Complement Pathway Mannosebinding Lectin
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Avaliação do sistema complemento e produção de anticorpos de pacientes HIV negativos com neurocriptococose / Antibody response to Cryptococcus sp and complement system activation in HIV negative patients with neurocryptococcosis
Cryptococcus sp é um fungo saprófita, cosmopolita, que causa micose sistêmica, geralmente, subaguda ou crônica, conhecida, sobretudo, por sua localização meníngea, após aquisição da infecção por via respiratória Embora seja ubíquo, a criptococose ocorre predominantemente em indivíduos imunodeficientes e podendo ocorrer, também, em indivíduos
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/10/2011
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2. Níveis séricos e polimorfismos gênicos da Lectina Ligadora de Manose (MBL) e da Serino Protease Associada à MBP (MASP)-2 em uma amostra da população brasileira / Mannose-binding lectin (MBL) and MBL Associated Serine Protease (MASP)-2 serum levels and genetic polymorphisms in a Brazilian population sample
A Lectina Ligadora de Manose (MBL) é uma proteína que reconhece carboidratos na superfície microbiana levando à ativação do sistema complemento. Este processo é mediado por Serino Proteases tal como a MASP-2. O complexo MBL/MASP-2 é responsável pela formação da C3 convertase C4bC2b. Os níveis séricos de MBL e a MASP-2 (genes MBL2 e MASP-2, respe
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/04/2011
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3. The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice
The complement system is an important component of the innate immune response to bacterial pathogens, including Streptococcus pneumoniae. The classical complement pathway is activated by antibody–antigen complexes on the bacterial surface and has been considered predominately to be an effector of the adaptive immune response, whereas the alternative and ma
National Academy of Sciences.
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4. Myocardial ischemia and reperfusion injury is dependent on both IgM and mannose-binding lectin
Complement activation has been shown to play an important role in the inflammation and tissue injury following myocardial ischemia and reperfusion (MI/R). Several recent studies from our laboratory demonstrated the importance of mannose-binding lectin (MBL) as the initiation pathway for complement activation and the resulting pathological effects following M
American Physiological Society.
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5. Origin of the classical complement pathway: Lamprey orthologue of mammalian C1q acts as a lectin
The lectin complement pathway in innate immunity is closely related to the classical complement pathway in adaptive immunity, with respect to the structures and functions of their components. Both pathways are initiated by complexes consisting of collagenous proteins and serine proteases of the mannose-binding lectin (MBL)-associated serine protease (MASP)/C
National Academy of Sciences.
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6. Deletion of wboA Enhances Activation of the Lectin Pathway of Complement in Brucella abortus and Brucella melitensis
Brucella spp. are gram-negative intracellular pathogens that survive and multiply within phagocytic cells of their hosts. Smooth organisms present O polysaccharides (OPS) on their surface. These OPS help the bacteria avoid the bactericidal action of serum. The wboA gene, coding for the enzyme glycosyltransferase, is essential for the synthesis of O chain in
American Society for Microbiology.
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7. H-ficolin serum concentration and susceptibility to fever and neutropenia in paediatric cancer patients
H-ficolin (Hakata antigen, ficolin-3) activates the lectin pathway of complement similar to mannose-binding lectin. However, its impact on susceptibility to infection is currently unknown. This study investigated whether the serum concentration of H-ficolin at diagnosis is associated with fever and neutropenia (FN) in paediatric cancer patients. H-ficolin wa
Blackwell Science Inc.