Chlorpheniramine
Mostrando 1-12 de 28 artigos, teses e dissertações.
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1. Efficacy of single dose antihistamine vs. single dose valerian-hops in subjective sleep measures among war refugees: a comparison trial
Abstract Background Many sedatives and anxiolytics are used in single dose or chronically to aid sleep. Clinically important sedatives include valerian-hops and antihistamines as they are used over the counter and are highly accessible and safe agents. Objectives To evaluate and compare a single dose of chlorpheniramine versus valerian-hops combination i
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2017-04
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2. Analysis of chlorpheniramine in human urine samples using dispersive liquid-liquid microextraction combined with high-performance liquid chromatography
Utilizou-se uma técnica de microextração simples e ambientalmente amigável para a determinação de clorfeniramina (CPM), anti-histamínico, em amostras de urina humana, utilizando a microextração dispersiva líquido-líquido (DLLME), seguida por cromatografia líquida de alta eficiência com detecção por arranjo de diodos (HPLC-DAD). Nesse método d
Braz. J. Pharm. Sci.. Publicado em: 2014-09
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3. Effect of histamine H1 and H2 receptor antagonists, microinjected into cerebellar vermis, on emotional memory consolidation in mice
This study investigated the effects of histamine H1 or H2 receptor antagonists on emotional memory consolidation in mice submitted to the elevated plus maze (EPM). The cerebellar vermis of male mice (Swiss albino) was implanted using a cannula guide. Three days after recovery, behavioral tests were performed in the EPM on 2 consecutive days (T1 and T2). Imme
Braz J Med Biol Res. Publicado em: 2014-02
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4. H1 but not H2 histamine antagonist receptors mediate anxiety-related behaviors and emotional memory deficit in mice subjected to elevated plus-maze testing
This study investigated the role of H1 and H2 receptors in anxiety and the retrieval of emotional memory using a Trial 1/Trial 2 (T1/T2) protocol in an elevated plus-maze (EPM). Tests were performed on 2 consecutive days, designated T1 and T2. Before T1, the mice received intraperitoneal injections of saline (SAL), 20 mg/kg zolantidine (ZOL, an H2receptor an
Braz J Med Biol Res. Publicado em: 19/04/2013
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5. O papel dos receptores histaminérgicos H1 da amídala na modulação da ansiedade e evocação da memória emocional em camundongos reexpostos ao labirinto em cruz elevado
O objetivo do presente estudo foi investigar o papel dos receptores histaminérgicos H1 sobre o déficit de evocação da memória emocional induzido pela Lhistidina. Para essa investigação, foi verificado o efeito da Clorfeniramina (CPA), antagonista H1, administrada na amídala, sobre a ansiedade e a evocação da memória emocional em camundongos submet
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/01/2012
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6. Clorfeniramina microinjetada no hipocampo dorsal reverte e efeito ansiolítico da L-histidina e prejudica a memória emocional de camundongos / Dorsal hippocampal microinjections of chlorpheniramine reverses anxiolitic-like effect of L-histidine and impairs mice emotional memory.
O nosso grupo tem investigado os efeitos da Clorfeniramina (CPA), antagonista H1, e da L-histidina (LH), uma droga precursora da síntese de histamina, sobre a ansiedade e a memória emocional. Diante disso, os objetivos desse estudo foram investigar os efeitos LH administrada i.p. e da CPA microinjetada no hipocampo dorsal sobre a ansiedade e a memória emo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/09/2011
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7. Chlorpheniramine impairs functional recovery in Carassius auratus after telencephalic ablation
We determined the effect of an H1 receptor antagonist on the functional recovery of Carassius auratus submitted to telencephalic ablation. Five days after surgery the fish underwent a spatial-choice learning paradigm test. The fish, weighing 6-12 g, were divided into four groups: telencephalic ablation (A) or sham lesion (S) and saline (SAL) or chlorpheniram
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-04
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8. Calibração multivariada de primeira e segunda ordem e figuras de merito na quantificação de enantiomeros por espectroscopia / First and second order multivariate calibration and figures of merit in the quantification of enantiomers by spectroscopy
First and second order multivariate calibration were developed for the quantification of enantiomers by spectroscopy and b-cyclodextrin guest-host complexes. In the first case, first order multivariate calibration was employed based on partial least square regression (PLS) for the quantification of the chlorpheniramine maleate enantiomers by ultraviolet (UV)
Publicado em: 2009
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9. Efeitos de antagonistas histaminérgicos H1 e H2 sobre a ansiedade e a memória emocional de camundongos
O objetivo do presente estudo foi avaliar o efeito da clorfeniramina e da zolantidina, antagonistas H1 e H2 respectivamente, sobre a ansiedade e a memória emocional de camundongos, por meio de dois experimentos. No primeiro experimento, utilizou-se três grupos de camundongos que foram determinados pelo tratamento farmacológico recebido por meio de injeç�
Publicado em: 2009
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10. Chlorpheniramine facilitates inhibitory avoidance in teleosts submitted to telencephalic ablation
The present study investigated the involvement of H(1) histaminegic receptor on the acquisition of inhibitory avoidance in Carassius auratus submitted to telencephalic ablation. The fish were submitted to telencephalic ablation 5 days before the experiment. The inhibitory avoidance procedure included 1 day for habituation, 3 days for training composed of 3 t
Brazilian Journal of Medical and Biological Research. Publicado em: 30/04/2008
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11. Chloroquine resistant Plasmodium falciparum malaria in Osogbo Nigeria: efficacy of amodiaquine + sulfadoxine-pyrimethamine and chloroquine + chlorpheniramine for treatment
Chloroquine (CQ) resistance in Plasmodium falciparum contributes to increasing malaria-attributable morbidity and mortality in Sub-Saharan Africa. Despite a change in drug policy, continued prescription of CQ did not abate. Therefore the therapeutic efficacy of CQ in uncomplicated falciparum malaria patients was assessed in a standard 28-day protocol in 116
Memórias do Instituto Oswaldo Cruz. Publicado em: 2008-02
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12. Enhancement of the antimalarial efficacy of amodiaquine by chlorpheniramine in vivo
Resistance in Plasmodium falciparum to amodiaquine (AQ) can be reversed in vitro with with antihistaminic and tricyclic antidepressant compounds, but its significance in vivo is unclear. The present report presents the enhancement of the antimalarial efficacy of AQ by chlorpheniramine, an H1 receptor antagonist that reverses chloroquine (CQ) resistance in vi
Memórias do Instituto Oswaldo Cruz. Publicado em: 10/05/2007