Biological Weapon
Mostrando 1-12 de 17 artigos, teses e dissertações.
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1. Humoral and cellular immune response of mice challenged with Yersinia pestis antigenic preparations
ABSTRACT Objectives: The plague, which is an infectious disease caused by Yersinia pestis, still threatens many populations in several countries. The worldwide increase in human plague cases and the potential use of the bacteria as a biological weapon reinforce the need to study the immunity that is induced by potential vaccine candidates. To determine the
Braz J Infect Dis. Publicado em: 2017-12
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2. Proposta de protocolos de segurança para a prevenção, a contenção e a neutralização de agente agressor bioativo em incidentes bioterroristas e estudo por docking molecular do fator letal do Bacillus anthracis (Antraz)
Há séculos agentes infecciosos são utilizados como armas em conflitos bélicos. Em 1972 a Convenção sobre Armas Biológicas proibiu a criação e armazenamento de armas biológicas. No entanto alguns países continuaram a pesquisa e o desenvolvimento dessas armas. Prova desse fato foi o acidente em 1979 em uma fábrica militar na URSS, onde foram disper
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/10/2010
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3. Mapeamento molecular criminal de crimes sexuais em série no Distrito Federal entre os anos de 1999 e 2009
The sexual violence is a universal phenomenon that reaches women, men and children. It is difficult to measure the real incidence of these crimes since this statistical data are underrated of social, psychological and biological aspect related to this type of violence. In biogenetic examination of biological material link to sexual crimes in Distrito Federal
Publicado em: 2010
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4. The public health implications of melioidosis
Melioidosis, which is caused by the bacterium Burkholderia pseudomallei, is a potentially fatal tropical infection, little known outside its main endemic zone of Southeast Asia and northern Australia. Though it has received more attention in recent years on account of its claimed suitability as a biological weapon agent, the principal threat from melioidosis
Brazilian Journal of Infectious Diseases. Publicado em: 2009-02
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5. ANTICIPATED BIOLOGICAL AND ENVIRONMENTAL EFFECTS OF DETONATING A TWENTY-MEGATON WEAPON ON COLUMBUS CIRCLE IN NEW YORK CITY
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6. Novel Sample Preparation Method for Safe and Rapid Detection of Bacillus anthracis Spores in Environmental Powders and Nasal Swabs
Bacillus anthracis spores have been used as a biological weapon in the United States. We wanted to develop a safe, rapid method of sample preparation that provided safe DNA for the detection of spores in environmental and clinical specimens. Our method reproducibly detects B. anthracis in samples containing <10 spores.
American Society for Microbiology.
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7. Rabbit and Nonhuman Primate Models of Toxin-Targeting Human Anthrax Vaccines
The intentional use of Bacillus anthracis, the etiological agent of anthrax, as a bioterrorist weapon in late 2001 made our society acutely aware of the importance of developing, testing, and stockpiling adequate countermeasures against biological attacks. Biodefense vaccines are an important component of our arsenal to be used during a biological attack. Ho
American Society for Microbiology.
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8. Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis—One Species on the Basis of Genetic Evidence
Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis are members of the Bacillus cereus group of bacteria, demonstrating widely different phenotypes and pathological effects. B. anthracis causes the acute fatal disease anthrax and is a potential biological weapon due to its high toxicity. B. thuringiensis produces intracellular protein crystals to
American Society for Microbiology.
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9. A Complex Adenovirus-Vectored Vaccine against Rift Valley Fever Virus Protects Mice against Lethal Infection in the Presence of Preexisting Vector Immunity▿
Rift Valley fever virus (RVFV) has been cited as a potential biological-weapon threat due to the serious and fatal disease it causes in humans and animals and the fact that this mosquito-borne virus can be lethal in an aerosolized form. Current human and veterinary vaccines against RVFV, however, are outdated, inefficient, and unsafe. We have incorporated th
American Society for Microbiology (ASM).
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10. The Future of Smallpox Vaccination: is MVA the key?
Eradication of the smallpox virus through extensive global vaccination efforts has resulted in one of the most important breakthroughs in medical history, saving countless lives from the severe morbidity and mortality that is associated with this disease. Although smallpox is now extinct in nature, laboratory stocks of this virus still remain and the subject
BioMed Central.
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11. The 1.51-Å structure of the poxvirus L1 protein, a target of potent neutralizing antibodies
Although eradicated from nature more than two decades ago, the threat of smallpox has reemerged because of concerns over its use as a biological weapon. We present the structure of the poxvirus L1 protein, a molecule that is conserved throughout the poxvirus family and is nearly identical in vaccinia virus and in variola virus, which causes smallpox. L1 is a
National Academy of Sciences.
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12. Structural flexibility in the Burkholderia mallei genome
The complete genome sequence of Burkholderia mallei ATCC 23344 provides insight into this highly infectious bacterium's pathogenicity and evolutionary history. B. mallei, the etiologic agent of glanders, has come under renewed scientific investigation as a result of recent concerns about its past and potential future use as a biological weapon. Genome analys
National Academy of Sciences.