Cerebellum
Mostrando 13-24 de 797 artigos, teses e dissertações.
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13. Low-dose thioperamide injected into the cerebellar vermis of mice immediately after exposure to the elevated plus-maze impairs their avoidance behavior on re-exposure to the apparatus
The present study investigated the effect of thioperamide (THIO), an H3 histaminergic receptor antagonist, microinjected into the cerebellar vermis on emotional memory consolidation in male Swiss albino mice re-exposed to the elevated plus-maze (EPM). We implanted a guide cannula into the cerebellar vermis using stereotactic surgery. On the third day after s
Braz J Med Biol Res. Publicado em: 06/11/2013
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14. Rat vas deferens SERCA2 is modulated by Ca2+/calmodulin protein kinase II-mediated phosphorylation
Ca2+ pumps are important players in smooth muscle contraction. Nevertheless, little information is available about these pumps in the vas deferens. We have determined which subtype of sarco(endo)plasmic reticulum Ca2+-ATPase isoform (SERCA) is expressed in rat vas deferens (RVD) and its modulation by calmodulin (CaM)-dependent mechanisms. The thapsigargin-se
Braz J Med Biol Res. Publicado em: 19/03/2013
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15. Myosin Va is developmentally regulated and expressed in the human cerebellum from birth to old age
Myosin Va functions as a processive, actin-based motor molecule highly enriched in the nervous system, which transports and/or tethers organelles, vesicles, and mRNA and protein translation machinery. Mutation of myosin Va leads to Griscelli disease that is associated with severe neurological deficits and a short life span. Despite playing a critical role in
Braz J Med Biol Res. Publicado em: 2013-02
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16. Ontogênese de conexinas no cerebelo. / Ontogenesis of connexins in the cerebellum.
As junções comunicantes formadas por conexinas (Cx) ligam o citoplasma de células adjacentes e permitem a passagem de moléculas e íons entre elas. No sistema nervoso, esses canais constituem as sinapses elétricas e são fundamentais para a fisiologia glial. No desenvolvimento, as conexinas estão envolvidas nos processos de migração, proliferação e
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/07/2012
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17. Hippocampal-cerebellar involvement in enhancement of performance in word-based BRT with the presence of background noise: an initial fMRI study
Background noise may impose deleterious effects on cognitive processing. However, noise below the threshold level may increase the ability to detect stimuli via stochastic resonance mechanisms (SR). The present study investigates whether task performance is deteriorated or enhanced by 5-dB SNR and, if the task performance is enhanced, whether this facilitati
Psychol. Neurosci.. Publicado em: 2012-12
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18. Pediatric multiple sclerosis in Venezuela
OBJECTIVE: To describe the epidemiological and clinical characteristics of Venezuelan pediatric patients with multiple sclerosis (MS). METHODS: Database records from the National Program for MS were searched for patients with an established diagnosis of MS whose first symptoms appeared before age 18. RESULTS: The national database held records of 1.710 patie
Arquivos de Neuro-Psiquiatria. Publicado em: 2012-04
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19. Anticonvulsant activity of alcoholic root extract of Cardiospermum halicacabum
The aim of the present study was to evaluate the anticonvulsant effects of alcoholic root extract of Cardiospermum halicacabum L., Sapindaceae (ARECH), on the various murine models of epilepsy. The root extract of the plant was administered p.o. to male swiss albino mice at doses of 30, 100 and 300 mg/kg before evaluation. The brain monoamine levels were det
Revista Brasileira de Farmacognosia. Publicado em: 24/01/2012
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20. Spinocerebellar ataxias: genotype-phenotype correlations in 104 Brazilian families
OBJECTIVE: Spinocerebellar ataxias are neurodegenerative disorders involving the cerebellum and its connections. There are more than 30 distinct subtypes, 16 of which are associated with an identified gene. The aim of the current study was to evaluate a large group of patients from 104 Brazilian families with spinocerebellar ataxias. METHODS: We studied 150
Clinics. Publicado em: 2012
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21. Aspectos clínico-patológicos dos gangliogliomas da fossa posterior / Clinicopathological aspects of posterior fossa gangliogliomas
Gangliogliomas are rare central nervous system tumors, corresponding to 1,3% of all intracranial tumors. Usually they manifest clinically as epilepsy refractory to medical treatment. The most common location are the temporal lobes, followed by the frontal lobes. The infratentorial location is extremely rare with only 30 cases reported until 2007. Apparently
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/12/2011
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22. Correlação clínico-laboratorial e de imagem do lúpus eritematoso sistêmico e da esclerose múltipla no HC/FM/UFG em Goiânia/Goiás de 2009 a 2010: ênfase nas manifestações neurológicas / Correlation of clinical-laboratorial and image of lupus erythematosus and multiple sclerosis in HC/FM/UFG at Goiânia/Goiás, 2009 to 2010: emphasis on neurological manifestations
Systemic Lupus Erythematosus - LES is an autoimmune disease involving multiple systems. In the Central nervous system-SNC is one of his more severe manifestations. One of the frames of Lupus neuropsychiatric - LES-NP, is a Demyelinating Syndrome - SD. SD in rare cases, may be the first manifestation of LES, resembling multiple sclerosis - MS in their symptom
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/09/2011
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23. Deficiência de tiamina e isolamento social afetam aspectos do comportamento motor e níveis centrais de GABA e glutamato
The main phenomenon approached in this study is the motor behavior, evaluated after two different types of environmental stimuli, the consumption of diet deficient in B1 vitamin and/or social isolation. The B1 vitamin, thiamine, is an essential nutrient for the nervous tissue. In previous studies, our research group has shown that the maternal thiamine defic
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/07/2011
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24. Relação entre as alterações estruturais do cerebelo e os transtornos psiquiátricos / Relationship between structural cerebellar changes and psychiatric disorders
Classically it was attributed to the cerebellum only functions regarding the control of movements, posture and balance. However, several studies have shown that the cerebellum also participates in the control of cognition, emotional processing and behavior through direct and indirect pathways. New evidence suggests that the cerebellum has structural and func
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/06/2011