Autoimmunity
Mostrando 1-12 de 563 artigos, teses e dissertações.
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1. Autoimmunity overlaps primary biliary cirrhosis: a not straightforward diagnosis
Revista da Associação Médica Brasileira. Publicado em: 2022
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2. Update on the pathogenesis of vitiligo
Abstract Vitiligo is a complex disease whose pathogenesis results from the interaction of genetic components, metabolic factors linked to cellular oxidative stress, melanocyte adhesion to the epithelium, and immunity (innate and adaptive), which culminate in aggression against melanocytes. In vitiligo, melanocytes are more sensitive to oxidative damage, lead
Anais Brasileiros de Dermatologia. Publicado em: 2022
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3. Influence of Metabolic Syndrome on the Recovery from Idiopathic Sudden Sensorineural Hearing Loss
Abstract Introduction Idiopathic sudden sensorineural hearing loss (ISSHL) is a disabling otologic urgency whose ethiopathogenesis is still controversial. Only in recent years metabolic syndrome (MetS) has been implicated as a possible aggravating factor in the prognosis of recovery from ISSHL. Objective To assess whether the preexistence of MetS interfere
International Archives of Otorhinolaryngology. Publicado em: 2022
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4. Immunodeficiencies: non-infectious manifestations
Abstract Objectives: Classical immunodeficiencies are mainly characterized by infectious conditions. In recent years, manifestations related to allergy, inflammation, autoimmunity, lymphoproliferation, and malignancies related to this group of diseases have been described. The text intends to make an update on the non-infectious manifestations of the primar
J. Pediatr. (Rio J.). Publicado em: 2021-04
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5. The first series of cases of ketosis-prone type 2 diabetes (flatbush diabetes) in Brazilian adults
SUMMARY Ketosis-prone type 2 diabetes (KPD) is an emerging form of diabetes mellitus characterized by unprovoked ketoacidosis, absence of autoimmunity and beta-cell dysfunction. The KPD may improve after initial glycemic compensation and evolve to exogenous insulin independence, most cases were observed in populations with African or Hispanic backgrounds. We
Arch. Endocrinol. Metab.. Publicado em: 2021-04
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6. Inborn Errors of Immunity: how to diagnose them?
Abstract Objectives: Inborn Errors of Immunity are characterized by infectious conditions and manifestations of immune dysregulation. The diversity of clinical phenotypes can make it difficult to direct the laboratory investigation. This article aims to update the investigation of immunological competence in the context of primary defects of the immune syst
J. Pediatr. (Rio J.). Publicado em: 2021-04
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7. Human Inborn Errors of Immunity (HIEI): predominantly antibody deficiencies (PADs): if you suspect it, you can detect it
Abstract Objective: This minireview gathers the scientific foundations of the literature on genetic errors in the development of the humoral immune system to help pediatricians suspect these defects. Sources: A systemic search using the PubMed MEDLINE database was performed for all Predominantly Antibody Deficiencies (PADs) described in the 2020 IUIS Exper
J. Pediatr. (Rio J.). Publicado em: 2021-04
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8. Failure of immunological competence: when to suspect?
Abstract Objectives: To draw physicians' attention to the different warning signs of diseases of inborn errors of immunity. Data sources: A non-systematic review of the literature was carried out in the PubMed, LILACS, and SciELO databases, in addition to consultation of reference textbooks. Summary of the findings: It is known that the lack of immunologi
J. Pediatr. (Rio J.). Publicado em: 2021-04
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9. Combined immunodeficiencies
Abstract Objectives: Inborn Errors of Immunity (IEI), also known as primary immunodeficiencies, correspond to a heterogeneous group of congenital diseases that primarily affect immune response components. The main clinical manifestations comprise increased susceptibility to infections, autoimmunity, inflammation, allergies and malignancies. The aim of this
J. Pediatr. (Rio J.). Publicado em: 2021-04
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10. Thyroid dysfunctions and autoimmunity in breast cancer patients: a prospective case-control study
ABSTRACT Objective: The relationship of thyroid dysfunction and autoimmunity with breast cancer (BC) continues to be contentious. The primary aim of this study was to estimate the prevalence of thyroid dysfunctions and autoimmunity in BC patients, and the secondary aims were to investigate the relationship of thyroid dysfunction with the clinicopathological
Arch. Endocrinol. Metab.. Publicado em: 2020-12
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11. Evaluation of the structure, autoimmunity, and functions of the thyroid gland in familial Mediterranean fever patients
ABSTRACT Objective Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disorder that is frequently seen in the eastern Mediterranean region. The thyroid gland can be affected in FMF patients through autoimmunity or amyloidosis. Here, we aimed to evaluate the structure and functions of the thyroid gland in addition to possible auto
Arch. Endocrinol. Metab.. Publicado em: 2020-02
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12. Insufficient iodine intake in pregnant women in different regions of the world: a systematic review
ABSTRACT Objective Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disorder that is frequently seen in the eastern Mediterranean region. The thyroid gland can be affected in FMF patients through autoimmunity or amyloidosis. Here, we aimed to evaluate the structure and functions of the thyroid gland in addition to possible auto
Arch. Endocrinol. Metab.. Publicado em: 2020-02