTIMOS ANOS
Coumarins are natural products characterized as 2H-chromen-2-one, according to IUPAC nomenclature, largely distributed in plants, as well as, in species of fungi and bacteria. Nowadays, many synthetic procedures allow the discovery of coumarins with expanded chemical space. The ability to exert non-covalent interactions with many enzymes and receptors in liv
Quím. Nova. Publicado em: 2021-02
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4. KAURENOIC ACID DETERMINATION IN EXTRACT, TINCTURE AND SYRUP OF Mikania glomerata BY HPLC-QQQ-MS/MS
This work aims to develop a rapid and reliable method by HPLC-QqQ-MS/MS for identification and quantification of Kaurenoic acid (KA) in extract, tincture and syrup from Mikania glomerata. The developed method allows identifying and quantifying KA in complex samples obtained from extract marketed in pharmaceutical industry, a tincture prepared with the leaves
Quím. Nova. Publicado em: 2020-05
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5. Phytochemical management of root knot nematode (Meloidogyne incognita) kofoid and white chitwood by Artemisia spp. in tomato (Lycopersicon esculentum L.)
Resumo Experimentos in vitro e de triagem foram conduzidos para investigar a eficácia de treze constituintes fitoquímicos de Artemisia elegantissimia e A. incisa no nematóide de galhas, Meloidogyne incognita em tomateiro (Lycopersicon esculentum L.) cv. Rio Grande. Um controle positivo (carbofuran) e controle negativo (H2O) também foram utilizados para c
Braz. J. Biol.. Publicado em: 02/12/2019
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6. PHASE BEHAVIOR DATA AND THERMODYNAMIC MODELING OF THE BINARY SYSTEM {CO2 + COUMARIN} AT HIGH PRESSURES
Abstract In this work, vapor - liquid (VLE) equilibrium for the binary system carbon dioxide (1) + coumarin (2) at high pressures was measured by a static synthetic method using a variable-volume view cell. Experimental data were obtained in the temperature range of 318 - 338 K and pressures up to 20 MPa. Coumarin molar fraction ranged from 3.0x10-3 to 6.0x1
Braz. J. Chem. Eng.. Publicado em: 30/09/2019
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7. Radiation levels of UV-A and UV-B on growth parameters and coumarin content in guaco
RESUMO: Guaco é uma espécie medicinal que apresenta em sua composição a cumarina, um metabólito secundário cuja concentração no vegetal é influenciada por fatores como os níveis de radiação UV-A (315-400 nm) e UV-B (280-315 nm) incidentes, bem como pela idade e posição do órgão de armazenamento na planta. O objetivo deste estudo foi o de aval
Cienc. Rural. Publicado em: 13/06/2019
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8. Synthesis of some novel pyrimidine, thiophene, coumarin, pyridine and pyrrole derivatives and their biological evaluation as analgesic, antipyretic and anti-inflammatory agents
Pyrimidine derivative 3 was afforded through the reaction of compound (1) with 5-ureidohydantion (2). Product 3 underwent a cyclization to produce fused pyrimidine derivative 7, although the latter product 7 was synthesized through one step via the reaction of compound (1) with 5-ureidohydantion (2) using another catalyst. Compound 3 was oriented to react wi
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
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9. Protección antiincrustante de estructuras sumergidas mediante recubrimientos formulados con 7-hidroxi-4-metilcumarina
ABSTRACT Biofouling settlement on submerged structures such as ships, buoys, farms, off-shore platforms and meteorological stations induces economic losses as a consequence of material deterioration and withdraw from service. Environmental regulations focus on the use of environmental friendly products to replace metallic biocides included in antifouling pai
Matéria (Rio J.). Publicado em: 19/07/2018
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10. A new coumarin derivative, 4-acetatecoumarin, with antifungal activity and association study against Aspergillus spp.
Abstract Fungal infections have become a concern for health professionals, and the emergence of resistant strains has been reported for all known classes of antifungal drugs. Among the fungi causing disease, we highlight those that belong to the genus Aspergillus. For these reasons, the search for new antifungals is important. This study examines the effects
Braz. J. Microbiol.. Publicado em: 2018-06
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11. Total Synthesis of Altissimacoumarin D, a Small Molecule Sirtuin1 Activator
The total synthesis of the plant natural product altissimacoumarin D was achieved by the Mitsunobu alkylation of isofraxidin by geraniol. Isofraxidin was prepared from 2,4-dihydroxybenzaldehyde in five steps. The key reaction was the Knoevenagel condensation of an ortho-hydroxybenzaldehyde with Meldrum's acid under neutral conditions in water and one-pot aci
J. Braz. Chem. Soc.. Publicado em: 2018-05
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12. Nitric oxide inhibitory and anti-Bacillus activity of phenolic compounds and plant extracts from Mesua species
ABSTRACT Species from the genus Mesua, Calophyllaceae, are rich source for phenolic compounds such as coumarin xanthone, and benzophenone derivatives. An investigation on the potential biologically active phenolic compounds 1–5 and crude extracts from the stem bark of Mesua hexapetala (Hook. f.) P.S. Ashton and Mesua beccariana (Baill.) Kosterm. for nitric
Rev. bras. farmacogn.. Publicado em: 2018-04