Clinically Isolated Syndrome
Mostrando 1-12 de 26 artigos, teses e dissertações.
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1. Prevalence and causes of congenital microcephaly in the absence of a Zika virus outbreak in southern Brazil
Resumo: Objetivo: Identificar as causas da microcefalia congênita no Rio Grande do Sul, Região Sul do Brasil, onde não foi detectado surto de ZIKV, de dezembro de 2015 a dezembro de 2016. Esse foi o período em que a infecção por ZIKV estava em seu auge no Nordeste do Brasil. Métodos: Este é um estudo transversal no qual todas as notificações de m
J. Pediatr. (Rio J.). Publicado em: 28/10/2019
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2. Type 2 leprosy reaction with Sweet's syndrome-like presentation
Abstract Leprosy is a chronic disease characterized by manifestations in the peripheral nerves and skin. The course of the disease may be interrupted by acute phenomena called reactions. This article reports a peculiar case of type 2 leprosy reaction with Sweet's syndrome-like features as the first clinical manifestation of leprosy, resulting in a delay in t
An. Bras. Dermatol.. Publicado em: 2016-06
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3. Novel mutations in the TBX5 gene in patients with Holt-Oram Syndrome
The Holt-Oram syndrome (HOS) is an autosomal dominant condition characterized by upper limb and cardiac malformations. Mutations in the TBX5 gene cause HOS and have also been associated with isolated heart and arm defects. Interactions between the TBX5, GATA4 and NKX2.5 proteins have been reported in humans. We screened the TBX5, GATA4, and NKX2.5 genes for
Genetics and Molecular Biology. Publicado em: 07/06/2010
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4. AvaliaÃÃo de pacientes com esclerose mÃltipla por meio de escalas de incapacidade
Patients with multiple sclerosis have varied degrees of disability depending on the damage to the neurological functions and their clinical consequences. However, the measurement of disability can vary according to the clinical scale being used, with prognostic and therapeutic consequences. In order to compare the assessment obtained by the main disability s
Publicado em: 2008
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5. Cytogenetics investigation on orofacial cleft individuals and screening of informative cases for further studies / Investigação citogenetica em individuos com fendas orofaciais e triagem dos casos informativos para estudos especificos
Cleft lip with or without cleft palate (CL/P) occurs in approximately 1/500 to 1/1000 newborns and cleft palate (CP), etiologically distinct, in approximately 0,4/1000 newborns. They have a complex etiology, and the great majority of clefts appear to be isolated anomalies, in which have been observed a very important genetic component. However, in a signific
Publicado em: 2007
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6. Avaliação polissonográfica e de função cardio-respiratória de adolescentes portadores de anemia falciforme clinicamente estáveis
Introduction: sickle cell anemia is the most prevalent hereditary disease in Brazil, occurring in 0,1 to 0,3% of the negro population. The occurrence of 1-3/1000 new annual cases in the country are also estimated, thus characterizing an important public health problem in our environment. Its also know that the prevalence of nocturnal desaturation of hemoglob
Publicado em: 2006
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7. Frequency of Werner helicase 1367 polymorphism and age-related morbidity in an elderly Brazilian population
Werner syndrome (WS) is a premature aging disease caused by a mutation in the WRN gene. The gene was identified in 1996 and its product acts as a DNA helicase and exonuclease. Some specific WRN polymorphic variants were associated with increased risk for cardiovascular diseases. The identification of genetic polymorphisms as risk factors for complex diseases
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-07
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8. Magnetic resonance imaging in clinically isolated lesions of the brain stem.
Twenty-seven patients with an isolated brain stem syndrome, thought to be due to demyelination, were examined by magnetic resonance imaging (MRI). A brain stem lesion was identified in 25, and clinically silent lesions outside the brain stem were demonstrated in 20. MRI was more sensitive than evoked potentials in detecting brain stem and other lesions. The
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9. Bacillus species pseudobacteremia traced to contaminated gloves used in collection of blood from patients with acquired immunodeficiency syndrome.
Ten nonpathogenic Bacillus isolates were obtained from blood cultures collected over a 2-year period. Eight of these isolates were from patient with acquired immunodeficiency syndrome, and seven were recovered from blood cultures obtained in outpatient clinics. Five cases occurred during a 5-month period. These five cases were clinically evaluated, and the B
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10. Experimental Campylobacter jejuni infection in the chicken: an animal model of axonal Guillain-Barré syndrome.
OBJECTIVE: To develop and characterise an animal model of paralytic neuropathy after Campylobacter jejuni infection. Campylobacter infection precedes development of many cases of Guillain-Barré syndrome and is particularly associated with cases having prominent axonal degeneration. Understanding the pathogenesis of Guillain-Barré syndrome after C jejuni in
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11. Isolated hemiataxia after supratentorial brain infarction.
Acute isolated hemiataxia is in most cases due to infratentorial (cerebellar) stroke. It has only twice been described in supratentorial stroke--namely, after thalamic infarction and a capsular haemorrhage. Three patients with isolated hemiataxia after a supratentorial brain infarct are described. These patients were seen in a period of five years during whi
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12. Molecular analysis of pyrogenic exotoxins from Streptococcus pyogenes isolates associated with toxic shock-like syndrome.
Toxic shock-like syndrome (TSLS) is characterized by hypotension or shock, fever, multiorgan system involvement, and a concurrent group A streptococcal infection. We analyzed 34 streptococcal strains isolated from patients with clinically well-documented TSLS for their pyrogenic toxin profiles and M-protein types. Although strains of nine different M types w