Axotomy
Mostrando 1-12 de 79 artigos, teses e dissertações.
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1. The influence of selected pathological states on the somatostatin-like immunoreactive (SOM-LI) endocrine cells in the mucosal layer of the porcine descending colon
This study reports on changes in the number of somatostatin-like immunoreactive (SOM-LI) endocrine cells in the porcine descending colon, caused by chemically driven inflammation, axotomy and proliferative enteropathy (PE). The distribution pattern of SOM-LI endocrine cells has been studied using the routine single-labelling immunofluorescence technique. Sem
Pesq. Vet. Bras.. Publicado em: 2012-12
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2. Impacto da ausência do interferon gama na plasticidade sináptica após lesão do nervo isquiático / Interferon of impact gamma in the of synaptic plasticity after sciatic nerve lesion
Na medula espinal, o estabelecimento das sinapses é, provavelmente, coordenado pelos próprios neurônios. Contudo, as células da glia circunjacentes e o microambiente formado entre neurônios/glia, desempenham papel importante na modulação da excitabilidade neural, influenciando na transmissão e plasticidade sináptica. Em situações de injúria ou in
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/01/2011
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3. Caspase dependence of the death of neonatal retinal ganglion cells induced by axon damage and induction of autophagy as a survival mechanism
We examined the degeneration of post-mitotic ganglion cells in ex-vivo neonatal retinal explants following axon damage. Ultrastructural features of both apoptosis and autophagy were detected. Degenerating cells reacted with antibodies specific for activated caspase-3 or -9, consistent with the presence of caspase activity. Furthermore, peptidic inhibitors of
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-10
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4. Axotomy increases NADPH-diaphorase activity in the dorsal root ganglia and lumbar spinal cord of the turtle Trachemys dorbigni
Seven days after transection of the sciatic nerve NADPH-diaphorase activity increased in the small and medium neurons of the dorsal root ganglia of the turtle. However, this increase was observed only in medium neurons for up to 90 days. At this time a bilateral increase of NADPH-diaphorase staining was observed in all areas and neuronal types of the dorsal
Publicado em: 2010
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5. Influencia do MHC classico (Ia) e não-classico (Ib) e da oxido nitrico sintase induzivel (iNOS) na reação glial e na plasticidade das sinapses apos axotomia periferica / Influence of a classical (Ia) and non-classical (Ib) MHC I and inducible nitric oxide synthase (iNOS) on glial reaction and synaptic plasticity after peripheral axotomy
Após uma lesão de um nervo periférico, astrócitos e microglia tornam-se reativos, desencadeando a chamada gliose reativa. Adicionalmente, uma porcentagem significativa dos botões sinápticos em íntima relação com os motoneurônios é eliminada, sendo este mecanismo associado à ação de fagocitose das células gliais. Recentemente, a expressão de M
Publicado em: 2009
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6. Substance P immunoreactivity in the lumbar spinal cord of the turtle Trachemys dorbigni following peripheral nerve injury
Immunoreactive substance P was investigated in turtle lumbar spinal cord after sciatic nerve transection. In control animals immunoreactive fibers were densest in synaptic field Ia, where the longest axons invaded synaptic field III. Positive neuronal bodies were identified in the lateral column of the dorsal horn and substance P immunoreactive varicosities
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-04
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7. Ionic and metabolic dependence of axotomy-induced somatic membrane changes in crayfish.
1. Axotomy induces a transient change in the soma membrane from non-spiking to spiking in many neurones of the crayfish abdominal C.N.S. The ionic and metabolic dependence of this phenomenon was investigated in one identified neurone. 2. The inward current of axotomy-induced soma spikes is carried primarily by Na ions. 3. Addition of 50 mM-tetraethylammonium
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8. Effects of central or peripheral axotomy on membrane properties of sensory neurones in the petrosal ganglion of the cat.
1. The properties of sensory neurones in the petrosal ganglion of the cat were examined in vitro with intracellular electrodes 8 days after section of the central (bulbar roots) or peripheral process. Two types of cells, both with conduction velocities faster than 2 m/s and with humps on the falling phases of their action potentials (H-neurones), were studie
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9. c-Jun mediates axotomy-induced dopamine neuron death in vivo
Expression of the transcription factor c-Jun is induced in neurons of the central nervous system (CNS) in response to injury. Mechanical transection of the nigrostriatal pathway at the medial forebrain bundle (MFB) results in the delayed retrograde degeneration of the dopamine neurons in the substantia nigra pars compacta (SNc) and induces protracted express
The National Academy of Sciences.
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10. Changes in sodium and calcium channel activity following axotomy of B-cells in bullfrog sympathetic ganglion.
1. Currents mediated by Ca2+ channels using Ba2+ as a charge carrier (IBa), Na+ currents (INa) and voltage- and Ca(2+)-dependent K+ currents (IC) were recorded from bullfrog paravertebral sympathetic ganglion B-cells using whole-cell patch-clamp recording techniques. Currents recorded from control cells were compared with those from axotomized cells 13-15 da
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11. The effects of axotomy on bullfrog sympathetic neurones.
1. The effects of axotomy on the electrical properties of B cells in paravertebral sympathetic ganglia were studied using standard intracellular recording techniques. The effects were apparent after 1 week and persisted throughout the 47 days of study. 2. Action potential duration (spike width) and amplitude (spike height) were significantly increased in axo
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12. Effects of axotomy on the distribution of passive electrical properties of cat motoneurones.
Previously obtained experimental results concerning the effect of axotomy on motoneurone passive electrical properties have been re-analysed. As shown earlier, axotomy causes an average increase of motoneurone input resistance, membrane time constant and after-hyperpolarization duration. The present analysis suggests that the increased input resistance is re