Beta Thalassemia
Mostrando 1-12 de 176 artigos, teses e dissertações.
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1. Assessment of serum endocan levels in patients with beta-thalassemia minor
SUMMARY OBJECTIVE: Beta-thalassemia minor is a blood disease caused by a hereditary decrease in beta-globin synthesis, frequently leading to hypochromic microcytic anemia. Formerly called endothelial cell-specific molecule 1, endocan is a proteoglycan released by vascular endothelial cells in many organs. Our aim was to investigate the relationship between
Revista da Associação Médica Brasileira. Publicado em: 2022
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2. Serum endocan levels in patients with beta-thalassemia minor may be affected by age and gender
Revista da Associação Médica Brasileira. Publicado em: 2022
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3. Association of FOXO3 polymorphism (rs3800231) and clinical subphenotypes of beta thalassemic individuals
Abstract Introduction Studies have shown that the loss of the FOXO3 transcriptional function is involved in the pathophysiology of some chronic erythroid disorders, including beta-thalassemia (β-thal). Therefore, the single nucleotide polymorphism (SNP) rs3800231 (35-2764A > G) could contribute to alterations in its transcriptional activity, acting as a mo
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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4. Hemoglobinopathy and pediatrics in the time of COVID-19
ABSTRACT Introduction: It is important to know if patients with hemoglobinopathy could be more susceptible to COVID-19. Objective: Analyze SARS-CoV-2 infection in pediatric patients with hemoglobinopathy. Methods: Using the online platforms LILACS, PUBMED and EMBASE, on 17- JUL-2020 a search was made for the terms COVID-19 and SARS-CoV-2 associated with "
Hematol., Transfus. Cell Ther.. Publicado em: 2021-03
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5. Erythema annulare centrifugum associated with chronic amitriptyline intake,
ABSTRACT Introduction: It is important to know if patients with hemoglobinopathy could be more susceptible to COVID-19. Objective: Analyze SARS-CoV-2 infection in pediatric patients with hemoglobinopathy. Methods: Using the online platforms LILACS, PUBMED and EMBASE, on 17- JUL-2020 a search was made for the terms COVID-19 and SARS-CoV-2 associated with "
An. Bras. Dermatol.. Publicado em: 2021-02
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6. Nature and severity of dental malocclusion in children suffering from transfusion-dependent (-thalassemia major
RESUMO Objetivo: Avaliar a prevalência e gravidade da má oclusão em crianças que sofrem de beta-talassemia e mensurar a necessidade de tratamento ortodôntico usando o Índice de Prioridade de Tratamento (IPT) de Grainger e o Índice de Necessidade de Tratamento Ortodôntico (Index of Orthodontic Treatment Need - IOTN) - Componente de Saúde Dental (Den
Dental Press J. Orthod.. Publicado em: 2020-12
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7. Coinheritance of beta-thalassemia minor and hereditary pyropoikilocytosis: case report
Abstract Background This study aimed to describe the incidence, microbiological profile, and risk factors associated with bacteremia in pediatric patients with hematopoietic stem cell transplantation (HSCT). Methods A retrospective cohort study was performed on patients under 18 years old who underwent HSCT due to any indication, between January 2012 and J
Hematol., Transfus. Cell Ther.. Publicado em: 2020-03
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8. Epidemiology and risk factors of transfusion transmitted infections in thalassemia major: a multicenter study in Pakistan
ABSTRACT Background: Blood transfusion-transmitted infections in individuals suffering from beta-thalassemia have been reported in Pakistan, but the information on their sociodemographic and clinical determinants is lacking. This study aims to describe the prevalence, as well as the factors, contributing in blood transfusion-transmitted infections. Method:
Hematol., Transfus. Cell Ther.. Publicado em: 25/11/2019
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9. Vascular endothelial growth factor and pulmonary hypertension in children with beta thalassemia major
Resumo: Objetivo: A finalidade deste estudo foi exemplificar a associação entre o nível de fator de crescimento endotelial vascular e a hipertensão arterial pulmonar em crianças com talassemia beta maior. Método: Este estudo caso-controle foi realizado em 116 crianças com talassemia beta maior; 58 das quais apresentaram hipertensão arterial pulmona
J. Pediatr. (Rio J.). Publicado em: 28/10/2019
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10. Intraocular pressure in subjects with beta-thalassemia minor
RESUMO Objetivo: Beta-talassemia menor é uma doença hereditária comum no sangue em países mediterrâneos como a Turquia e está associada à resistência à insulina. A resistência à insulina por sua vez, pode estar associada à pressão intraocular excessivamente alta e, portanto à cegueira induzida pela pressão intraocular. Este estudo teve como o
Arq. Bras. Oftalmol.. Publicado em: 25/02/2019
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11. Foxo3 gene expression and oxidative status in beta-thalassemia minor subjects
ABSTRACT Background: Oxidative stress may aggravate symptoms of hemolytic anemias such as beta-thalassemia. FoxO3 activation results in resistance to oxidative stress in fibroblasts and neuronal cell cultures. Objective: The purpose of this research was to study FoxO3 gene expression and oxidative status in beta-thalassemia minor individuals. Methods: Six
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-06
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12. Cholelithiasis and its complications in sickle cell disease in a university hospital
Abstract Introduction: The clinical manifestations of sickle cell disease are related to the polymerization of hemoglobin S. The chronic hemolysis caused by this condition often causes the formation of gallstones that can migrate and block the common bile duct leading to acute abdomen. Objective: This study aimed to evaluate the profile of patients with si
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-03