Tendências da incidência e da mortalidade por câncer de cólon em residentes no município de São Paulo / Trends in colon cancer incidence and mortality among residents of São Paulo

AUTOR(ES)
DATA DE PUBLICAÇÃO

2009

RESUMO

Introduction Studies on colon cancer show that its incidence worldwide has been increasing in the last century. There is evidence suggesting that this can be partially related to the industrialisation and urbanisation which occurred in the period and life style changes. Morbi-mortality associated with colon cancer observed in industrialised countries is greater than in developing countries. Colon cancer incidence presents an increasing trend for both sexes, probably due to a wider access to available diagnostic methods, while mortality rates remain stable. Objective: To assess incidence and mortality trends in patients with colon cancer, registered in São Paulo Cancer Registry. Methods: Temporal trends between 1997 and 2005 for incidence and between 1980 and 2007 for mortality were assessed. Analyses were performed separately by sex and age group, and effects of age, period and cohort were estimated by using Poisson´s regression model. Results: For all age groups assessed, there was an increase in colon cancer incidence in the city of São Paulo. The increase in mortality rates was lower than the increase in incidence which seems to coincide with a cohort effect present during the period studied. Increases in both incidence and mortality rates, were more pronounced among men. The age-period model presented the best adjustment to incidence coefficients for both sexes and the complete age-periodcohort model showed the best adjustment to mortality coefficients for both sexes. No significant statistical interaction for sex and incidence coefficient or sex and mortality coefficient was found. Conclusion: Results found in the present study revealed an increase in incidence and mortality rates, for both sexes and all age groups. A stabilisation in birth cohorts of colon cancer for both sexes was observed, suggesting that life style changes may contribute to the reduction in colon cancer mortality, especially in younger cohorts.

ASSUNTO(S)

incidence mortalidade incidência mortality tendência câncer de cólon colon cancer trends

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